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Article: Kawasaki disease in Hong Kong, 1994 to 2000
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TitleKawasaki disease in Hong Kong, 1994 to 2000
1994年至2000年香港的川崎氏病
 
AuthorsNg, YM5
Sung, RYT6
So, LY7
Fong, NC3
Ho, MHK9
Cheng, YW4
Lee, SH5
Mak, WC2
Wong, DML5
Yam, MC6
Kwok, KL1
Chiu, WK8
 
Issue Date2005
 
PublisherHong Kong Medical Association. The Journal's web site is located at http://www.hkmj.org
 
CitationHong Kong Medical Journal, 2005, v. 11 n. 5, p. 331-335 [How to Cite?]
 
AbstractOBJECTIVE. To describe the epidemiology, clinical characteristics, and management of Kawasaki disease in children in Hong Kong. DESIGN. Retrospective survey of medical records from July 1994 to June 1997, and prospective data collection from July 1997 to June 2000. SETTING. Hospitals with a paediatric unit in Hong Kong. PATIENTS. Patients diagnosed with Kawasaki disease between July 1994 and June 2000 in public hospitals in Hong Kong. MAIN OUTCOME MEASURES. Incidence of Kawasaki disease and coronary artery aneurysm rates. RESULTS. A total of 696 cases of Kawasaki disease were reported. There were 435 (62.5%) boys and 261 (37.5%) girls giving a male to female ratio of 1.7:1. The age ranged from 1 month to 15 years 5 months with a median of 1.7 years. Infants (<1 year) constituted the largest group of patients (223,32.0%) and overall, 638 (91.7%) were younger than 5 years. Skin rash, conjunctivitis, and oral signs were among the principal clinical features present in over 80% of cases. Prominent cervical lymph nodes larger than 1.5 cm were less commonly found (24%). Coronary artery aneurysms or ectasia were present in 15.7% (109/696), 8.5% (59/696), and 5.0% (35/696) of patients at 2, 4, and 8 weeks, respectively. The incidence of Kawasaki disease per 100 000 children under 5 years was significantly higher in the prospective study period than in the retrospective period (39 vs 26, <0.001). CONCLUSION. The incidence of Kawasaki disease is high in Hong Kong and is 39 per 100 000 children below 5 years of age. The coronary artery aneurysm prevalence is 5%. Intravenous gamma-globulin and high-dose aspirin is the mainstay of treatment.
 
ISSN1024-2708
2013 SCImago Journal Rankings: 0.293
 
DC FieldValue
dc.contributor.authorNg, YM
 
dc.contributor.authorSung, RYT
 
dc.contributor.authorSo, LY
 
dc.contributor.authorFong, NC
 
dc.contributor.authorHo, MHK
 
dc.contributor.authorCheng, YW
 
dc.contributor.authorLee, SH
 
dc.contributor.authorMak, WC
 
dc.contributor.authorWong, DML
 
dc.contributor.authorYam, MC
 
dc.contributor.authorKwok, KL
 
dc.contributor.authorChiu, WK
 
dc.date.accessioned2009-04-03T07:20:10Z
 
dc.date.available2009-04-03T07:20:10Z
 
dc.date.issued2005
 
dc.description.abstractOBJECTIVE. To describe the epidemiology, clinical characteristics, and management of Kawasaki disease in children in Hong Kong. DESIGN. Retrospective survey of medical records from July 1994 to June 1997, and prospective data collection from July 1997 to June 2000. SETTING. Hospitals with a paediatric unit in Hong Kong. PATIENTS. Patients diagnosed with Kawasaki disease between July 1994 and June 2000 in public hospitals in Hong Kong. MAIN OUTCOME MEASURES. Incidence of Kawasaki disease and coronary artery aneurysm rates. RESULTS. A total of 696 cases of Kawasaki disease were reported. There were 435 (62.5%) boys and 261 (37.5%) girls giving a male to female ratio of 1.7:1. The age ranged from 1 month to 15 years 5 months with a median of 1.7 years. Infants (<1 year) constituted the largest group of patients (223,32.0%) and overall, 638 (91.7%) were younger than 5 years. Skin rash, conjunctivitis, and oral signs were among the principal clinical features present in over 80% of cases. Prominent cervical lymph nodes larger than 1.5 cm were less commonly found (24%). Coronary artery aneurysms or ectasia were present in 15.7% (109/696), 8.5% (59/696), and 5.0% (35/696) of patients at 2, 4, and 8 weeks, respectively. The incidence of Kawasaki disease per 100 000 children under 5 years was significantly higher in the prospective study period than in the retrospective period (39 vs 26, <0.001). CONCLUSION. The incidence of Kawasaki disease is high in Hong Kong and is 39 per 100 000 children below 5 years of age. The coronary artery aneurysm prevalence is 5%. Intravenous gamma-globulin and high-dose aspirin is the mainstay of treatment.
 
dc.description.naturepublished_or_final_version
 
dc.identifier.citationHong Kong Medical Journal, 2005, v. 11 n. 5, p. 331-335 [How to Cite?]
 
dc.identifier.hkuros111521
 
dc.identifier.issn1024-2708
2013 SCImago Journal Rankings: 0.293
 
dc.identifier.openurl
 
dc.identifier.pmid16219951
 
dc.identifier.scopuseid_2-s2.0-27144556638
 
dc.identifier.urihttp://hdl.handle.net/10722/53452
 
dc.languageeng
 
dc.publisherHong Kong Medical Association. The Journal's web site is located at http://www.hkmj.org
 
dc.rightsHong Kong Medical Journal. Copyright © Hong Kong Medical Association.
 
