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Article: An improved and general synthesis of monomers for incorporating trityl linker groups into polystyrene synthesis supports

TitleAn improved and general synthesis of monomers for incorporating trityl linker groups into polystyrene synthesis supports
Authors
KeywordsMonomers
Peptide synthesis
Trityl alcohols
Issue Date2004
PublisherPergamon. The Journal's web site is located at http://www.elsevier.com/locate/tet
Citation
Tetrahedron, 2004, v. 60 n. 12, p. 2903-2907 How to Cite?
AbstractA straightforward synthesis of trityl alcohols in which one of the aryl rings is substituted with a vinyl group is presented. The synthesis of the alcohols involves the direct addition of the Grignard reagent prepared from 4-bromostyrene to substituted benzophenones. These compounds are used to incorporate trityl linker groups into polystyrene-based organic synthesis supports. Both non-cross-linked and cross-linked (JandaJel™) polystyrene have been prepared using these monomers. © 2004 Elsevier Ltd. All rights reserved.
Persistent Identifierhttp://hdl.handle.net/10722/54259
ISSN
2015 Impact Factor: 2.645
2015 SCImago Journal Rankings: 0.991
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorChoi, MKWen_HK
dc.contributor.authorToy, PHen_HK
dc.date.accessioned2009-04-03T07:41:22Z-
dc.date.available2009-04-03T07:41:22Z-
dc.date.issued2004en_HK
dc.identifier.citationTetrahedron, 2004, v. 60 n. 12, p. 2903-2907en_HK
dc.identifier.issn0040-4020en_HK
dc.identifier.urihttp://hdl.handle.net/10722/54259-
dc.description.abstractA straightforward synthesis of trityl alcohols in which one of the aryl rings is substituted with a vinyl group is presented. The synthesis of the alcohols involves the direct addition of the Grignard reagent prepared from 4-bromostyrene to substituted benzophenones. These compounds are used to incorporate trityl linker groups into polystyrene-based organic synthesis supports. Both non-cross-linked and cross-linked (JandaJel™) polystyrene have been prepared using these monomers. © 2004 Elsevier Ltd. All rights reserved.en_HK
dc.languageengen_HK
dc.publisherPergamon. The Journal's web site is located at http://www.elsevier.com/locate/teten_HK
dc.relation.ispartofTetrahedronen_HK
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.subjectMonomersen_HK
dc.subjectPeptide synthesisen_HK
dc.subjectTrityl alcoholsen_HK
dc.titleAn improved and general synthesis of monomers for incorporating trityl linker groups into polystyrene synthesis supportsen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0040-4020&volume=60&issue=12&spage=2903&epage=2907&date=2004&atitle=An+improved+and+general+synthesis+of+monomers+for+incorporating+trityl+linker+groups+into+polystyrene+synthesis+supportsen_HK
dc.identifier.emailToy, PH:phtoy@hkucc.hku.hken_HK
dc.identifier.authorityToy, PH=rp00791en_HK
dc.description.naturepostprinten_HK
dc.identifier.doi10.1016/j.tet.2004.01.027en_HK
dc.identifier.scopuseid_2-s2.0-1542375254en_HK
dc.identifier.hkuros90434-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-1542375254&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume60en_HK
dc.identifier.issue12en_HK
dc.identifier.spage2903en_HK
dc.identifier.epage2907en_HK
dc.identifier.isiWOS:000220257900022-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridChoi, MKW=7402093591en_HK
dc.identifier.scopusauthoridToy, PH=7006579247en_HK

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