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Article: A two-year randomized clinical trial of chlorhexidine varnish on dental caries in Chinese preschool children

TitleA two-year randomized clinical trial of chlorhexidine varnish on dental caries in Chinese preschool children
Authors
KeywordsClinical trial
Chlorhexidine varnish
Caries prevention
Primary teeth
Issue Date2006
PublisherSage Publications, Inc.. The Journal's web site is located at http://www.sagepub.com/journalsProdDesc.nav?prodId=Journal201925
Citation
Journal Of Dental Research, 2006, v. 85 n. 6, p. 557-559 How to Cite?
AbstractThe objective of this study was to assess the effect of six-monthly professional applications of chlorhexidine varnish on the prevention of dental caries in primary molars in Chinese preschool children. In a double-blinded, randomized, placebo-controlled clinical trial, 334 children aged 4-5 years were randomly divided into two groups. Children in the test group received six-monthly applications of a 40% chlorhexidine varnish, and the control children received a placebo varnish. Caries status of the children was assessed by two calibrated examiners at baseline and after 24 months, according to criteria recommended by the World Health Organization. The two-year mean caries increments in the test and the control group children were 1.0 and 1.6 decayed, missing, or filled molar surfaces (dmfs-molar), respectively, a 37.3% reduction (t test, p = 0.036). No side-effects were found. It was concluded that six-monthly applications of chlorhexidine varnish were effective in reducing the incidence of dental caries in primary molars.
Persistent Identifierhttp://hdl.handle.net/10722/53308
ISSN
2015 Impact Factor: 4.602
2015 SCImago Journal Rankings: 1.714
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorDu, MQen_HK
dc.contributor.authorTai, BJen_HK
dc.contributor.authorJiang, Hen_HK
dc.contributor.authorLo, ECMen_HK
dc.contributor.authorFan, MWen_HK
dc.contributor.authorBian, Zen_HK
dc.date.accessioned2009-04-03T07:06:28Z-
dc.date.available2009-04-03T07:06:28Z-
dc.date.issued2006en_HK
dc.identifier.citationJournal Of Dental Research, 2006, v. 85 n. 6, p. 557-559en_HK
dc.identifier.issn0022-0345en_HK
dc.identifier.urihttp://hdl.handle.net/10722/53308-
dc.description.abstractThe objective of this study was to assess the effect of six-monthly professional applications of chlorhexidine varnish on the prevention of dental caries in primary molars in Chinese preschool children. In a double-blinded, randomized, placebo-controlled clinical trial, 334 children aged 4-5 years were randomly divided into two groups. Children in the test group received six-monthly applications of a 40% chlorhexidine varnish, and the control children received a placebo varnish. Caries status of the children was assessed by two calibrated examiners at baseline and after 24 months, according to criteria recommended by the World Health Organization. The two-year mean caries increments in the test and the control group children were 1.0 and 1.6 decayed, missing, or filled molar surfaces (dmfs-molar), respectively, a 37.3% reduction (t test, p = 0.036). No side-effects were found. It was concluded that six-monthly applications of chlorhexidine varnish were effective in reducing the incidence of dental caries in primary molars.en_HK
dc.languageengen_HK
dc.publisherSage Publications, Inc.. The Journal's web site is located at http://www.sagepub.com/journalsProdDesc.nav?prodId=Journal201925en_HK
dc.relation.ispartofJournal of Dental Researchen_HK
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.subjectClinical trialen_HK
dc.subjectChlorhexidine varnishen_HK
dc.subjectCaries preventionen_HK
dc.subjectPrimary teethen_HK
dc.subject.meshAdministration, Topicalen_HK
dc.subject.meshChild, Preschoolen_HK
dc.subject.meshChinaen_HK
dc.subject.meshChlorhexidine - administration & dosage - therapeutic useen_HK
dc.subject.meshDMF Indexen_HK
dc.subject.meshDental Caries - prevention & controlen_HK
dc.subject.meshDouble-Blind Methoden_HK
dc.subject.meshFollow-Up Studiesen_HK
dc.subject.meshHumansen_HK
dc.subject.meshMolar - drug effectsen_HK
dc.subject.meshPlacebosen_HK
dc.titleA two-year randomized clinical trial of chlorhexidine varnish on dental caries in Chinese preschool childrenen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0022-0345&volume=85&issue=6&spage=557&epage=559&date=2006&atitle=A+two-year+randomized+clinical+trial+of+chlorhexidine+varnish+on+dental+caries+in+Chinese+preschool+childrenen_HK
dc.identifier.emailLo, ECM:hrdplcm@hkucc.hku.hken_HK
dc.identifier.authorityLo, ECM=rp00015en_HK
dc.description.naturepublished_or_final_versionen_HK
dc.identifier.pmid16723655-
dc.identifier.scopuseid_2-s2.0-33745369331en_HK
dc.identifier.hkuros116684-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-33745369331&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume85en_HK
dc.identifier.issue6en_HK
dc.identifier.spage557en_HK
dc.identifier.epage559en_HK
dc.identifier.isiWOS:000239775300015-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridDu, MQ=7201997846en_HK
dc.identifier.scopusauthoridTai, BJ=7004532036en_HK
dc.identifier.scopusauthoridJiang, H=14028307900en_HK
dc.identifier.scopusauthoridLo, ECM=7101705982en_HK
dc.identifier.scopusauthoridFan, MW=7201970773en_HK
dc.identifier.scopusauthoridBian, Z=7103314705en_HK

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