File Download
  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Microflora cultivable from minocycline strips placed in persisting periodontal pockets

TitleMicroflora cultivable from minocycline strips placed in persisting periodontal pockets
Authors
KeywordsAnaerobic bacteria
Local delivery
Minocycline
Periodontal diseases
Periodontal therapy
Issue Date2005
PublisherPergamon. The Journal's web site is located at http://www.elsevier.com/locate/archoralbio
Citation
Archives Of Oral Biology, 2005, v. 50 n. 1, p. 39-48 How to Cite?
AbstractThe microflora that develops on minocycline strips, used as an adjunct in non-surgical periodontal therapy was studied. Minocycline (1.4 mg in polycaprolactone vehicle) and control strips were applied into all residual pockets (PD ≥ 5 mm, ≥2 pockets/subject) of patients with chronic periodontitis 1 month after a course of non-surgical periodontal therapy. Strips were inserted and retained for 3 days, changed to new strips for 3 more days and then removed. Strips were recovered from 14 (eight test, six control) of the 34 participants at day 0 (strip inserted, left for 30 s, removed), days 3 and 6, for (i) anaerobic culture, (ii) coliforms culture, using MacConkey agar, (iii) yeast culture, using Sabouraud's dextrose agar. The mean anaerobic cfu/strip (×105; control/test) were 2/6, 24/2, 11/2 at days 0, 3 and 6, respectively (P > 0.05). The corresponding mean proportion of Gram-negative rods and fusiforms were 27%/21%, 27%/15% and 55%/8%. The proportions of Gram-negative rods on test strips by day 6 were significantly reduced (P < 0.05). A significantly increased prevalence of Streptococcus mitis biovar 1 was found on spent test strips (control versus test; 0% versus 38%, Fisher exact test, P = 0.01). Coliform prevalence at days 0, 3 and 6 on control/test strips were 0/13%, 50%/38% and 50%/13%. Yeasts were occasionally isolated. The findings indicated that the minocycline strips but not the control strip supported a microbial colonisation compatible with periodontal health by day 6. © 2004 Elsevier Ltd. All rights reserved.
Persistent Identifierhttp://hdl.handle.net/10722/55445
ISSN
2015 Impact Factor: 1.733
2015 SCImago Journal Rankings: 0.713
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorLeung, WKen_HK
dc.contributor.authorJin, Len_HK
dc.contributor.authorYau, JYYen_HK
dc.contributor.authorSun, Qen_HK
dc.contributor.authorCorbet, EFen_HK
dc.date.accessioned2009-08-06T03:37:42Z-
dc.date.available2009-08-06T03:37:42Z-
dc.date.issued2005en_HK
dc.identifier.citationArchives Of Oral Biology, 2005, v. 50 n. 1, p. 39-48en_HK
dc.identifier.issn0003-9969en_HK
dc.identifier.urihttp://hdl.handle.net/10722/55445-
dc.description.abstractThe microflora that develops on minocycline strips, used as an adjunct in non-surgical periodontal therapy was studied. Minocycline (1.4 mg in polycaprolactone vehicle) and control strips were applied into all residual pockets (PD ≥ 5 mm, ≥2 pockets/subject) of patients with chronic periodontitis 1 month after a course of non-surgical periodontal therapy. Strips were inserted and retained for 3 days, changed to new strips for 3 more days and then removed. Strips were recovered from 14 (eight test, six control) of the 34 participants at day 0 (strip inserted, left for 30 s, removed), days 3 and 6, for (i) anaerobic culture, (ii) coliforms culture, using MacConkey agar, (iii) yeast culture, using Sabouraud's dextrose agar. The mean anaerobic cfu/strip (×105; control/test) were 2/6, 24/2, 11/2 at days 0, 3 and 6, respectively (P > 0.05). The corresponding mean proportion of Gram-negative rods and fusiforms were 27%/21%, 27%/15% and 55%/8%. The proportions of Gram-negative rods on test strips by day 6 were significantly reduced (P < 0.05). A significantly increased prevalence of Streptococcus mitis biovar 1 was found on spent test strips (control versus test; 0% versus 38%, Fisher exact test, P = 0.01). Coliform prevalence at days 0, 3 and 6 on control/test strips were 0/13%, 50%/38% and 50%/13%. Yeasts were occasionally isolated. The findings indicated that the minocycline strips but not the control strip supported a microbial colonisation compatible with periodontal health by day 6. © 2004 Elsevier Ltd. All rights reserved.en_HK
dc.languageengen_HK
dc.publisherPergamon. The Journal's web site is located at http://www.elsevier.com/locate/archoralbioen_HK
dc.relation.ispartofArchives of Oral Biologyen_HK
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.subjectAnaerobic bacteriaen_HK
dc.subjectLocal deliveryen_HK
dc.subjectMinocyclineen_HK
dc.subjectPeriodontal diseasesen_HK
dc.subjectPeriodontal therapyen_HK
dc.subject.meshGram-Negative Facultatively Anaerobic Rods - isolation & purificationen_HK
dc.subject.meshPeriodontal Pocket - drug therapy - microbiologyen_HK
dc.subject.meshMinocycline - administration & dosageen_HK
dc.subject.meshAnti-Bacterial Agents - administration & dosageen_HK
dc.subject.meshStreptococcus mitis - isolation & purificationen_HK
dc.titleMicroflora cultivable from minocycline strips placed in persisting periodontal pocketsen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0003-9969&volume=50&issue=1&spage=39&epage=48&date=2005&atitle=Microflora+cultivable+from+minocycline+strips+placed+in+persisting+periodontal+pocketsen_HK
dc.identifier.emailLeung, WK:ewkleung@hkucc.hku.hken_HK
dc.identifier.emailJin, L:ljjin@hkucc.hku.hken_HK
dc.identifier.emailCorbet, EF:efcorbet@hku.hken_HK
dc.identifier.authorityLeung, WK=rp00019en_HK
dc.identifier.authorityJin, L=rp00028en_HK
dc.identifier.authorityCorbet, EF=rp00005en_HK
dc.description.naturepostprinten_HK
dc.identifier.doi10.1016/j.archoralbio.2004.08.002en_HK
dc.identifier.pmid15598416-
dc.identifier.scopuseid_2-s2.0-10344227224en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-10344227224&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume50en_HK
dc.identifier.issue1en_HK
dc.identifier.spage39en_HK
dc.identifier.epage48en_HK
dc.identifier.isiWOS:000226459500006-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridLeung, WK=25224691800en_HK
dc.identifier.scopusauthoridJin, L=7403328850en_HK
dc.identifier.scopusauthoridYau, JYY=7102167568en_HK
dc.identifier.scopusauthoridSun, Q=37041952700en_HK
dc.identifier.scopusauthoridCorbet, EF=35609873200en_HK

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats