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- Publisher Website: 10.1111/j.1601-0825.2007.01368.x
- Scopus: eid_2-s2.0-39749125122
- PMID: 18302677
- WOS: WOS:000253482000011
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Article: Sjögren's syndrome sufferers have increased oral yeast levels despite regular dental care
Title | Sjögren's syndrome sufferers have increased oral yeast levels despite regular dental care |
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Authors | |
Keywords | Candida albicans Candidiasis, oral Dental plaque Mycology Sjögren's syndrome Xerostomia |
Issue Date | 2008 |
Publisher | Wiley-Blackwell Publishing, Inc.. The Journal's web site is located at http://www.wiley.com/bw/journal.asp?ref=1354-523X&site=1 |
Citation | Oral Diseases, 2008, v. 14 n. 2, p. 163-173 How to Cite? |
Abstract | Aim: To investigate the prevalence and quantity of oral yeasts and their association with oral candidiasis in Sjögren's syndrome (SS) patients receiving regular dental care. Materials and methods: Yeasts in oral rinse and full-mouth supra-gingival plaque samples from 25 primary SS, 27 secondary SS and 29 control subjects were selectively cultured. All yeasts except single-species isolates were genotyped using pulsed field gel electrophoresis (PFGE). Results: Ten (19%) SS sufferers had symptomless candidiasis. SS subjects had a higher prevalence (73%vs 7%) and quantity of yeasts than controls in both oral rinse and plaque samples (P < 0.05). The prevalence of yeasts in plaque was associated with candidiasis regardless of denture wearing (P ≤ 0.04). Candida albicans was the predominant yeast isolated. PFGE showed 20 (66% of total) C. albicans isolate pairs, i.e. C. albicans species isolated from plaque and oral rinse samples of the same individual, were of closely related genetic clonal types (P < 0.01). Conclusions: Despite effective oral hygiene, more SS subjects than controls had detectable levels of oral yeasts and their presence in supra-gingival plaque was associated with candidiasis. Candida albicans colonized supra-gingival biofilm even in well-maintained SS individuals, posing a challenge to the control of oral candidiasis. © 2007 The Authors. |
Persistent Identifier | http://hdl.handle.net/10722/55451 |
ISSN | 2023 Impact Factor: 2.9 2023 SCImago Journal Rankings: 0.895 |
ISI Accession Number ID | |
References |
DC Field | Value | Language |
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dc.contributor.author | Leung, KCM | en_HK |
dc.contributor.author | McMillan, AS | en_HK |
dc.contributor.author | Cheung, BPK | en_HK |
dc.contributor.author | Leung, WK | en_HK |
dc.date.accessioned | 2009-08-06T03:37:52Z | - |
dc.date.available | 2009-08-06T03:37:52Z | - |
dc.date.issued | 2008 | en_HK |
dc.identifier.citation | Oral Diseases, 2008, v. 14 n. 2, p. 163-173 | en_HK |
dc.identifier.issn | 1354-523X | en_HK |
dc.identifier.uri | http://hdl.handle.net/10722/55451 | - |
dc.description.abstract | Aim: To investigate the prevalence and quantity of oral yeasts and their association with oral candidiasis in Sjögren's syndrome (SS) patients receiving regular dental care. Materials and methods: Yeasts in oral rinse and full-mouth supra-gingival plaque samples from 25 primary SS, 27 secondary SS and 29 control subjects were selectively cultured. All yeasts except single-species isolates were genotyped using pulsed field gel electrophoresis (PFGE). Results: Ten (19%) SS sufferers had symptomless candidiasis. SS subjects had a higher prevalence (73%vs 7%) and quantity of yeasts than controls in both oral rinse and plaque samples (P < 0.05). The prevalence of yeasts in plaque was associated with candidiasis regardless of denture wearing (P ≤ 0.04). Candida albicans was the predominant yeast isolated. PFGE showed 20 (66% of total) C. albicans isolate pairs, i.e. C. albicans species isolated from plaque and oral rinse samples of the same individual, were of closely related genetic clonal types (P < 0.01). Conclusions: Despite effective oral hygiene, more SS subjects than controls had detectable levels of oral yeasts and their presence in supra-gingival plaque was associated with candidiasis. Candida albicans colonized supra-gingival biofilm even in well-maintained SS individuals, posing a challenge to the control of oral candidiasis. © 2007 The Authors. | en_HK |
dc.language | eng | en_HK |
dc.publisher | Wiley-Blackwell Publishing, Inc.. The Journal's web site is located at http://www.wiley.com/bw/journal.asp?ref=1354-523X&site=1 | en_HK |
dc.relation.ispartof | Oral Diseases | en_HK |
dc.rights | The definitive version is available at www.blackwell-synergy.com | en_HK |
dc.subject | Candida albicans | en_HK |
dc.subject | Candidiasis, oral | en_HK |
dc.subject | Dental plaque | en_HK |
dc.subject | Mycology | en_HK |
dc.subject | Sjögren's syndrome | en_HK |
dc.subject | Xerostomia | en_HK |
dc.subject.mesh | Candidiasis, Oral - complications - diagnosis - prevention & control | en_HK |
dc.subject.mesh | Sjogren's Syndrome - classification - complications - microbiology | en_HK |
dc.subject.mesh | Oral Hygiene - methods | en_HK |
dc.subject.mesh | Dental Plaque - microbiology | en_HK |
dc.subject.mesh | Candida - isolation & purification | en_HK |
dc.title | Sjögren's syndrome sufferers have increased oral yeast levels despite regular dental care | en_HK |
dc.type | Article | en_HK |
dc.identifier.openurl | http://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1354-523X&volume=14&issue=2&spage=163&epage=173&date=2008&atitle=Sjögren’s+syndrome+sufferers+have+increased+oral+yeast+levels+despite+regular+dental+care | en_HK |
dc.identifier.email | Leung, KCM: kcmleung@hkucc.hku.hk | en_HK |
dc.identifier.email | McMillan, AS: annemcmillan@hku.hk | en_HK |
dc.identifier.email | Leung, WK: ewkleung@hkucc.hku.hk | en_HK |
dc.identifier.authority | Leung, KCM=rp00032 | en_HK |
dc.identifier.authority | McMillan, AS=rp00014 | en_HK |
dc.identifier.authority | Leung, WK=rp00019 | en_HK |
dc.description.nature | postprint | en_HK |
dc.identifier.doi | 10.1111/j.1601-0825.2007.01368.x | en_HK |
dc.identifier.pmid | 18302677 | - |
dc.identifier.scopus | eid_2-s2.0-39749125122 | en_HK |
dc.identifier.hkuros | 140750 | en_US |
dc.relation.references | http://www.scopus.com/mlt/select.url?eid=2-s2.0-39749125122&selection=ref&src=s&origin=recordpage | en_HK |
dc.identifier.volume | 14 | en_HK |
dc.identifier.issue | 2 | en_HK |
dc.identifier.spage | 163 | en_HK |
dc.identifier.epage | 173 | en_HK |
dc.identifier.eissn | 1601-0825 | - |
dc.identifier.isi | WOS:000253482000011 | - |
dc.publisher.place | United States | en_HK |
dc.identifier.scopusauthorid | Leung, KCM=26221830300 | en_HK |
dc.identifier.scopusauthorid | McMillan, AS=7102843317 | en_HK |
dc.identifier.scopusauthorid | Cheung, BPK=7103294773 | en_HK |
dc.identifier.scopusauthorid | Leung, WK=25224691800 | en_HK |
dc.identifier.citeulike | 2436620 | - |
dc.identifier.issnl | 1354-523X | - |