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License
 
dc.subject.meshMucocutaneous Lymph Node Syndrome - epidemiology
 
dc.subject.meshChi-Square Distribution
 
dc.subject.meshChild, Preschool
 
dc.subject.meshHong Kong - epidemiology
 
dc.subject.meshRetrospective Studies
 
dc.titleKawasaki disease in Hong Kong, 1994 to 2000
 
dc.title1994年至2000年香港的川崎氏病
 
dc.typeArticle
 
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<item><contributor.author>Ng, YM</contributor.author>
<contributor.author>Sung, RYT</contributor.author>
<contributor.author>So, LY</contributor.author>
<contributor.author>Fong, NC</contributor.author>
<contributor.author>Ho, MHK</contributor.author>
<contributor.author>Cheng, YW</contributor.author>
<contributor.author>Lee, SH</contributor.author>
<contributor.author>Mak, WC</contributor.author>
<contributor.author>Wong, DML</contributor.author>
<contributor.author>Yam, MC</contributor.author>
<contributor.author>Kwok, KL</contributor.author>
<contributor.author>Chiu, WK</contributor.author>
<date.accessioned>2009-04-03T07:20:10Z</date.accessioned>
<date.available>2009-04-03T07:20:10Z</date.available>
<date.issued>2005</date.issued>
<identifier.citation>Hong Kong Medical Journal, 2005, v. 11 n. 5, p. 331-335</identifier.citation>
<identifier.issn>1024-2708</identifier.issn>
<identifier.uri>http://hdl.handle.net/10722/53452</identifier.uri>
<description.abstract>OBJECTIVE. To describe the epidemiology, clinical characteristics, and management of Kawasaki disease in children in Hong Kong.
DESIGN. Retrospective survey of medical records from July 1994 to June 1997, and prospective data collection from July 1997 to June 2000.
SETTING. Hospitals with a paediatric unit in Hong Kong.
PATIENTS. Patients diagnosed with Kawasaki disease between July 1994 and June 2000 in public hospitals in Hong Kong.
MAIN OUTCOME MEASURES. Incidence of Kawasaki disease and coronary artery aneurysm rates.
RESULTS. A total of 696 cases of Kawasaki disease were reported. There were 435 (62.5%) boys and 261 (37.5%) girls giving a male to female ratio of 1.7:1. The age ranged from 1 month to 15 years 5 months with a median of 1.7 years. Infants (&lt;1 year) constituted the largest group of patients (223,32.0%) and overall, 638 (91.7%) were younger than 5 years. Skin rash, conjunctivitis, and oral signs were among the principal clinical features present in over 80% of cases. Prominent cervical lymph nodes larger than 1.5 cm were less commonly found (24%). Coronary artery aneurysms or ectasia were present in 15.7% (109/696), 8.5% (59/696), and 5.0% (35/696) of patients at 2, 4, and 8 weeks, respectively. The incidence of Kawasaki disease per 100 000 children under 5 years was significantly higher in the prospective study period than in the retrospective period (39 vs 26, &lt;0.001).
CONCLUSION. The incidence of Kawasaki disease is high in Hong Kong and is 39 per
100 000 children below 5 years of age. The coronary artery aneurysm prevalence is 5%. Intravenous gamma-globulin and high-dose aspirin is the mainstay of treatment.</description.abstract>
<language>eng</language>
<publisher>Hong Kong Medical Association. The Journal&apos;s web site is located at http://www.hkmj.org</publisher>
<rights>Hong Kong Medical Journal. Copyright &#169; Hong Kong Medical Association.</rights>
<rights>Creative Commons: Attribution 3.0 Hong Kong License</rights>
<subject.mesh>Mucocutaneous Lymph Node Syndrome - epidemiology</subject.mesh>
<subject.mesh>Chi-Square Distribution</subject.mesh>
<subject.mesh>Child, Preschool</subject.mesh>
<subject.mesh>Hong Kong - epidemiology</subject.mesh>
<subject.mesh>Retrospective Studies</subject.mesh>
<title>Kawasaki disease in Hong Kong, 1994 to 2000</title>
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Author Affiliations
  1. Kwong Wah Hospital
  2. Tseung Kwan O Hospital
  3. Princess Margaret Hospital Hong Kong
  4. Tuen Mun Hospital
  5. Queen Elizabeth Hospital Hong Kong
  6. Prince of Wales Hospital Hong Kong
  7. Pamela Youde Nethersole Eastern Hospital
  8. United Christian Hospital Hong Kong
  9. Queen Mary Hospital Hong Kong