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Article: Chondromyxoid fibroma of skull base: A tumour prone to local recurrence

TitleChondromyxoid fibroma of skull base: A tumour prone to local recurrence
Authors
KeywordsChondromyxoid fibroma
Electron microscopy
Nasal cavity
Skull base
Issue Date1999
PublisherCambridge University Press. The Journal's web site is located at http://journals.cambridge.org/action/displayJournal?jid=JLO
Citation
Journal Of Laryngology And Otology, 1999, v. 113 n. 4, p. 380-385 How to Cite?
AbstractChondromyxoid fibroma of the skull base is extremely uncommon. Sometimes involvement of the nasal cavity may occur and the patients may present with nasal symptoms. The biological behaviour of this tumour has not been well studied, primarily because of the limited number of reported cases and the short duration of follow-up. We report a histologically confirmed case of chondromyxoid fibroma of the skull base that recurred repeatedly over a 10-year period after the initial operation. Histologically it showed identical morphology to the original tumour with no evidence of histological progression or dedifferentiation. Ultrastructurally, the spindle tumour cells in the fibromyxoid area showed dual chondroblastic and fibroblastic differentiation, suggesting that these spindle fibroblastic cells and the better differentiated chondroid cells were of the same cell type with different histological morphology.
Persistent Identifierhttp://hdl.handle.net/10722/53332
ISSN
2015 Impact Factor: 0.736
2015 SCImago Journal Rankings: 0.447
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorShek, TWHen_HK
dc.contributor.authorPeh, WCGen_HK
dc.contributor.authorLeung, Gen_HK
dc.date.accessioned2009-04-03T07:16:58Z-
dc.date.available2009-04-03T07:16:58Z-
dc.date.issued1999en_HK
dc.identifier.citationJournal Of Laryngology And Otology, 1999, v. 113 n. 4, p. 380-385en_HK
dc.identifier.issn0022-2151en_HK
dc.identifier.urihttp://hdl.handle.net/10722/53332-
dc.description.abstractChondromyxoid fibroma of the skull base is extremely uncommon. Sometimes involvement of the nasal cavity may occur and the patients may present with nasal symptoms. The biological behaviour of this tumour has not been well studied, primarily because of the limited number of reported cases and the short duration of follow-up. We report a histologically confirmed case of chondromyxoid fibroma of the skull base that recurred repeatedly over a 10-year period after the initial operation. Histologically it showed identical morphology to the original tumour with no evidence of histological progression or dedifferentiation. Ultrastructurally, the spindle tumour cells in the fibromyxoid area showed dual chondroblastic and fibroblastic differentiation, suggesting that these spindle fibroblastic cells and the better differentiated chondroid cells were of the same cell type with different histological morphology.en_HK
dc.languageengen_HK
dc.publisherCambridge University Press. The Journal's web site is located at http://journals.cambridge.org/action/displayJournal?jid=JLOen_HK
dc.relation.ispartofJournal of Laryngology and Otologyen_HK
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.rightsJournal of Laryngology and Otology. Copyright © Cambridge University Press.en_HK
dc.subjectChondromyxoid fibromaen_HK
dc.subjectElectron microscopyen_HK
dc.subjectNasal cavityen_HK
dc.subjectSkull baseen_HK
dc.subject.meshChondroblastoma - diagnosis - pathology - surgeryen_HK
dc.subject.meshSkull Neoplasms - diagnosis - pathology - surgeryen_HK
dc.subject.meshNeoplasm Recurrence, Local - pathology - surgeryen_HK
dc.subject.meshMicroscopy, Electronen_HK
dc.subject.meshTomography, X-Ray Computeden_HK
dc.titleChondromyxoid fibroma of skull base: A tumour prone to local recurrenceen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0022-2151&volume=113&issue=4&spage=380&epage=385&date=1999&atitle=Chondromyxoid+fibroma+of+skull+base:+a+tumour+prone+to+local+recurrenceen_HK
dc.identifier.emailLeung, G: gilberto@hkucc.hku.hken_HK
dc.identifier.authorityLeung, G=rp00522en_HK
dc.description.naturepublished_or_final_versionen_HK
dc.identifier.pmid10474681-
dc.identifier.scopuseid_2-s2.0-0032904285en_HK
dc.identifier.hkuros42709-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0032904285&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume113en_HK
dc.identifier.issue4en_HK
dc.identifier.spage380en_HK
dc.identifier.epage385en_HK
dc.identifier.isiWOS:000079998200021-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridShek, TWH=7005479861en_HK
dc.identifier.scopusauthoridPeh, WCG=7101824984en_HK
dc.identifier.scopusauthoridLeung, G=35965118200en_HK

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