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Conference Paper: Intervertebral disc transplantation: A biological approach to motion preservation

TitleIntervertebral disc transplantation: A biological approach to motion preservation
Authors
KeywordsAllograft
Degeneration
Intervertebral disc
Motion preservation
Transplantation
Issue Date2008
PublisherSpringer. The Journal's web site is located at http://www.springer.com/medicine/orthopedics/journal/586
Citation
European Spine Journal, 2008, v. 17 SUPPL. 4, p. S504-S510 How to Cite?
AbstractIntervertebral disc transplantation was developed in a bipedal animal model through the stages of autograft, fresh allograft and fresh frozen allograft. Results showed that the allografts were able to survive through a deep freezing protocol and maintain cell viability after transplantation without significant immunoreaction. Although degeneration of the allograft appeared to be inevitable, it was able to maintain stability and mobility of the functional spinal unit. These findings were similarly reproduced in the human clinical trial with excellent mid-term clinical results at 5 years. The process of evolution and findings were summarized in this review. © 2008 Springer-Verlag.
Persistent Identifierhttp://hdl.handle.net/10722/59479
ISSN
2015 Impact Factor: 2.132
2015 SCImago Journal Rankings: 0.972
PubMed Central ID
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorLuk, KDKen_HK
dc.contributor.authorRuan, DKen_HK
dc.date.accessioned2010-05-31T03:51:02Z-
dc.date.available2010-05-31T03:51:02Z-
dc.date.issued2008en_HK
dc.identifier.citationEuropean Spine Journal, 2008, v. 17 SUPPL. 4, p. S504-S510en_HK
dc.identifier.issn0940-6719en_HK
dc.identifier.urihttp://hdl.handle.net/10722/59479-
dc.description.abstractIntervertebral disc transplantation was developed in a bipedal animal model through the stages of autograft, fresh allograft and fresh frozen allograft. Results showed that the allografts were able to survive through a deep freezing protocol and maintain cell viability after transplantation without significant immunoreaction. Although degeneration of the allograft appeared to be inevitable, it was able to maintain stability and mobility of the functional spinal unit. These findings were similarly reproduced in the human clinical trial with excellent mid-term clinical results at 5 years. The process of evolution and findings were summarized in this review. © 2008 Springer-Verlag.en_HK
dc.languageengen_HK
dc.publisherSpringer. The Journal's web site is located at http://www.springer.com/medicine/orthopedics/journal/586en_HK
dc.relation.ispartofEuropean Spine Journalen_HK
dc.rightsThe original publication is available at www.springerlink.com-
dc.subjectAllograften_HK
dc.subjectDegenerationen_HK
dc.subjectIntervertebral discen_HK
dc.subjectMotion preservationen_HK
dc.subjectTransplantationen_HK
dc.subject.meshAnimals-
dc.subject.meshCervical Vertebrae - pathology - radiography - surgery-
dc.subject.meshGraft Survival - physiology-
dc.subject.meshIntervertebral Disk - anatomy and histology - physiology - transplantation-
dc.subject.meshIntervertebral Disk Displacement - complications - physiopathology - surgery-
dc.titleIntervertebral disc transplantation: A biological approach to motion preservationen_HK
dc.typeConference_Paperen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0940-6719&volume=17&issue=SUPPL. 4&spage=S504&epage=S510&date=2008&atitle=Intervertebral+disc+transplantation:+A+biological+approach+to+motion+preservationen_HK
dc.identifier.emailLuk, KDK:hcm21000@hku.hken_HK
dc.identifier.authorityLuk, KDK=rp00333en_HK
dc.description.naturelink_to_OA_fulltext-
dc.identifier.doi10.1007/s00586-008-0748-0en_HK
dc.identifier.pmid19005699-
dc.identifier.pmcidPMC2587662-
dc.identifier.scopuseid_2-s2.0-57049143102en_HK
dc.identifier.hkuros166632en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-57049143102&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume17en_HK
dc.identifier.issueSUPPL. 4en_HK
dc.identifier.spageS504en_HK
dc.identifier.epageS510en_HK
dc.identifier.isiWOS:000261195800011-
dc.publisher.placeGermanyen_HK
dc.identifier.scopusauthoridLuk, KDK=7201921573en_HK
dc.identifier.scopusauthoridRuan, DK=7004456354en_HK

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