File Download
 
Links for fulltext
(May Require Subscription)
 
Supplementary

Article: Identification of novel porcine and bovine parvoviruses closely related to human parvovirus 4
  • Basic View
  • Metadata View
  • XML View
TitleIdentification of novel porcine and bovine parvoviruses closely related to human parvovirus 4
 
AuthorsLau, SKP2
Woo, PCY2
Tse, H2
Fu, CTY2
Au, WK7
Chen, XC8
Tsoi, HW2
Tsang, THF4
Chan, JSY2
Tsang, DNC5
Li, KSM2
Tse, CWS1
Ng, TK3
Tsang, OTY3
Zheng, BJ2
Tam, S6
Chan, KH2
Zhou, B8
Yuen, KY2
 
Issue Date2008
 
PublisherSociety for General Microbiology. The Journal's web site is located at http://vir.sgmjournals.org
 
CitationJournal Of General Virology, 2008, v. 89 n. 8, p. 1840-1848 [How to Cite?]
DOI: http://dx.doi.org/10.1099/vir.0.2008/000380-0
 
AbstractHuman parvovirus 4 (PARV4), a recently discovered parvovirus found exclusively in human plasma and liver tissue, was considered phylogenetically distinct from other parvoviruses. Here, we report the discovery of two novel parvoviruses closely related to PARV4, porcine hokovirus (PHoV) and bovine hokovirus (BHoV), from porcine and bovine samples in Hong Kong. Their nearly full-length sequences were also analysed. PARV4-like viruses were detected by PCR among 44.4% (148/333) of porcine samples (including lymph nodes, liver, serum, nasopharyngeal and faecal samples), 13% (4/32) of bovine spleen samples and 2% (7/362) of human serum samples that were sent for human immunodeficiency virus and hepatitis C virus antibody tests. Three distinct parvoviruses were identified, including two novel parvoviruses, PHoV and BHoV, from porcine and bovine samples and PARV4 from humans, respectively. Analysis of genome pequences from seven PHoV strains, from three BHoV strains and from one PARV4 strain showed that the two animal parvoviruses were most similar to PARV4 with 61.5-63% nt identities and, together with PARV4 (HHoV), formed a distinct cluster within the family Parvoviridae. The three parvoviruses also differed from other parvoviruses by their relatively large predicted VP1 protein and the presence of a small unique conserved putative protein. Based on these results, we propose a separate genus, Hokovirus, to describe these three parvoviruses. The co-detection of porcine reproductive and respiratory syndrome virus, the agent associated with the recent 'high fever' disease outbreaks in pigs in China, from our porcine samples warrants further investigation. © 2008 SGM.
 
ISSN0022-1317
2012 Impact Factor: 3.127
2012 SCImago Journal Rankings: 1.245
 
DOIhttp://dx.doi.org/10.1099/vir.0.2008/000380-0
 
ISI Accession Number IDWOS:000258301800006
 
ReferencesReferences in Scopus
 
DC FieldValue
dc.contributor.authorLau, SKP
 
dc.contributor.authorWoo, PCY
 
dc.contributor.authorTse, H
 
dc.contributor.authorFu, CTY
 
dc.contributor.authorAu, WK
 
dc.contributor.authorChen, XC
 
dc.contributor.authorTsoi, HW
 
dc.contributor.authorTsang, THF
 
dc.contributor.authorChan, JSY
 
dc.contributor.authorTsang, DNC
 
dc.contributor.authorLi, KSM
 
dc.contributor.authorTse, CWS
 
dc.contributor.authorNg, TK
 
dc.contributor.authorTsang, OTY
 
dc.contributor.authorZheng, BJ
 
dc.contributor.authorTam, S
 
dc.contributor.authorChan, KH
 
dc.contributor.authorZhou, B
 
dc.contributor.authorYuen, KY
 
dc.date.accessioned2010-05-31T03:48:57Z
 
dc.date.available2010-05-31T03:48:57Z
 
dc.date.issued2008
 
dc.description.abstractHuman parvovirus 4 (PARV4), a recently discovered parvovirus found exclusively in human plasma and liver tissue, was considered phylogenetically distinct from other parvoviruses. Here, we report the discovery of two novel parvoviruses closely related to PARV4, porcine hokovirus (PHoV) and bovine hokovirus (BHoV), from porcine and bovine samples in Hong Kong. Their nearly full-length sequences were also analysed. PARV4-like viruses were detected by PCR among 44.4% (148/333) of porcine samples (including lymph nodes, liver, serum, nasopharyngeal and faecal samples), 13% (4/32) of bovine spleen samples and 2% (7/362) of human serum samples that were sent for human immunodeficiency virus and hepatitis C virus antibody tests. Three distinct parvoviruses were identified, including two novel parvoviruses, PHoV and BHoV, from porcine and bovine samples and PARV4 from humans, respectively. Analysis of genome pequences from seven PHoV strains, from three BHoV strains and from one PARV4 strain showed that the two animal parvoviruses were most similar to PARV4 with 61.5-63% nt identities and, together with PARV4 (HHoV), formed a distinct cluster within the family Parvoviridae. The three parvoviruses also differed from other parvoviruses by their relatively large predicted VP1 protein and the presence of a small unique conserved putative protein. Based on these results, we propose a separate genus, Hokovirus, to describe these three parvoviruses. The co-detection of porcine reproductive and respiratory syndrome virus, the agent associated with the recent 'high fever' disease outbreaks in pigs in China, from our porcine samples warrants further investigation. © 2008 SGM.
 
