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Article: Gold(III) (C^N) complex-catalyzed synthesis of propargylamines via a three-component coupling reaction of aldehydes, amines and alkynes

TitleGold(III) (C^N) complex-catalyzed synthesis of propargylamines via a three-component coupling reaction of aldehydes, amines and alkynes
Authors
KeywordsGold(III) catalyst
Prolinol derivatives
Propargylamines
Three-component coupling reaction
Issue Date2009
PublisherElsevier SA. The Journal's web site is located at http://www.elsevier.com/locate/jorganchem
Citation
Journal Of Organometallic Chemistry, 2009, v. 694 n. 4, p. 583-591 How to Cite?
AbstractPropargylamines are synthesized in high yields via a gold(III) (C^N) complex-catalyzed three-component coupling reaction of aldehydes, amines and alkynes in water at 40 °C. Excellent diastereoselectivities (up to 99:1) have been achieved when chiral prolinol derivatives are employed as the amine component. Notably, the [Au(C^N)Cl2] complex (N^CH = 2-phenylpyridine) could be repeatedly used for 10 reaction cycles, leading to an overall turnover number of 812. © 2008 Elsevier B.V. All rights reserved.
Persistent Identifierhttp://hdl.handle.net/10722/58333
ISSN
2021 Impact Factor: 2.345
2020 SCImago Journal Rankings: 0.484
ISI Accession Number ID
Funding AgencyGrant Number
Hong Kong Research Grants CouncilPolyU 7052/07P
PolyU Departmental General Research Funds
The University of Hong Kong
University Grants Committee of the Hong Kong SAR of ChinaAoE/P-10/01
Funding Information:

This work was supported by the Hong Kong Research Grants Council (PolyU 7052/07P), PolyU Departmental General Research Funds, The University of Hong Kong (University Development Fund), and the University Grants Committee of the Hong Kong SAR of China (Area of Excellence Scheme, AoE/P-10/01).

References
Grants

 

DC FieldValueLanguage
dc.contributor.authorLo, VKYen_HK
dc.contributor.authorKung, KKYen_HK
dc.contributor.authorWong, MKen_HK
dc.contributor.authorChe, CMen_HK
dc.date.accessioned2010-05-31T03:28:28Z-
dc.date.available2010-05-31T03:28:28Z-
dc.date.issued2009en_HK
dc.identifier.citationJournal Of Organometallic Chemistry, 2009, v. 694 n. 4, p. 583-591en_HK
dc.identifier.issn0022-328Xen_HK
dc.identifier.urihttp://hdl.handle.net/10722/58333-
dc.description.abstractPropargylamines are synthesized in high yields via a gold(III) (C^N) complex-catalyzed three-component coupling reaction of aldehydes, amines and alkynes in water at 40 °C. Excellent diastereoselectivities (up to 99:1) have been achieved when chiral prolinol derivatives are employed as the amine component. Notably, the [Au(C^N)Cl2] complex (N^CH = 2-phenylpyridine) could be repeatedly used for 10 reaction cycles, leading to an overall turnover number of 812. © 2008 Elsevier B.V. All rights reserved.en_HK
dc.languageengen_HK
dc.publisherElsevier SA. The Journal's web site is located at http://www.elsevier.com/locate/jorganchemen_HK
dc.relation.ispartofJournal of Organometallic Chemistryen_HK
dc.subjectGold(III) catalysten_HK
dc.subjectProlinol derivativesen_HK
dc.subjectPropargylaminesen_HK
dc.subjectThree-component coupling reactionen_HK
dc.titleGold(III) (C^N) complex-catalyzed synthesis of propargylamines via a three-component coupling reaction of aldehydes, amines and alkynesen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0022-328X&volume=694&spage=583&epage=591&date=2009&atitle=Gold(III)+(C^N)+Complex-Catalyzed+Synthesis+of+Propargylamines+via+a+Three-Component+Coupling+Reaction+of+Aldehydes,+Amines+and+Alkynes+en_HK
dc.identifier.emailChe, CM:cmche@hku.hken_HK
dc.identifier.authorityChe, CM=rp00670en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/j.jorganchem.2008.12.008en_HK
dc.identifier.scopuseid_2-s2.0-58649115594en_HK
dc.identifier.hkuros155987en_HK
dc.identifier.hkuros177355-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-58649115594&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume694en_HK
dc.identifier.issue4en_HK
dc.identifier.spage583en_HK
dc.identifier.epage591en_HK
dc.identifier.isiWOS:000262887200017-
dc.publisher.placeSwitzerlanden_HK
dc.relation.projectInstitute of molecular technology for drug discovery and synthesis-
dc.identifier.scopusauthoridLo, VKY=13406071200en_HK
dc.identifier.scopusauthoridKung, KKY=25959176500en_HK
dc.identifier.scopusauthoridWong, MK=7403908449en_HK
dc.identifier.scopusauthoridChe, CM=7102442791en_HK
dc.identifier.issnl0022-328X-

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