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Article: Does economic development contribute to sex differences in ischaemic heart disease mortality? Hong Kong as a natural experiment using a case-control study

TitleDoes economic development contribute to sex differences in ischaemic heart disease mortality? Hong Kong as a natural experiment using a case-control study
Authors
Issue Date2008
PublisherBioMed Central Ltd. The Journal's web site is located at http://www.biomedcentral.com/bmcpublichealth/
Citation
Bmc Public Health, 2008, v. 8 How to Cite?
AbstractBackground. The male excess risk of premature ischemic heart disease (IHD) mortality may be partially due to an unknown macro-environmental influence associated with economic development. We examined whether excess male risk of IHD mortality was higher with birth in an economically developed environment. Methods. We used multivariable logistic regression in a population-based case-control study of all adult deaths in Hong Kong Chinese in 1998 to compare sex differences in IHD mortality (1,189 deaths in men, 1,035 deaths in women and 20,842 controls) between Hong Kong residents born in economically developed Hong Kong or in contemporaneously undeveloped Guangdong province in China. Results. Younger (35-64 years) native-born Hong Kong men had a higher risk of IHD death than such women (odds ratio 2.91, 95% confidence interval 1.66 to 5.13), adjusted for age, socio-economic status and lifestyle. There was no such sex difference in Hong Kong residents who had migrated from Guangdong. There were no sex differences in pneumonia deaths by birth place. Conclusion. Most of these people migrated as young adults; we speculate that environmentally mediated differences in pubertal maturation (when the male disadvantage in lipids and fat patterning emerges) may contribute to excess male premature IHD mortality in developed environments. © 2008 Schooling et al; licensee BioMed Central Ltd.
Persistent Identifierhttp://hdl.handle.net/10722/57377
ISSN
2015 Impact Factor: 2.209
2015 SCImago Journal Rankings: 1.372
PubMed Central ID
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorSchooling, CMen_HK
dc.contributor.authorLam, THen_HK
dc.contributor.authorHo, SYen_HK
dc.contributor.authorMak, KHen_HK
dc.contributor.authorLeung, GMen_HK
dc.date.accessioned2010-04-12T01:34:38Z-
dc.date.available2010-04-12T01:34:38Z-
dc.date.issued2008en_HK
dc.identifier.citationBmc Public Health, 2008, v. 8en_HK
dc.identifier.issn1471-2458en_HK
dc.identifier.urihttp://hdl.handle.net/10722/57377-
dc.description.abstractBackground. The male excess risk of premature ischemic heart disease (IHD) mortality may be partially due to an unknown macro-environmental influence associated with economic development. We examined whether excess male risk of IHD mortality was higher with birth in an economically developed environment. Methods. We used multivariable logistic regression in a population-based case-control study of all adult deaths in Hong Kong Chinese in 1998 to compare sex differences in IHD mortality (1,189 deaths in men, 1,035 deaths in women and 20,842 controls) between Hong Kong residents born in economically developed Hong Kong or in contemporaneously undeveloped Guangdong province in China. Results. Younger (35-64 years) native-born Hong Kong men had a higher risk of IHD death than such women (odds ratio 2.91, 95% confidence interval 1.66 to 5.13), adjusted for age, socio-economic status and lifestyle. There was no such sex difference in Hong Kong residents who had migrated from Guangdong. There were no sex differences in pneumonia deaths by birth place. Conclusion. Most of these people migrated as young adults; we speculate that environmentally mediated differences in pubertal maturation (when the male disadvantage in lipids and fat patterning emerges) may contribute to excess male premature IHD mortality in developed environments. © 2008 Schooling et al; licensee BioMed Central Ltd.en_HK
dc.languageengen_HK
dc.publisherBioMed Central Ltd. The Journal's web site is located at http://www.biomedcentral.com/bmcpublichealth/en_HK
dc.relation.ispartofBMC Public Healthen_HK
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.rightsB M C Public Health. Copyright © BioMed Central Ltd.en_HK
dc.subject.meshCase-Control Studiesen_HK
dc.subject.meshEmigration and Immigrationen_HK
dc.subject.meshMyocardial Ischemia - economics - etiology - mortalityen_HK
dc.subject.meshPuberty - physiologyen_HK
dc.subject.meshSocioeconomic Factorsen_HK
dc.titleDoes economic development contribute to sex differences in ischaemic heart disease mortality? Hong Kong as a natural experiment using a case-control studyen_HK
dc.typeArticleen_HK
dc.identifier.emailSchooling, CM:cms1@hkucc.hku.hken_HK
dc.identifier.emailLam, TH:hrmrlth@hkucc.hku.hken_HK
dc.identifier.emailHo, SY:syho@hku.hken_HK
dc.identifier.emailLeung, GM:gmleung@hku.hken_HK
dc.identifier.authoritySchooling, CM=rp00504en_HK
dc.identifier.authorityLam, TH=rp00326en_HK
dc.identifier.authorityHo, SY=rp00427en_HK
dc.identifier.authorityLeung, GM=rp00460en_HK
dc.description.naturepublished_or_final_versionen_HK
dc.identifier.doi10.1186/1471-2458-8-32en_HK
dc.identifier.pmid18221504-
dc.identifier.pmcidPMC2245924en_HK
dc.identifier.scopuseid_2-s2.0-39149124463en_HK
dc.identifier.hkuros140709-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-39149124463&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume8en_HK
dc.identifier.isiWOS:000253422700001-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridSchooling, CM=12808565000en_HK
dc.identifier.scopusauthoridLam, TH=7202522876en_HK
dc.identifier.scopusauthoridHo, SY=7403716884en_HK
dc.identifier.scopusauthoridMak, KH=8623141300en_HK
dc.identifier.scopusauthoridLeung, GM=7007159841en_HK
dc.identifier.citeulike2313589-

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