Article: Gastroesophageal reflux disease is associated with poor asthma control, quality of life, and psychological status in Chinese asthma patients

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TitleGastroesophageal reflux disease is associated with poor asthma control, quality of life, and psychological status in Chinese asthma patients
AuthorsCheung, TK
Lam, B
Lam, KF1
Ip, M
Ng, C
Kung, R
Wong, BCY1
Issue Date2009
PublisherAmerican College of Chest Physicians. The Journal's web site is located at http://www.chestjournal.org
CitationChest, 2009, v. 135 n. 5, p. 1181-1185 [How to Cite?]
DOI: http://dx.doi.org/10.1378/chest.08-1702
AbstractBackground: Both asthma and gastroesophageal reflux disease (GERD) are common, often coexist, and have significant impact on a patient's quality of life. Our aim was to determine the prevalence of GERD in asthmatic patients at a major hospital in Hong Kong, and to examine the impact of GERD and its association with asthma control. Methods: Patients with asthma who attended the respiratory clinic at Queen Mary Hospital, Hong Kong, were recruited. Demographic data were collected, and a validated Chinese GERD questionnaire was used. The Medical Outcomes Study 36-item short form (SF-36) was used to assess quality of life, and the Hospital Anxiety and Depression Scale (HADS) was used to assess psychological status. Asthma control was assessed by the asthma control test. Results: A total of 218 patients were recruited; 40.4% of asthmatic patients (88 patients) had GERD, as defined by the GERD questionnaire. Compared with those patients without GERD, those with GERD had significantly worse asthma control (p = 0.022), worse quality of life in all domains of the SF-36 (all p < 0.01), and more anxiety (6.82 vs 4.90, respectively; p < 0.001) and depression (6.09 vs 4.05, respectively; p < 0.001) as reflected by HADSs. Conclusions: A significant proportion of asthmatic patients in Hong Kong have GERD, and this is associated with poorer asthmatic control, quality of life, and psychological status. Copyright © 2009 American College of Chest Physicians.
ISSN0012-3692
2011 Impact Factor: 5.25
2011 SCImago Journal Rankings: 0.497
DOIhttp://dx.doi.org/10.1378/chest.08-1702
ISI Accession Number IDWOS:000265876100012
ReferencesReferences in Scopus
DC Field
Value
dc.contributor.authorCheung, TK
dc.contributor.authorLam, B
dc.contributor.authorLam, KF
dc.contributor.authorIp, M
dc.contributor.authorNg, C
dc.contributor.authorKung, R
dc.contributor.authorWong, BCY
dc.date.accessioned2010-05-31T03:47:57Z
dc.date.available2010-05-31T03:47:57Z
dc.date.issued2009
dc.description.abstractBackground: Both asthma and gastroesophageal reflux disease (GERD) are common, often coexist, and have significant impact on a patient's quality of life. Our aim was to determine the prevalence of GERD in asthmatic patients at a major hospital in Hong Kong, and to examine the impact of GERD and its association with asthma control. Methods: Patients with asthma who attended the respiratory clinic at Queen Mary Hospital, Hong Kong, were recruited. Demographic data were collected, and a validated Chinese GERD questionnaire was used. The Medical Outcomes Study 36-item short form (SF-36) was used to assess quality of life, and the Hospital Anxiety and Depression Scale (HADS) was used to assess psychological status. Asthma control was assessed by the asthma control test. Results: A total of 218 patients were recruited; 40.4% of asthmatic patients (88 patients) had GERD, as defined by the GERD questionnaire. Compared with those patients without GERD, those with GERD had significantly worse asthma control (p = 0.022), worse quality of life in all domains of the SF-36 (all p < 0.01), and more anxiety (6.82 vs 4.90, respectively; p < 0.001) and depression (6.09 vs 4.05, respectively; p < 0.001) as reflected by HADSs. Conclusions: A significant proportion of asthmatic patients in Hong Kong have GERD, and this is associated with poorer asthmatic control, quality of life, and psychological status. Copyright © 2009 American College of Chest Physicians.
dc.description.natureLink_to_subscribed_fulltext
dc.identifier.citationChest, 2009, v. 135 n. 5, p. 1181-1185 [How to Cite?]
DOI: http://dx.doi.org/10.1378/chest.08-1702
dc.identifier.doihttp://dx.doi.org/10.1378/chest.08-1702
dc.identifier.epage1185
dc.identifier.hkuros157341
dc.identifier.isiWOS:000265876100012
dc.identifier.issn0012-3692
2011 Impact Factor: 5.25
2011 SCImago Journal Rankings: 0.497
dc.identifier.issue5
dc.identifier.openurl
dc.identifier.pmid19118263
dc.identifier.scopuseid_2-s2.0-65949105259
dc.identifier.spage1181
dc.identifier.urihttp://hdl.handle.net/10722/59336
dc.identifier.volume135
dc.languageeng
dc.publisherAmerican College of Chest Physicians. The Journal's web site is located at http://www.chestjournal.org
dc.publisher.placeUnited States
dc.relation.ispartofChest
dc.relation.referencesReferences in Scopus
dc.subject.meshAdult
dc.subject.meshAnxiety - epidemiology
dc.subject.meshAsthma - epidemiology - prevention & control - psychology
dc.subject.meshComorbidity
dc.subject.meshFemale
dc.subject.meshGastroesophageal Reflux - epidemiology - psychology
dc.subject.meshHealth Status Indicators
dc.subject.meshHumans
dc.subject.meshMale
dc.subject.meshMiddle Aged
dc.subject.meshPrevalence
dc.subject.meshQuality of Life
dc.titleGastroesophageal reflux disease is associated with poor asthma control, quality of life, and psychological status in Chinese asthma patients
dc.typeArticle
Author Affiliations
  1. The University of Hong Kong