dc.description.naturepublished_or_final_version
 
dc.identifier.citationJournal Of General Virology, 2008, v. 89 n. 8, p. 1840-1848 [How to Cite?]
DOI: http://dx.doi.org/10.1099/vir.0.2008/000380-0
 
dc.identifier.doihttp://dx.doi.org/10.1099/vir.0.2008/000380-0
 
dc.identifier.epage1848
 
dc.identifier.hkuros143386
 
dc.identifier.isiWOS:000258301800006
 
dc.identifier.issn0022-1317
2012 Impact Factor: 3.127
2012 SCImago Journal Rankings: 1.245
 
dc.identifier.issue8
 
dc.identifier.openurl
 
dc.identifier.pmid18632954
 
dc.identifier.scopuseid_2-s2.0-50549098375
 
dc.identifier.spage1840
 
dc.identifier.urihttp://hdl.handle.net/10722/59382
 
dc.identifier.volume89
 
dc.languageeng
 
dc.publisherSociety for General Microbiology. The Journal's web site is located at http://vir.sgmjournals.org
 
dc.publisher.placeUnited Kingdom
 
dc.relation.ispartofJournal of General Virology
 
dc.relation.referencesReferences in Scopus
 
dc.rightsJournal of General Virology. Copyright © Society for General Microbiology.
 
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License
 
dc.rightsThis is an author manuscript that has been accepted for publication in [Journal Title], copyright Society for General Microbiology, but has not been copy-edited, formatted or proofed. Cite this article as appearing in [Journal Title]. This version of the manuscript may not be duplicated or reproduced, other than for personal use or within the rule of 'Fair Use of Copyrighted Materials' (section 17, Title 17, US Code), without permission from the copyright owner, Society for General Microbiology. The Society for General Microbiology disclaims any responsibility or liability for errors or omissions in this version of the manuscript or in any version derived from it by any other parties. The final copy-edited, published article, which is the version of record, can be found at [Journal URL], and is freely available without a subscription.
 
dc.subject.meshBocavirus - classification - genetics - isolation and purification
 
dc.subject.meshCattle Diseases - virology
 
dc.subject.meshParvoviridae Infections - veterinary - virology
 
dc.subject.meshParvovirinae - classification - genetics - isolation and purification
 
dc.subject.meshParvovirus - classification - genetics - isolation and purification
 
dc.titleIdentification of novel porcine and bovine parvoviruses closely related to human parvovirus 4
 
