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Conference Paper: A comparison of dexmedetomidine and midazolam for sedation in third molar surgery

TitleA comparison of dexmedetomidine and midazolam for sedation in third molar surgery
Authors
Issue Date2007
PublisherChurchill Livingstone. The Journal's web site is located at http://www.wiley.com/bw/journal.asp?ref=0003-2409
Citation
The 11th International Dental Congress on Modern Pain Control, Yokohama, Japan, 4–7 October 2006. In Anaesthesia (Oxford), 2007, v. 62 n. 11, p. 1132-1138 How to Cite?
AbstractThis randomised, double-blind study compared dexmedetomidine and midazolam for intravenous sedation during third molar surgery under local anaesthesia. Sixty patients received either dexmedetomidine (up to 1 microg x kg(-1)) or midazolam (up to 5 mg), which was infused until the Ramsay Sedation Score was four or the maximum dose limit was reached. Intra-operative vital signs, postoperative pain scores and analgesic consumption, amnesia, and satisfaction scores for patients and surgeons, were recorded. Sedation was achieved by median (IQR (range)) doses of 47 microg (39-52 (25-76)) or 0.88 microg x kg(-1) (0.75-1.0 (0.6-1.0)) dexmedetomidine, and 3.6 mg (3.3-4.4 (1.9-5.0)) or 0.07 mg x kg(-1) (0.055-0.085 (0.017-0.12)) midazolam. Heart rate and blood pressure during surgery were lower in dexmedetomidine group. There was no significant difference in satisfaction or pain scores. Midazolam was associated with greater amnesia. Dexmedetomidine produces comparable sedation to midazolam.
Persistent Identifierhttp://hdl.handle.net/10722/54234
ISSN
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorCheung, CWen_HK
dc.contributor.authorYing, CLAen_HK
dc.contributor.authorChiu, WKen_HK
dc.contributor.authorWong, GTCen_HK
dc.contributor.authorNg, KFJen_HK
dc.contributor.authorIrwin, MGen_HK
dc.date.accessioned2009-04-03T07:40:35Z-
dc.date.available2009-04-03T07:40:35Z-
dc.date.issued2007en_HK
dc.identifier.citationThe 11th International Dental Congress on Modern Pain Control, Yokohama, Japan, 4–7 October 2006. In Anaesthesia (Oxford), 2007, v. 62 n. 11, p. 1132-1138en_HK
dc.identifier.issn0263-1512en_HK
dc.identifier.urihttp://hdl.handle.net/10722/54234-
dc.description.abstractThis randomised, double-blind study compared dexmedetomidine and midazolam for intravenous sedation during third molar surgery under local anaesthesia. Sixty patients received either dexmedetomidine (up to 1 microg x kg(-1)) or midazolam (up to 5 mg), which was infused until the Ramsay Sedation Score was four or the maximum dose limit was reached. Intra-operative vital signs, postoperative pain scores and analgesic consumption, amnesia, and satisfaction scores for patients and surgeons, were recorded. Sedation was achieved by median (IQR (range)) doses of 47 microg (39-52 (25-76)) or 0.88 microg x kg(-1) (0.75-1.0 (0.6-1.0)) dexmedetomidine, and 3.6 mg (3.3-4.4 (1.9-5.0)) or 0.07 mg x kg(-1) (0.055-0.085 (0.017-0.12)) midazolam. Heart rate and blood pressure during surgery were lower in dexmedetomidine group. There was no significant difference in satisfaction or pain scores. Midazolam was associated with greater amnesia. Dexmedetomidine produces comparable sedation to midazolam.en_HK
dc.languageengen_HK
dc.publisherChurchill Livingstone. The Journal's web site is located at http://www.wiley.com/bw/journal.asp?ref=0003-2409en_HK
dc.relation.ispartofAnaesthesia (Oxford)en_HK
dc.subject.meshConscious Sedation - methodsen_HK
dc.subject.meshDexmedetomidineen_HK
dc.subject.meshHypnotics and Sedativesen_HK
dc.subject.meshMidazolamen_HK
dc.subject.meshMolar, Third - surgeryen_HK
dc.titleA comparison of dexmedetomidine and midazolam for sedation in third molar surgeryen_HK
dc.typeConference_Paperen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0263-1512&volume=62&issue=11&spage=1132&epage=1138&date=2007&atitle=A+comparison+of+dexmedetomidine+and+midazolam+for+sedation+in+third+molar+surgeryen_HK
dc.identifier.emailCheung, CW: cheucw@hku.hken_HK
dc.identifier.emailChiu, WK: chiuken@hku.hken_HK
dc.identifier.emailWong, GTC: gordon@hku.hken_HK
dc.identifier.emailNg, KFJ: jkfng@hku.hken_HK
dc.identifier.emailIrwin, MG: mgirwin@hkucc.hku.hk-
dc.identifier.authorityCheung, CW=rp00244en_HK
dc.identifier.authorityWong, GTC=rp00523en_HK
dc.identifier.authorityNg, KFJ=rp00544en_HK
dc.identifier.authorityIrwin, MG=rp00390en_HK
dc.description.naturepostprinten_HK
dc.identifier.doi10.1111/j.1365-2044.2007.05230.xen_HK
dc.identifier.pmid17924894-
dc.identifier.scopuseid_2-s2.0-35048825290en_HK
dc.identifier.hkuros152258-
dc.identifier.hkuros215336-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-35048825290&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume62en_HK
dc.identifier.issue11en_HK
dc.identifier.spage1132en_HK
dc.identifier.epage1138en_HK
dc.identifier.isiWOS:000250012500009-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.citeulike1794238-
dc.customcontrol.immutablesml 160614 amended-

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