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Article: Nucleation of strontium-substituted apatite

TitleNucleation of strontium-substituted apatite
Authors
Issue Date2009
PublisherAmerican Chemical Society. The Journal's web site is located at http://pubs.acs.org/crystal
Citation
Crystal Growth And Design, 2009, v. 9 n. 8, p. 3342-3345 How to Cite?
AbstractStrontium plays an important role in the treatment of osteoporosis, but the detailed chemistry is still in doubt. In particular, the effect of strontium on the stability of natural bone is not well understood. To simulate the context of strontium intake as a drug, simulated body fluid solution containing various strontium concentrations [Sr] was seeded with biological apatite. No significant incorporation of strontium in the resulting apatite was detected for [Sr] < 0.1 mM, but crystal morphology changed dramatically and crystallinity increased for [Sr] ≥ 0.3 mM due to the formation of strontium-substituted apatite, with substitution increasing with an increase of solution [Sr]. © 2009 American Chemical Society.
Persistent Identifierhttp://hdl.handle.net/10722/58153
ISSN
2015 Impact Factor: 4.425
2015 SCImago Journal Rankings: 1.328
ISI Accession Number ID
Funding AgencyGrant Number
Hong Kong ITFGHP/009/06
HKRGCHKU7147/07E
Funding Information:

This study was supported by Hong Kong ITF GHP/009/06 and HKRGC (HKU7147/07E). The authors thank Frankie Chan for his assistance in SEM analysis and Guofeng Chen for XRD analysis.

References
Grants

 

DC FieldValueLanguage
dc.contributor.authorPan, HBen_HK
dc.contributor.authorLi, ZYen_HK
dc.contributor.authorWang, Ten_HK
dc.contributor.authorLam, WMen_HK
dc.contributor.authorWong, CTen_HK
dc.contributor.authorDarvell, BWen_HK
dc.contributor.authorLuk, KDKen_HK
dc.contributor.authorHu, Yen_HK
dc.contributor.authorLu, WWen_HK
dc.date.accessioned2010-05-31T03:24:42Z-
dc.date.available2010-05-31T03:24:42Z-
dc.date.issued2009en_HK
dc.identifier.citationCrystal Growth And Design, 2009, v. 9 n. 8, p. 3342-3345en_HK
dc.identifier.issn1528-7483en_HK
dc.identifier.urihttp://hdl.handle.net/10722/58153-
dc.description.abstractStrontium plays an important role in the treatment of osteoporosis, but the detailed chemistry is still in doubt. In particular, the effect of strontium on the stability of natural bone is not well understood. To simulate the context of strontium intake as a drug, simulated body fluid solution containing various strontium concentrations [Sr] was seeded with biological apatite. No significant incorporation of strontium in the resulting apatite was detected for [Sr] < 0.1 mM, but crystal morphology changed dramatically and crystallinity increased for [Sr] ≥ 0.3 mM due to the formation of strontium-substituted apatite, with substitution increasing with an increase of solution [Sr]. © 2009 American Chemical Society.en_HK
dc.languageengen_HK
dc.publisherAmerican Chemical Society. The Journal's web site is located at http://pubs.acs.org/crystalen_HK
dc.relation.ispartofCrystal Growth and Designen_HK
dc.titleNucleation of strontium-substituted apatiteen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1528-7483&volume=9&issue=8&spage=3342&epage=3345&date=2009&atitle=Nucleation+of+strontium-substituted+apatite-
dc.identifier.emailPan, HB: haobo@hku.hken_HK
dc.identifier.emailDarvell, BW: b.w.darvell@hku.hken_HK
dc.identifier.emailLuk, KDK: hcm21000@hku.hken_HK
dc.identifier.emailHu, Y: yhud@hku.hken_HK
dc.identifier.emailLu, WW: wwlu@hku.hken_HK
dc.identifier.authorityPan, HB=rp01564en_HK
dc.identifier.authorityDarvell, BW=rp00007en_HK
dc.identifier.authorityLuk, KDK=rp00333en_HK
dc.identifier.authorityHu, Y=rp00432en_HK
dc.identifier.authorityLu, WW=rp00411en_HK
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1021/cg900038ken_HK
dc.identifier.scopuseid_2-s2.0-68949088491en_HK
dc.identifier.hkuros180197en_HK
dc.identifier.hkuros163514-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-68949088491&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume9en_HK
dc.identifier.issue8en_HK
dc.identifier.spage3342en_HK
dc.identifier.epage3345en_HK
dc.identifier.isiWOS:000268537200002-
dc.publisher.placeUnited Statesen_HK
dc.relation.projectOptimization and commercialization of strontium containing bioactive bone cement for various orthopaedic applications-
dc.identifier.scopusauthoridPan, HB=7403295092en_HK
dc.identifier.scopusauthoridLi, ZY=35784563200en_HK
dc.identifier.scopusauthoridWang, T=11840122500en_HK
dc.identifier.scopusauthoridLam, WM=13403256300en_HK
dc.identifier.scopusauthoridWong, CT=7404954512en_HK
dc.identifier.scopusauthoridDarvell, BW=7005953926en_HK
dc.identifier.scopusauthoridLuk, KDK=7201921573en_HK
dc.identifier.scopusauthoridHu, Y=7407116091en_HK
dc.identifier.scopusauthoridLu, WW=7404215221en_HK

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