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Article: Normal values of 24-hour combined esophageal multichannel intraluminal impedance and pH monitoring in the Chinese population

TitleNormal values of 24-hour combined esophageal multichannel intraluminal impedance and pH monitoring in the Chinese population
Authors
Issue Date2009
PublisherS Karger AG. The Journal's web site is located at http://www.karger.com/DIG
Citation
Digestion, 2009, v. 79 n. 2, p. 109-114 How to Cite?
AbstractBackground: There is a lack of data on combined esophageal multichannel intraluminal impedance and pH (MII-pH) monitoring in the Chinese population. Goals: To define the normal range and compare the parameters to those of the Western population. Study: Healthy volunteers were recruited and underwent 24-hour ambulatory combined MII-pH monitoring. Gastroesophageal reflux episodes were detected and characterized by pH (acidic, weakly acidic and weakly alkaline reflux) and composition (liquid, mixed and gas reflux). Results: Seventy healthy volunteers (male:female 33:37) were recruited. The median and 95th percentile number of the total reflux episodes over 24 h in the Chinese population was 40 and 75, respectively, whereas the corresponding numbers of acidic, weakly acidic and weakly alkaline reflux episodes were 22 and 54, 16 and 40, and 0 and 4, respectively. Among all reflux episodes 53.3% were acidic, 44.7% were weakly acidic, and 2% weakly alkaline. More than half (52.4%) of the reflux episodes were mixed, 37.2% were liquid, and 10.4% were gas. A total of 26.6% of reflux episodes reached 15 cm above the lower esophageal sphincter. Male gender was associated with an increased number of acid, liquid, mixed and proximal reflux episodes (p < 0.05). Conclusions: This study provides normal values for the Chinese population. Differences between genders in impedance parameters required caution during data interpretation. The number of reflux episodes in the Chinese population was similar to that in the Western population. Copyright © 2009 S. Karger AG, Basel.
Persistent Identifierhttp://hdl.handle.net/10722/59281
ISSN
2015 Impact Factor: 1.884
2015 SCImago Journal Rankings: 0.953
ISI Accession Number ID
Funding AgencyGrant Number
Shun Tak District Min Yuen Tong Gastroenterology Research Fund, University of Hong Kong, Hong Kong
Funding Information:

This project was partially sponsored by Shun Tak District Min Yuen Tong Gastroenterology Research Fund, University of Hong Kong, Hong Kong.

References

 

DC FieldValueLanguage
dc.contributor.authorXiao, YLen_HK
dc.contributor.authorLin, JKen_HK
dc.contributor.authorCheung, TKen_HK
dc.contributor.authorWong, NYHen_HK
dc.contributor.authorYang, Len_HK
dc.contributor.authorHung, IFNen_HK
dc.contributor.authorWong, BCYen_HK
dc.contributor.authorChen, MHen_HK
dc.date.accessioned2010-05-31T03:46:55Z-
dc.date.available2010-05-31T03:46:55Z-
dc.date.issued2009en_HK
dc.identifier.citationDigestion, 2009, v. 79 n. 2, p. 109-114en_HK
dc.identifier.issn0012-2823en_HK
dc.identifier.urihttp://hdl.handle.net/10722/59281-
dc.description.abstractBackground: There is a lack of data on combined esophageal multichannel intraluminal impedance and pH (MII-pH) monitoring in the Chinese population. Goals: To define the normal range and compare the parameters to those of the Western population. Study: Healthy volunteers were recruited and underwent 24-hour ambulatory combined MII-pH monitoring. Gastroesophageal reflux episodes were detected and characterized by pH (acidic, weakly acidic and weakly alkaline reflux) and composition (liquid, mixed and gas reflux). Results: Seventy healthy volunteers (male:female 33:37) were recruited. The median and 95th percentile number of the total reflux episodes over 24 h in the Chinese population was 40 and 75, respectively, whereas the corresponding numbers of acidic, weakly acidic and weakly alkaline reflux episodes were 22 and 54, 16 and 40, and 0 and 4, respectively. Among all reflux episodes 53.3% were acidic, 44.7% were weakly acidic, and 2% weakly alkaline. More than half (52.4%) of the reflux episodes were mixed, 37.2% were liquid, and 10.4% were gas. A total of 26.6% of reflux episodes reached 15 cm above the lower esophageal sphincter. Male gender was associated with an increased number of acid, liquid, mixed and proximal reflux episodes (p < 0.05). Conclusions: This study provides normal values for the Chinese population. Differences between genders in impedance parameters required caution during data interpretation. The number of reflux episodes in the Chinese population was similar to that in the Western population. Copyright © 2009 S. Karger AG, Basel.en_HK
dc.languageengen_HK
dc.publisherS Karger AG. The Journal's web site is located at http://www.karger.com/DIGen_HK
dc.relation.ispartofDigestionen_HK
dc.rightsDigestion. Copyright © S Karger AG.en_HK
dc.subject.meshAdulten_HK
dc.subject.meshAgeden_HK
dc.subject.meshAsian Continental Ancestry Groupen_HK
dc.subject.meshChinaen_HK
dc.subject.meshElectric Impedanceen_HK
dc.subject.meshEsophageal pH Monitoringen_HK
dc.subject.meshFemaleen_HK
dc.subject.meshGastroesophageal Reflux - diagnosisen_HK
dc.subject.meshHumansen_HK
dc.subject.meshMaleen_HK
dc.subject.meshMiddle Ageden_HK
dc.subject.meshReference Valuesen_HK
dc.subject.meshYoung Adulten_HK
dc.titleNormal values of 24-hour combined esophageal multichannel intraluminal impedance and pH monitoring in the Chinese populationen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0012-2823&volume=79&issue=2&spage=109&epage=114&date=2009&atitle=Normal+values+of+24-Hour+combined+esophageal+multichannel+intraluminal+impedance+and+pH+monitoring+in+the+chinese+populationen_HK
dc.identifier.emailHung, IFN:ivanhung@hkucc.hku.hken_HK
dc.identifier.emailWong, BCY:bcywong@hku.hken_HK
dc.identifier.authorityHung, IFN=rp00508en_HK
dc.identifier.authorityWong, BCY=rp00429en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1159/000209220en_HK
dc.identifier.pmid19295211-
dc.identifier.scopuseid_2-s2.0-62349110379en_HK
dc.identifier.hkuros159009en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-62349110379&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume79en_HK
dc.identifier.issue2en_HK
dc.identifier.spage109en_HK
dc.identifier.epage114en_HK
dc.identifier.isiWOS:000264943600007-
dc.publisher.placeSwitzerlanden_HK
dc.identifier.scopusauthoridXiao, YL=23500436000en_HK
dc.identifier.scopusauthoridLin, JK=8065241700en_HK
dc.identifier.scopusauthoridCheung, TK=7103334158en_HK
dc.identifier.scopusauthoridWong, NYH=7202836655en_HK
dc.identifier.scopusauthoridYang, L=7406275448en_HK
dc.identifier.scopusauthoridHung, IFN=7006103457en_HK
dc.identifier.scopusauthoridWong, BCY=7402023340en_HK
dc.identifier.scopusauthoridChen, MH=8642044500en_HK

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