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Article: Sjögren's syndrome sufferers have increased oral yeast levels despite regular dental care
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TitleSjögren's syndrome sufferers have increased oral yeast levels despite regular dental care
 
AuthorsLeung, KCM1
McMillan, AS1
Cheung, BPK1
Leung, WK1 2
 
KeywordsCandida albicans
Candidiasis, oral
Dental plaque
Mycology
Sjögren's syndrome
Xerostomia
 
Issue Date2008
 
PublisherWiley-Blackwell Publishing, Inc.. The Journal's web site is located at http://www.wiley.com/bw/journal.asp?ref=1354-523X&site=1
 
CitationOral Diseases, 2008, v. 14 n. 2, p. 163-173 [How to Cite?]
DOI: http://dx.doi.org/10.1111/j.1601-0825.2007.01368.x
 
AbstractAim: To investigate the prevalence and quantity of oral yeasts and their association with oral candidiasis in Sjögren's syndrome (SS) patients receiving regular dental care. Materials and methods: Yeasts in oral rinse and full-mouth supra-gingival plaque samples from 25 primary SS, 27 secondary SS and 29 control subjects were selectively cultured. All yeasts except single-species isolates were genotyped using pulsed field gel electrophoresis (PFGE). Results: Ten (19%) SS sufferers had symptomless candidiasis. SS subjects had a higher prevalence (73%vs 7%) and quantity of yeasts than controls in both oral rinse and plaque samples (P < 0.05). The prevalence of yeasts in plaque was associated with candidiasis regardless of denture wearing (P ≤ 0.04). Candida albicans was the predominant yeast isolated. PFGE showed 20 (66% of total) C. albicans isolate pairs, i.e. C. albicans species isolated from plaque and oral rinse samples of the same individual, were of closely related genetic clonal types (P < 0.01). Conclusions: Despite effective oral hygiene, more SS subjects than controls had detectable levels of oral yeasts and their presence in supra-gingival plaque was associated with candidiasis. Candida albicans colonized supra-gingival biofilm even in well-maintained SS individuals, posing a challenge to the control of oral candidiasis. © 2007 The Authors.
 
ISSN1354-523X
2013 Impact Factor: 2.404
 
DOIhttp://dx.doi.org/10.1111/j.1601-0825.2007.01368.x
 
ISI Accession Number IDWOS:000253482000011
 
ReferencesReferences in Scopus
 
DC FieldValue
dc.contributor.authorLeung, KCM
 
dc.contributor.authorMcMillan, AS
 
dc.contributor.authorCheung, BPK
 
dc.contributor.authorLeung, WK
 
dc.date.accessioned2009-08-06T03:37:52Z
 
dc.date.available2009-08-06T03:37:52Z
 
dc.date.issued2008
 
dc.description.abstractAim: To investigate the prevalence and quantity of oral yeasts and their association with oral candidiasis in Sjögren's syndrome (SS) patients receiving regular dental care. Materials and methods: Yeasts in oral rinse and full-mouth supra-gingival plaque samples from 25 primary SS, 27 secondary SS and 29 control subjects were selectively cultured. All yeasts except single-species isolates were genotyped using pulsed field gel electrophoresis (PFGE). Results: Ten (19%) SS sufferers had symptomless candidiasis. SS subjects had a higher prevalence (73%vs 7%) and quantity of yeasts than controls in both oral rinse and plaque samples (P < 0.05). The prevalence of yeasts in plaque was associated with candidiasis regardless of denture wearing (P ≤ 0.04). Candida albicans was the predominant yeast isolated. PFGE showed 20 (66% of total) C. albicans isolate pairs, i.e. C. albicans species isolated from plaque and oral rinse samples of the same individual, were of closely related genetic clonal types (P < 0.01). Conclusions: Despite effective oral hygiene, more SS subjects than controls had detectable levels of oral yeasts and their presence in supra-gingival plaque was associated with candidiasis. Candida albicans colonized supra-gingival biofilm even in well-maintained SS individuals, posing a challenge to the control of oral candidiasis. © 2007 The Authors.
 
dc.description.naturepostprint
 
dc.identifier.citationOral Diseases, 2008, v. 14 n. 2, p. 163-173 [How to Cite?]
DOI: http://dx.doi.org/10.1111/j.1601-0825.2007.01368.x
 
dc.identifier.citeulike2436620
 
dc.identifier.doihttp://dx.doi.org/10.1111/j.1601-0825.2007.01368.x
 
dc.identifier.eissn1601-0825
 
dc.identifier.epage173
 
dc.identifier.hkuros140750
 
dc.identifier.isiWOS:000253482000011
 
dc.identifier.issn1354-523X
2013 Impact Factor: 2.404
 
dc.identifier.issue2
 
dc.identifier.openurl
 
dc.identifier.pmid18302677
 
dc.identifier.scopuseid_2-s2.0-39749125122
 
dc.identifier.spage163
 
dc.identifier.urihttp://hdl.handle.net/10722/55451
 
dc.identifier.volume14
 
dc.languageeng
 
dc.publisherWiley-Blackwell Publishing, Inc.. The Journal's web site is located at http://www.wiley.com/bw/journal.asp?ref=1354-523X&site=1
 
dc.publisher.placeUnited States
 
dc.relation.ispartofOral Diseases
 
dc.relation.referencesReferences in Scopus
 
dc.rightsThe definitive version is available at www.blackwell-synergy.com
 
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License
 
dc.subject.meshCandidiasis, Oral - complications - diagnosis - prevention & control
 
dc.subject.meshSjogren's Syndrome - classification - complications - microbiology
 
dc.subject.meshOral Hygiene - methods
 
dc.subject.meshDental Plaque - microbiology
 
dc.subject.meshCandida - isolation & purification
 
dc.subjectCandida albicans
 
dc.subjectCandidiasis, oral
 
dc.subjectDental plaque
 
dc.subjectMycology
 
dc.subjectSjögren's syndrome
 
dc.subjectXerostomia
 
dc.titleSjögren's syndrome sufferers have increased oral yeast levels despite regular dental care
 
dc.typeArticle
 
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Author Affiliations
  1. The University of Hong Kong
  2. Prince Philip Dental Hospital