File Download
  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Endoscopic retrograde cholangiopancreatography and endoscopic endoprosthesis insertion in patients with Klatskin tumors

TitleEndoscopic retrograde cholangiopancreatography and endoscopic endoprosthesis insertion in patients with Klatskin tumors
Authors
Issue Date1998
PublisherAmerican Medical Association. The Journal's web site is located at http://www.archsurg.com
Citation
Archives Of Surgery, 1998, v. 133 n. 3, p. 293-296 How to Cite?
AbstractObjective: To assess the value and the associated morbidity of endoscopic retrograde cholangiopancreatography (ERCP) and endoscopic endoprosthesis insertion in the treatment of patients with Klatskin tumors. Design: Retrospective study. Setting: A tertiary referral center. Patients: Fifty-five consecutive patients with Klatskin tumors diagnosed through typical cholangiographic and computed tomographic findings. Intervention: Standard ERCP with endoscopic stenting technique was employed. Once the diagnosis of Klatskin tumor was confirmed on cholangiogram, endoscopic stenting was performed to bypass the stricture. Multiple stents were inserted if necessary to ensure adequate biliary drainage. Main Outcome Measures: The success rate of ERCP and endoscopic endoprosthesis insertion, successful drainage rate, early complications of endoscopic procedure, procedure- related mortality, and long-term outcome of endoprosthesis. Results: Of the 55 patients, cholangiography was performed in 53 (96%). In the 49 patients in whom endoscopic stenting was attempted, the procedure was successful in 28 patients (57%) at the first attempt and 8 patients (16%) at the second attempt, resulting in a cumulative success rate of 73%. Only 20 of these patients had satisfactory biliary drainage, resulting in an overall successful drainage rate of 41%. Early complications, including acute cholangitis, acute pancreatitis, and post-papillotomy bleeding occurred in 14 patients (25%). Three patients (5%) died of procedure-related complications. The median patency of the first endoprosthesis inserted was 1 week (range, 0- 8 wk). The 30-day mortality rate was 18%. Conclusions: In patients with Klatskin tumors, ERCP and endoscopic endoprosthesis insertion have a low successful drainage rate, are associated with high morbidity and procedure- related mortality, and have a limited effect on long-term palliation. Endoscopic retrograde cholangiopancreatography and endoscopic endoprosthesis insertion have a limited value in the management of patients with Klatskin tumors.
Persistent Identifierhttp://hdl.handle.net/10722/49322
ISSN
2014 Impact Factor: 4.926
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorLiu, CLen_HK
dc.contributor.authorLo, CMen_HK
dc.contributor.authorLai, ECSen_HK
dc.contributor.authorFan, STen_HK
dc.date.accessioned2008-06-12T06:39:28Z-
dc.date.available2008-06-12T06:39:28Z-
dc.date.issued1998en_HK
dc.identifier.citationArchives Of Surgery, 1998, v. 133 n. 3, p. 293-296en_HK
dc.identifier.issn0004-0010en_HK
dc.identifier.urihttp://hdl.handle.net/10722/49322-
dc.description.abstractObjective: To assess the value and the associated morbidity of endoscopic retrograde cholangiopancreatography (ERCP) and endoscopic endoprosthesis insertion in the treatment of patients with Klatskin tumors. Design: Retrospective study. Setting: A tertiary referral center. Patients: Fifty-five consecutive patients with Klatskin tumors diagnosed through typical cholangiographic and computed tomographic findings. Intervention: Standard ERCP with endoscopic stenting technique was employed. Once the diagnosis of Klatskin tumor was confirmed on cholangiogram, endoscopic stenting was performed to bypass the stricture. Multiple stents were inserted if necessary to ensure adequate biliary drainage. Main Outcome Measures: The success rate of ERCP and endoscopic endoprosthesis insertion, successful drainage rate, early complications of endoscopic procedure, procedure- related mortality, and long-term outcome of endoprosthesis. Results: Of the 55 patients, cholangiography was performed in 53 (96%). In the 49 patients in whom endoscopic stenting was attempted, the procedure was successful in 28 patients (57%) at the first attempt and 8 patients (16%) at the second attempt, resulting in a cumulative success rate of 73%. Only 20 of these patients had satisfactory biliary drainage, resulting in an overall successful drainage rate of 41%. Early complications, including acute cholangitis, acute pancreatitis, and post-papillotomy bleeding occurred in 14 patients (25%). Three patients (5%) died of procedure-related complications. The median patency of the first endoprosthesis inserted was 1 week (range, 0- 8 wk). The 30-day mortality rate was 18%. Conclusions: In patients with Klatskin tumors, ERCP and endoscopic endoprosthesis insertion have a low successful drainage rate, are associated with high morbidity and procedure- related mortality, and have a limited effect on long-term palliation. Endoscopic retrograde cholangiopancreatography and endoscopic endoprosthesis insertion have a limited value in the management of patients with Klatskin tumors.en_HK
dc.format.extent418 bytes-
dc.format.mimetypetext/html-
dc.languageengen_HK
dc.publisherAmerican Medical Association. The Journal's web site is located at http://www.archsurg.comen_HK
dc.relation.ispartofArchives of Surgeryen_HK
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.subject.meshBile Duct Neoplasms - radiography - surgeryen_HK
dc.subject.meshCholangiopancreatography, Endoscopic Retrograde - adverse effects - mortalityen_HK
dc.subject.meshHepatic Duct, Common - radiography - surgeryen_HK
dc.subject.meshKlatskin's Tumor - radiography - surgeryen_HK
dc.subject.meshStents - adverse effectsen_HK
dc.titleEndoscopic retrograde cholangiopancreatography and endoscopic endoprosthesis insertion in patients with Klatskin tumorsen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0004-0010&volume=133&issue=3&spage=293&epage=296&date=1998&atitle=Endoscopic+retrograde+cholangiopancreatography+and+endoscopic+endoprosthesis+insertion+in+patients+with+Klatskin+tumorsen_HK
dc.identifier.emailLo, CM: chungmlo@hkucc.hku.hken_HK
dc.identifier.emailFan, ST: stfan@hku.hken_HK
dc.identifier.authorityLo, CM=rp00412en_HK
dc.identifier.authorityFan, ST=rp00355en_HK
dc.description.naturepublished_or_final_versionen_HK
dc.identifier.doi10.1001/archsurg.133.3.293en_HK
dc.identifier.pmid9517743-
dc.identifier.scopuseid_2-s2.0-0031978913en_HK
dc.identifier.hkuros32697-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0031978913&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume133en_HK
dc.identifier.issue3en_HK
dc.identifier.spage293en_HK
dc.identifier.epage296en_HK
dc.identifier.isiWOS:000072533900014-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridLiu, CL=7409789712en_HK
dc.identifier.scopusauthoridLo, CM=7401771672en_HK
dc.identifier.scopusauthoridLai, ECS=55187394300en_HK
dc.identifier.scopusauthoridFan, ST=7402678224en_HK

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats