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Article: Biofilm lifestyle of Candida: A mini review

TitleBiofilm lifestyle of Candida: A mini review
Authors
Issue Date2008
PublisherWiley-Blackwell Publishing, Inc.. The Journal's web site is located at http://www.wiley.com/bw/journal.asp?ref=1354-523X&site=1
Citation
Oral Diseases, 2008, v. 14 n. 7, p. 582-590 How to Cite?
AbstractCandida is the major fungal pathogen of humans causing a variety of afflictions ranging from superficial mucosal diseases to deep seated mycoses. Biofilm formation is a major virulence factor in the pathogenicity of Candida, and Candida biofilms are difficult to eradicate especially because of their very high antifungal resistance. Consequently, research into the pathogenicity of Candida has focused on the prevention and management of biofilm development, their architecture, and antifungal resistance. Although studies have shed some light, molecular mechanisms that govern biofilm formation and pathogenicity still await full clarification. This review outlines the key features of what is currently known of Candida biofilm development, regulation and antifungal resistance and, their proteomics. © 2007 The Authors.
Persistent Identifierhttp://hdl.handle.net/10722/58125
ISSN
2015 Impact Factor: 2.0
2015 SCImago Journal Rankings: 0.828
ISI Accession Number ID
Funding AgencyGrant Number
Research Grants Council of Hong Kong CERGHKU 7624/06M
Funding Information:

We wish to acknowledge gratefully the editorial support provided by Dr Trevor Lane PhD ( Oxon), and the financial support from the Research Grants Council of Hong Kong CERG grant No HKU 7624/06M of LPS. We are grateful to Dr. Bernard Low and Dr. Thein ZM, Faculty of Dentistry, The University of Hong Kong for Figures 1 and 2 respectively.

References
Grants

 

DC FieldValueLanguage
dc.contributor.authorSeneviratne, CJen_HK
dc.contributor.authorJin, Len_HK
dc.contributor.authorSamaranayake, LPen_HK
dc.date.accessioned2010-05-31T03:24:13Z-
dc.date.available2010-05-31T03:24:13Z-
dc.date.issued2008en_HK
dc.identifier.citationOral Diseases, 2008, v. 14 n. 7, p. 582-590en_HK
dc.identifier.issn1354-523Xen_HK
dc.identifier.urihttp://hdl.handle.net/10722/58125-
dc.description.abstractCandida is the major fungal pathogen of humans causing a variety of afflictions ranging from superficial mucosal diseases to deep seated mycoses. Biofilm formation is a major virulence factor in the pathogenicity of Candida, and Candida biofilms are difficult to eradicate especially because of their very high antifungal resistance. Consequently, research into the pathogenicity of Candida has focused on the prevention and management of biofilm development, their architecture, and antifungal resistance. Although studies have shed some light, molecular mechanisms that govern biofilm formation and pathogenicity still await full clarification. This review outlines the key features of what is currently known of Candida biofilm development, regulation and antifungal resistance and, their proteomics. © 2007 The Authors.en_HK
dc.languageengen_HK
dc.publisherWiley-Blackwell Publishing, Inc.. The Journal's web site is located at http://www.wiley.com/bw/journal.asp?ref=1354-523X&site=1en_HK
dc.relation.ispartofOral Diseasesen_HK
dc.subject.meshAntifungal Agents - pharmacologyen_HK
dc.subject.meshBiofilms - drug effects - growth & developmenten_HK
dc.subject.meshCandida - drug effects - growth & developmenten_HK
dc.subject.meshDrug Resistance, Fungalen_HK
dc.subject.meshProteomeen_HK
dc.titleBiofilm lifestyle of Candida: A mini reviewen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1354-523X&volume=14&spage=582&epage=590&date=2008&atitle=Biofilm+lifestyle+of+Candida:+a+mini+reviewen_HK
dc.identifier.emailSeneviratne, CJ:jaya@hku.hken_HK
dc.identifier.emailJin, L:ljjin@hkucc.hku.hken_HK
dc.identifier.emailSamaranayake, LP:lakshman@hku.hken_HK
dc.identifier.authoritySeneviratne, CJ=rp01372en_HK
dc.identifier.authorityJin, L=rp00028en_HK
dc.identifier.authoritySamaranayake, LP=rp00023en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1111/j.1601-0825.2007.01424.xen_HK
dc.identifier.pmid19076549-
dc.identifier.scopuseid_2-s2.0-53149143909en_HK
dc.identifier.hkuros152516en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-53149143909&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume14en_HK
dc.identifier.issue7en_HK
dc.identifier.spage582en_HK
dc.identifier.epage590en_HK
dc.identifier.isiWOS:000259684700002-
dc.publisher.placeUnited Statesen_HK
dc.relation.projectCandida biofilms: molecular mechanisms and clinical implications-
dc.identifier.scopusauthoridSeneviratne, CJ=6701897753en_HK
dc.identifier.scopusauthoridJin, L=7403328850en_HK
dc.identifier.scopusauthoridSamaranayake, LP=7102761002en_HK
dc.identifier.citeulike3374126-

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