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Article: Kawasaki disease in Hong Kong, 1994 to 2000

TitleKawasaki disease in Hong Kong, 1994 to 2000
1994年至2000年香港的川崎氏病
Authors
Issue Date2005
PublisherHong Kong Medical Association. The Journal's web site is located at http://www.hkmj.org
Citation
Hong Kong Medical Journal, 2005, v. 11 n. 5, p. 331-335 How to Cite?
AbstractOBJECTIVE. To describe the epidemiology, clinical characteristics, and management of Kawasaki disease in children in Hong Kong. DESIGN. Retrospective survey of medical records from July 1994 to June 1997, and prospective data collection from July 1997 to June 2000. SETTING. Hospitals with a paediatric unit in Hong Kong. PATIENTS. Patients diagnosed with Kawasaki disease between July 1994 and June 2000 in public hospitals in Hong Kong. MAIN OUTCOME MEASURES. Incidence of Kawasaki disease and coronary artery aneurysm rates. RESULTS. A total of 696 cases of Kawasaki disease were reported. There were 435 (62.5%) boys and 261 (37.5%) girls giving a male to female ratio of 1.7:1. The age ranged from 1 month to 15 years 5 months with a median of 1.7 years. Infants (<1 year) constituted the largest group of patients (223,32.0%) and overall, 638 (91.7%) were younger than 5 years. Skin rash, conjunctivitis, and oral signs were among the principal clinical features present in over 80% of cases. Prominent cervical lymph nodes larger than 1.5 cm were less commonly found (24%). Coronary artery aneurysms or ectasia were present in 15.7% (109/696), 8.5% (59/696), and 5.0% (35/696) of patients at 2, 4, and 8 weeks, respectively. The incidence of Kawasaki disease per 100 000 children under 5 years was significantly higher in the prospective study period than in the retrospective period (39 vs 26, <0.001). CONCLUSION. The incidence of Kawasaki disease is high in Hong Kong and is 39 per 100 000 children below 5 years of age. The coronary artery aneurysm prevalence is 5%. Intravenous gamma-globulin and high-dose aspirin is the mainstay of treatment.
Persistent Identifierhttp://hdl.handle.net/10722/53452
ISSN
2015 Impact Factor: 0.887
2015 SCImago Journal Rankings: 0.279

 

DC FieldValueLanguage
dc.contributor.authorNg, YMen_HK
dc.contributor.authorSung, RYTen_HK
dc.contributor.authorSo, LYen_HK
dc.contributor.authorFong, NCen_HK
dc.contributor.authorHo, MHKen_HK
dc.contributor.authorCheng, YWen_HK
dc.contributor.authorLee, SHen_HK
dc.contributor.authorMak, WCen_HK
dc.contributor.authorWong, DMLen_HK
dc.contributor.authorYam, MCen_HK
dc.contributor.authorKwok, KLen_HK
dc.contributor.authorChiu, WKen_HK
dc.date.accessioned2009-04-03T07:20:10Z-
dc.date.available2009-04-03T07:20:10Z-
dc.date.issued2005en_HK
dc.identifier.citationHong Kong Medical Journal, 2005, v. 11 n. 5, p. 331-335en_HK
dc.identifier.issn1024-2708en_HK
dc.identifier.urihttp://hdl.handle.net/10722/53452-
dc.description.abstractOBJECTIVE. To describe the epidemiology, clinical characteristics, and management of Kawasaki disease in children in Hong Kong. DESIGN. Retrospective survey of medical records from July 1994 to June 1997, and prospective data collection from July 1997 to June 2000. SETTING. Hospitals with a paediatric unit in Hong Kong. PATIENTS. Patients diagnosed with Kawasaki disease between July 1994 and June 2000 in public hospitals in Hong Kong. MAIN OUTCOME MEASURES. Incidence of Kawasaki disease and coronary artery aneurysm rates. RESULTS. A total of 696 cases of Kawasaki disease were reported. There were 435 (62.5%) boys and 261 (37.5%) girls giving a male to female ratio of 1.7:1. The age ranged from 1 month to 15 years 5 months with a median of 1.7 years. Infants (<1 year) constituted the largest group of patients (223,32.0%) and overall, 638 (91.7%) were younger than 5 years. Skin rash, conjunctivitis, and oral signs were among the principal clinical features present in over 80% of cases. Prominent cervical lymph nodes larger than 1.5 cm were less commonly found (24%). Coronary artery aneurysms or ectasia were present in 15.7% (109/696), 8.5% (59/696), and 5.0% (35/696) of patients at 2, 4, and 8 weeks, respectively. The incidence of Kawasaki disease per 100 000 children under 5 years was significantly higher in the prospective study period than in the retrospective period (39 vs 26, <0.001). CONCLUSION. The incidence of Kawasaki disease is high in Hong Kong and is 39 per 100 000 children below 5 years of age. The coronary artery aneurysm prevalence is 5%. Intravenous gamma-globulin and high-dose aspirin is the mainstay of treatment.en_HK
dc.languageengen_HK
dc.publisherHong Kong Medical Association. The Journal's web site is located at http://www.hkmj.orgen_HK
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.rightsHong Kong Medical Journal. Copyright © Hong Kong Medical Association.en_HK
dc.subject.meshMucocutaneous Lymph Node Syndrome - epidemiologyen_HK
dc.subject.meshChi-Square Distributionen_HK
dc.subject.meshChild, Preschoolen_HK
dc.subject.meshHong Kong - epidemiologyen_HK
dc.subject.meshRetrospective Studiesen_HK
dc.titleKawasaki disease in Hong Kong, 1994 to 2000en_HK
dc.title1994年至2000年香港的川崎氏病zh_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1024-2708&volume=11&issue=5&spage=331&epage=335&date=2005&atitle=Kawasaki+disease+in+Hong+Kong,+1994+to+2000en_HK
dc.identifier.emailNg, YM: ngyin@HKUCC.hku.hken_HK
dc.identifier.emailHo, MHK: marcoho@HKUCC.hku.hken_HK
dc.description.naturepublished_or_final_versionen_HK
dc.identifier.pmid16219951-
dc.identifier.scopuseid_2-s2.0-27144556638-
dc.identifier.hkuros111521-

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