dc.typeArticle
 
<?xml encoding="utf-8" version="1.0"?>
<item><contributor.author>Lau, SKP</contributor.author>
<contributor.author>Woo, PCY</contributor.author>
<contributor.author>Tse, H</contributor.author>
<contributor.author>Fu, CTY</contributor.author>
<contributor.author>Au, WK</contributor.author>
<contributor.author>Chen, XC</contributor.author>
<contributor.author>Tsoi, HW</contributor.author>
<contributor.author>Tsang, THF</contributor.author>
<contributor.author>Chan, JSY</contributor.author>
<contributor.author>Tsang, DNC</contributor.author>
<contributor.author>Li, KSM</contributor.author>
<contributor.author>Tse, CWS</contributor.author>
<contributor.author>Ng, TK</contributor.author>
<contributor.author>Tsang, OTY</contributor.author>
<contributor.author>Zheng, BJ</contributor.author>
<contributor.author>Tam, S</contributor.author>
<contributor.author>Chan, KH</contributor.author>
<contributor.author>Zhou, B</contributor.author>
<contributor.author>Yuen, KY</contributor.author>
<date.accessioned>2010-05-31T03:48:57Z</date.accessioned>
<date.available>2010-05-31T03:48:57Z</date.available>
<date.issued>2008</date.issued>
<identifier.citation>Journal Of General Virology, 2008, v. 89 n. 8, p. 1840-1848</identifier.citation>
<identifier.issn>0022-1317</identifier.issn>
<identifier.uri>http://hdl.handle.net/10722/59382</identifier.uri>
<description.abstract>Human parvovirus 4 (PARV4), a recently discovered parvovirus found exclusively in human plasma and liver tissue, was considered phylogenetically distinct from other parvoviruses. Here, we report the discovery of two novel parvoviruses closely related to PARV4, porcine hokovirus (PHoV) and bovine hokovirus (BHoV), from porcine and bovine samples in Hong Kong. Their nearly full-length sequences were also analysed. PARV4-like viruses were detected by PCR among 44.4% (148/333) of porcine samples (including lymph nodes, liver, serum, nasopharyngeal and faecal samples), 13% (4/32) of bovine spleen samples and 2% (7/362) of human serum samples that were sent for human immunodeficiency virus and hepatitis C virus antibody tests. Three distinct parvoviruses were identified, including two novel parvoviruses, PHoV and BHoV, from porcine and bovine samples and PARV4 from humans, respectively. Analysis of genome pequences from seven PHoV strains, from three BHoV strains and from one PARV4 strain showed that the two animal parvoviruses were most similar to PARV4 with 61.5-63% nt identities and, together with PARV4 (HHoV), formed a distinct cluster within the family Parvoviridae. The three parvoviruses also differed from other parvoviruses by their relatively large predicted VP1 protein and the presence of a small unique conserved putative protein. Based on these results, we propose a separate genus, Hokovirus, to describe these three parvoviruses. The co-detection of porcine reproductive and respiratory syndrome virus, the agent associated with the recent &apos;high fever&apos; disease outbreaks in pigs in China, from our porcine samples warrants further investigation. &#169; 2008 SGM.</description.abstract>
<language>eng</language>
<publisher>Society for General Microbiology. The Journal&apos;s web site is located at http://vir.sgmjournals.org</publisher>
<relation.ispartof>Journal of General Virology</relation.ispartof>
<rights>Journal of General Virology. Copyright &#169; Society for General Microbiology.</rights>
<rights>Creative Commons: Attribution 3.0 Hong Kong License</rights>
<rights>This is an author manuscript that has been accepted for publication in [Journal Title], copyright Society for General Microbiology, but has not been copy-edited, formatted or proofed. Cite this article as appearing in [Journal Title]. This version of the manuscript may not be duplicated or reproduced, other than for personal use or within the rule of &apos;Fair Use of Copyrighted Materials&apos; (section 17, Title 17, US Code), without permission from the copyright owner, Society for General Microbiology. The Society for General Microbiology disclaims any responsibility or liability for errors or omissions in this version of the manuscript or in any version derived from it by any other parties. The final copy-edited, published article, which is the version of record, can be found at [Journal URL], and is freely available without a subscription.</rights>
<subject.mesh>Bocavirus - classification - genetics - isolation and purification</subject.mesh>
<subject.mesh>Cattle Diseases - virology</subject.mesh>
<subject.mesh>Parvoviridae Infections - veterinary - virology</subject.mesh>
<subject.mesh>Parvovirinae - classification - genetics - isolation and purification</subject.mesh>
<subject.mesh>Parvovirus - classification - genetics - isolation and purification</subject.mesh>
<title>Identification of novel porcine and bovine parvoviruses closely related to human parvovirus 4</title>
<type>Article</type>
<identifier.openurl>http://library.hku.hk:4550/resserv?sid=HKU:IR&amp;issn=0022-1317&amp;volume=89&amp;issue=8&amp;spage=1840&amp;epage=1848&amp;date=2008&amp;atitle=Identification+of+novel+porcine+and+bovine+parvoviruses+closely+related+to+human+parvovirus+4</identifier.openurl>
<description.nature>published_or_final_version</description.nature>
<identifier.doi>10.1099/vir.0.2008/000380-0</identifier.doi>
<identifier.pmid>18632954</identifier.pmid>
<identifier.scopus>eid_2-s2.0-50549098375</identifier.scopus>
<identifier.hkuros>143386</identifier.hkuros>
<relation.references>http://www.scopus.com/mlt/select.url?eid=2-s2.0-50549098375&amp;selection=ref&amp;src=s&amp;origin=recordpage</relation.references>
<identifier.volume>89</identifier.volume>
<identifier.issue>8</identifier.issue>
<identifier.spage>1840</identifier.spage>
<identifier.epage>1848</identifier.epage>
<identifier.isi>WOS:000258301800006</identifier.isi>
<publisher.place>United Kingdom</publisher.place>
<bitstream.url>http://hub.hku.hk/bitstream/10722/59382/1/Content.pdf</bitstream.url>
</item>
Author Affiliations
  1. Kwong Wah Hospital
  2. The University of Hong Kong
  3. Princess Margaret Hospital Hong Kong
  4. Centre for Health Protection
  5. Queen Elizabeth Hospital Hong Kong
  6. Queen Mary Hospital Hong Kong
  7. Food and Environmental Hygiene Department
  8. Shenzhen East Lake Hospital