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Article: Adjuvant analgesics in neuropathic pain

TitleAdjuvant analgesics in neuropathic pain
Authors
Issue Date2009
PublisherCambridge University Press. The Journal's web site is located at http://journals.cambridge.org/action/displayJournal?jid=EJA
Citation
European Journal Of Anaesthesiology, 2009, v. 26 n. 2, p. 96-100 How to Cite?
AbstractConventional analgesics have limited efficacy in the management of neuropathic pain. An adjuvant analgesic is a drug that has a primary nonpain indication but which may be analgesic in certain circumstances, and many of these have established a role in the pharmacological treatment of neuropathic pain. The number needed to treat is an indirect statistical measure that can be used to compare relative efficacy of different adjuvant analgesics and, from this, there is currently insufficient evidence to suggest that any one adjuvant analgesic has absolute advantages over another. Analgesic efficacy, tolerability, safety/toxicity, drug interactions, ease of use, and cost-effectiveness are essential factors that guide the selection of an adjuvant analgesic. Cost-effectiveness data are absent for the vast majority of these drugs. Pharmacological treatments should be used as part of a multimodal therapeutic programme for the management of neuropathic pain. © 2009 Copyright European Society of Anaesthesiology.
Persistent Identifierhttp://hdl.handle.net/10722/58176
ISSN
2015 Impact Factor: 3.634
2015 SCImago Journal Rankings: 0.999
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorKong, VKFen_HK
dc.contributor.authorIrwin, MGen_HK
dc.date.accessioned2010-05-31T03:25:10Z-
dc.date.available2010-05-31T03:25:10Z-
dc.date.issued2009en_HK
dc.identifier.citationEuropean Journal Of Anaesthesiology, 2009, v. 26 n. 2, p. 96-100en_HK
dc.identifier.issn0265-0215en_HK
dc.identifier.urihttp://hdl.handle.net/10722/58176-
dc.description.abstractConventional analgesics have limited efficacy in the management of neuropathic pain. An adjuvant analgesic is a drug that has a primary nonpain indication but which may be analgesic in certain circumstances, and many of these have established a role in the pharmacological treatment of neuropathic pain. The number needed to treat is an indirect statistical measure that can be used to compare relative efficacy of different adjuvant analgesics and, from this, there is currently insufficient evidence to suggest that any one adjuvant analgesic has absolute advantages over another. Analgesic efficacy, tolerability, safety/toxicity, drug interactions, ease of use, and cost-effectiveness are essential factors that guide the selection of an adjuvant analgesic. Cost-effectiveness data are absent for the vast majority of these drugs. Pharmacological treatments should be used as part of a multimodal therapeutic programme for the management of neuropathic pain. © 2009 Copyright European Society of Anaesthesiology.en_HK
dc.languageengen_HK
dc.publisherCambridge University Press. The Journal's web site is located at http://journals.cambridge.org/action/displayJournal?jid=EJAen_HK
dc.relation.ispartofEuropean Journal of Anaesthesiologyen_HK
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.subject.meshAdjuvants, Pharmaceutic - therapeutic useen_HK
dc.subject.meshAnalgesics - therapeutic useen_HK
dc.subject.meshAnimalsen_HK
dc.subject.meshAntidepressive Agents - therapeutic useen_HK
dc.subject.meshChronic Disease - drug therapyen_HK
dc.subject.meshCranial Nerve Diseases - drug therapyen_HK
dc.subject.meshHumansen_HK
dc.subject.meshPain - drug therapyen_HK
dc.titleAdjuvant analgesics in neuropathic painen_HK
dc.typeArticleen_HK
dc.identifier.emailIrwin, MG:mgirwin@hku.hken_HK
dc.identifier.authorityIrwin, MG=rp00390en_HK
dc.description.naturepublished_or_final_version-
dc.identifier.doi10.1097/EJA.0b013e328318c706en_HK
dc.identifier.pmid19142081-
dc.identifier.scopuseid_2-s2.0-61549108581en_HK
dc.identifier.hkuros160847en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-61549108581&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume26en_HK
dc.identifier.issue2en_HK
dc.identifier.spage96en_HK
dc.identifier.epage100en_HK
dc.identifier.isiWOS:000263088300002-
dc.publisher.placeUnited Kingdomen_HK

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