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Article: Clinical predictors of non-diabetic renal disease in patients with non-insulin dependent diabetes mellitus

TitleClinical predictors of non-diabetic renal disease in patients with non-insulin dependent diabetes mellitus
Authors
KeywordsMicroscopic haematuria
Non-diabetic renal disease
Non-insulin dependent diabetes mellitus
Non-nephrotic proteinuria
Issue Date1997
PublisherOxford University Press. The Journal's web site is located at http://ndt.oxfordjournals.org/
Citation
Nephrology Dialysis Transplantation, 1997, v. 12 n. 12, p. 2588-2591 How to Cite?
AbstractBackground. Several studies had suggested that non-diabetic renal disease (NDRD) was common among non-insulin dependent diabetes mellitus (NIDDM) patients with renal involvement. Methods. We prospectively studied the prevalence of NDRD among a Chinese NIDDM population. Renal biopsy specimens were evaluated with light-, immunohistological and electron-microscopy. The cohort consisted of 51 patients who had NIDDM and proteinuria > 1 g/24 h. Results. Patients with both isolated diabetic nephropathy (DN, n = 34) and NDRD (n = 17) had comparable duration of DM, creatinine clearance, serum creatinine, albumin and glycosylated haemoglobin levels, as well as incidences of retinopathy, neuropathy and hypertension. Significantly more patients with NDRD had microscopic haematuria (P = 0.043) or non-nephrotic proteinuria (P = 0.004). IgA nephropathy accounted for 59% of the NDRD identified. Conclusions. In this study, microscopic haematuria and non-nephrotic proteinuria predicted the presence of NDRD among NIDDM patients presenting with renal disease.
Persistent Identifierhttp://hdl.handle.net/10722/49411
ISSN
2015 Impact Factor: 4.085
2015 SCImago Journal Rankings: 1.780
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorMak, SKen_HK
dc.contributor.authorGwi, Een_HK
dc.contributor.authorChan, KWen_HK
dc.contributor.authorWong, PNen_HK
dc.contributor.authorLo, KYen_HK
dc.contributor.authorLee, KFen_HK
dc.contributor.authorWong, AKMen_HK
dc.date.accessioned2008-06-12T06:41:54Z-
dc.date.available2008-06-12T06:41:54Z-
dc.date.issued1997en_HK
dc.identifier.citationNephrology Dialysis Transplantation, 1997, v. 12 n. 12, p. 2588-2591en_HK
dc.identifier.issn0931-0509en_HK
dc.identifier.urihttp://hdl.handle.net/10722/49411-
dc.description.abstractBackground. Several studies had suggested that non-diabetic renal disease (NDRD) was common among non-insulin dependent diabetes mellitus (NIDDM) patients with renal involvement. Methods. We prospectively studied the prevalence of NDRD among a Chinese NIDDM population. Renal biopsy specimens were evaluated with light-, immunohistological and electron-microscopy. The cohort consisted of 51 patients who had NIDDM and proteinuria > 1 g/24 h. Results. Patients with both isolated diabetic nephropathy (DN, n = 34) and NDRD (n = 17) had comparable duration of DM, creatinine clearance, serum creatinine, albumin and glycosylated haemoglobin levels, as well as incidences of retinopathy, neuropathy and hypertension. Significantly more patients with NDRD had microscopic haematuria (P = 0.043) or non-nephrotic proteinuria (P = 0.004). IgA nephropathy accounted for 59% of the NDRD identified. Conclusions. In this study, microscopic haematuria and non-nephrotic proteinuria predicted the presence of NDRD among NIDDM patients presenting with renal disease.en_HK
dc.format.extent418 bytes-
dc.format.mimetypetext/html-
dc.languageengen_HK
dc.publisherOxford University Press. The Journal's web site is located at http://ndt.oxfordjournals.org/en_HK
dc.relation.ispartofNephrology Dialysis Transplantationen_HK
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.subjectMicroscopic haematuriaen_HK
dc.subjectNon-diabetic renal diseaseen_HK
dc.subjectNon-insulin dependent diabetes mellitusen_HK
dc.subjectNon-nephrotic proteinuriaen_HK
dc.titleClinical predictors of non-diabetic renal disease in patients with non-insulin dependent diabetes mellitusen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0931-0509&volume=12&issue=2&spage=2588&epage=2591&date=1997&atitle=Clinical+predictors+of+non-diabetic+renal+disease+in+patients+with+non-insulin+dependent+diabetes+mellitusen_HK
dc.identifier.emailChan, KW:hrmtckw@hku.hken_HK
dc.identifier.authorityChan, KW=rp00330en_HK
dc.description.naturepublished_or_final_versionen_HK
dc.identifier.doi10.1093/ndt/12.12.2588en_HK
dc.identifier.pmid9430856-
dc.identifier.scopuseid_2-s2.0-0030665196en_HK
dc.identifier.hkuros34130-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0030665196&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume12en_HK
dc.identifier.issue12en_HK
dc.identifier.spage2588en_HK
dc.identifier.epage2591en_HK
dc.identifier.isiWOS:000071054700022-
dc.publisher.placeUnited Kingdomen_HK

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