Article: Disulfide bond creates a small connecting loop in aminoxy peptide backbone

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TitleDisulfide bond creates a small connecting loop in aminoxy peptide backbone
AuthorsYang, D1 2
Liu, GJ2
Jiao, ZG2
Zhang, DW2
Luo, Z2
Song, KS1
Chen, MQ2
KeywordsAminoxy peptides
Disulfide bonds
Foldamers
Loop motifs
Peptides
Protein folding
Issue Date2008
PublisherWiley - V C H Verlag GmbH & Co KGaA. The Journal's web site is located at http://www.wiley-vch.de/home/chemistry
CitationChemistry - A European Journal, 2008, v. 14 n. 33, p. 10297-10302 [How to Cite?]
DOI: http://dx.doi.org/10.1002/chem.200800095
AbstractDisulfide-bond formation between the side chains of cysteine-cysteine pairs is often critical to the folding behavior, stability, and functionality of proteins. In this paper, we report that sulfur atoms can be introduced into the amide groups of aminoxy peptides to form a novel type of disulfide bridge, which creates a connecting loop in the peptide backbone. © 2008 Wiley-VCH Verlag GmbH & Co. KGaA.
ISSN0947-6539
2011 Impact Factor: 5.925
2011 SCImago Journal Rankings: 0.455
DOIhttp://dx.doi.org/10.1002/chem.200800095
ISI Accession Number IDWOS:000261559400018
Funding AgencyGrant Number
Fudan University, the National Natural Science Foundation of China20202001
Fok Ying Tung Education Foundation94023
HKU-Fudan Joint Laboratory on Molecular Design and SynthesisFIKU 7654/06M
Funding Information:

This work was supported by Fudan University, the National Natural Science Foundation of China (project no. 20202001), the Fok Ying Tung Education Foundation (project no. 94023), the HKU-Fudan Joint Laboratory on Molecular Design and Synthesis, and the Research Grants Council of Hong Kong (project no. FIKU 7654/06M). D.-W. Z. would like to thank Fudan University for the conferment of the Century Star Award.

ReferencesReferences in Scopus
DC Field
Value
dc.contributor.authorYang, D
dc.contributor.authorLiu, GJ
dc.contributor.authorJiao, ZG
dc.contributor.authorZhang, DW
dc.contributor.authorLuo, Z
dc.contributor.authorSong, KS
dc.contributor.authorChen, MQ
dc.date.accessioned2010-05-31T03:29:32Z
dc.date.available2010-05-31T03:29:32Z
dc.date.issued2008
dc.description.abstractDisulfide-bond formation between the side chains of cysteine-cysteine pairs is often critical to the folding behavior, stability, and functionality of proteins. In this paper, we report that sulfur atoms can be introduced into the amide groups of aminoxy peptides to form a novel type of disulfide bridge, which creates a connecting loop in the peptide backbone. © 2008 Wiley-VCH Verlag GmbH & Co. KGaA.
dc.description.natureLink_to_subscribed_fulltext
dc.identifier.citationChemistry - A European Journal, 2008, v. 14 n. 33, p. 10297-10302 [How to Cite?]
DOI: http://dx.doi.org/10.1002/chem.200800095
dc.identifier.doihttp://dx.doi.org/10.1002/chem.200800095
dc.identifier.epage10302
dc.identifier.hkuros161374
dc.identifier.isiWOS:000261559400018
Funding AgencyGrant Number
Fudan University, the National Natural Science Foundation of China20202001
Fok Ying Tung Education Foundation94023
HKU-Fudan Joint Laboratory on Molecular Design and SynthesisFIKU 7654/06M
Funding Information:

This work was supported by Fudan University, the National Natural Science Foundation of China (project no. 20202001), the Fok Ying Tung Education Foundation (project no. 94023), the HKU-Fudan Joint Laboratory on Molecular Design and Synthesis, and the Research Grants Council of Hong Kong (project no. FIKU 7654/06M). D.-W. Z. would like to thank Fudan University for the conferment of the Century Star Award.

dc.identifier.issn0947-6539
2011 Impact Factor: 5.925
2011 SCImago Journal Rankings: 0.455
dc.identifier.issue33
dc.identifier.openurl
dc.identifier.pmid18846598
dc.identifier.scopuseid_2-s2.0-56349094706
dc.identifier.spage10297
dc.identifier.urihttp://hdl.handle.net/10722/58394
dc.identifier.volume14
dc.languageeng
dc.publisherWiley - V C H Verlag GmbH & Co KGaA. The Journal's web site is located at http://www.wiley-vch.de/home/chemistry
dc.publisher.placeGermany
dc.relation.ispartofChemistry - A European Journal
dc.relation.referencesReferences in Scopus
dc.subject.meshAmines - chemistry
dc.subject.meshDisulfides - chemistry
dc.subject.meshOxides - chemistry
dc.subject.meshPeptides - chemical synthesis - chemistry
dc.subject.meshSpectrophotometry
dc.subjectAminoxy peptides
dc.subjectDisulfide bonds
dc.subjectFoldamers
dc.subjectLoop motifs
dc.subjectPeptides
dc.subjectProtein folding
dc.titleDisulfide bond creates a small connecting loop in aminoxy peptide backbone
dc.typeArticle
Author Affiliations
  1. The University of Hong Kong
  2. Fudan University