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Article: Hepatic resection for hepatocellular carcinoma: An audit of 343 patients

TitleHepatic resection for hepatocellular carcinoma: An audit of 343 patients
Authors
Issue Date1995
PublisherLippincott Williams & Wilkins. The Journal's web site is located at http://www.annalsofsurgery.com
Citation
Annals Of Surgery, 1995, v. 221 n. 3, p. 291-298 How to Cite?
AbstractObjective: The authors summarize the results of patients who had hepatectomy for hepatocellular carcinoma over a 22-year period. Summary Background Data: Recent reports showed improved perioperative results and long-term prognosis. Methods: The perioperative outcome of 343 patients was studied according to three different time periods: before 1987 (n = 149); 1987 to 1991 (n = 128); and 1992 to present (n = 66). Survival analysis was made by stratifying patients into two categories either before or after 1987. The majority of patients had large tumors (78%); cirrhosis (73%), and a major hepatectomy (73%). Results: Besides an increased resectability rate (23%), there was a marked reduction of the recent morbidity (32%; p < 0.001), operative (4.5%; NS) and hospital (6%; p < 0.02) mortality rates. The recent surgical approach was identified as a significant contributory factor to the lowered hospital mortality rate. Patients in the latter part of the study had significantly better survival, with a 1-, 3-and 5-year survival rate of 68%, 45%, and 35%, respectively. Early detection and effective treatment of recurrences contributed to the improved prognosis. Conclusions: The recent management strategy and technological advances improved the results of surgical treatment for patients with hepatocellular carcinoma.
Persistent Identifierhttp://hdl.handle.net/10722/49327
ISSN
2015 Impact Factor: 8.569
2015 SCImago Journal Rankings: 4.503
PubMed Central ID
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorLai, ECSen_HK
dc.contributor.authorFan, STen_HK
dc.contributor.authorLo, CMen_HK
dc.contributor.authorChu, KMen_HK
dc.contributor.authorLiu, CLen_HK
dc.contributor.authorWong, Jen_HK
dc.date.accessioned2008-06-12T06:39:34Z-
dc.date.available2008-06-12T06:39:34Z-
dc.date.issued1995en_HK
dc.identifier.citationAnnals Of Surgery, 1995, v. 221 n. 3, p. 291-298en_HK
dc.identifier.issn0003-4932en_HK
dc.identifier.urihttp://hdl.handle.net/10722/49327-
dc.description.abstractObjective: The authors summarize the results of patients who had hepatectomy for hepatocellular carcinoma over a 22-year period. Summary Background Data: Recent reports showed improved perioperative results and long-term prognosis. Methods: The perioperative outcome of 343 patients was studied according to three different time periods: before 1987 (n = 149); 1987 to 1991 (n = 128); and 1992 to present (n = 66). Survival analysis was made by stratifying patients into two categories either before or after 1987. The majority of patients had large tumors (78%); cirrhosis (73%), and a major hepatectomy (73%). Results: Besides an increased resectability rate (23%), there was a marked reduction of the recent morbidity (32%; p < 0.001), operative (4.5%; NS) and hospital (6%; p < 0.02) mortality rates. The recent surgical approach was identified as a significant contributory factor to the lowered hospital mortality rate. Patients in the latter part of the study had significantly better survival, with a 1-, 3-and 5-year survival rate of 68%, 45%, and 35%, respectively. Early detection and effective treatment of recurrences contributed to the improved prognosis. Conclusions: The recent management strategy and technological advances improved the results of surgical treatment for patients with hepatocellular carcinoma.en_HK
dc.format.extent388 bytes-
dc.format.mimetypetext/html-
dc.languageengen_HK
dc.publisherLippincott Williams & Wilkins. The Journal's web site is located at http://www.annalsofsurgery.comen_HK
dc.relation.ispartofAnnals of Surgeryen_HK
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.subject.meshCarcinoma, hepatocellular - mortality - surgeryen_HK
dc.subject.meshHepatectomyen_HK
dc.subject.meshLiver neoplasms - mortality - surgeryen_HK
dc.subject.meshMiddle ageden_HK
dc.subject.meshSurvival rateen_HK
dc.titleHepatic resection for hepatocellular carcinoma: An audit of 343 patientsen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0003-4932&volume=221&issue=3&spage=291&epage=298&date=1995&atitle=Hepatic+resection+for+hepatocellular+carcinoma:+an+audit+of+343+patientsen_HK
dc.identifier.emailFan, ST: stfan@hku.hken_HK
dc.identifier.emailLo, CM: chungmlo@hkucc.hku.hken_HK
dc.identifier.emailChu, KM: chukm@hkucc.hku.hken_HK
dc.identifier.emailWong, J: jwong@hkucc.hku.hken_HK
dc.identifier.authorityFan, ST=rp00355en_HK
dc.identifier.authorityLo, CM=rp00412en_HK
dc.identifier.authorityChu, KM=rp00435en_HK
dc.identifier.authorityWong, J=rp00322en_HK
dc.description.naturepublished_or_final_versionen_HK
dc.identifier.doi10.1097/00000658-199503000-00012-
dc.identifier.pmid7717783-
dc.identifier.pmcidPMC1234572en_HK
dc.identifier.scopuseid_2-s2.0-0028965102en_HK
dc.identifier.hkuros3688-
dc.identifier.volume221en_HK
dc.identifier.issue3en_HK
dc.identifier.spage291en_HK
dc.identifier.epage298en_HK
dc.identifier.isiWOS:A1995QL97700012-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridLai, ECS=36932159600en_HK
dc.identifier.scopusauthoridFan, ST=7402678224en_HK
dc.identifier.scopusauthoridLo, CM=7401771672en_HK
dc.identifier.scopusauthoridChu, KM=7402453538en_HK
dc.identifier.scopusauthoridLiu, CL=7409789712en_HK
dc.identifier.scopusauthoridWong, J=8049324500en_HK

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