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Article: Transferable hyperproduction of TEM-1 β-lactamase in Shigella flexneri due to a point mutation in the pribnow box

TitleTransferable hyperproduction of TEM-1 β-lactamase in Shigella flexneri due to a point mutation in the pribnow box
Authors
Issue Date1997
PublisherAmerican Society for Microbiology.
Citation
Antimicrobial Agents And Chemotherapy, 1997, v. 41 n. 2, p. 468-470 How to Cite?
AbstractTEM-1 hyperproduction in two ampicillin-sulbactam-resistant Shigella flexneri strains was studied. In both strains the bla(TEM) gene was encoded as a single copy on a large conjugatively transferable plasmid. A single G→T transversion at position 1 of the - 10 consensus sequence was identified to be the mechanism of TEM-1 hyperproduction.
Persistent Identifierhttp://hdl.handle.net/10722/49179
ISSN
2015 Impact Factor: 4.415
2015 SCImago Journal Rankings: 2.322
PubMed Central ID
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorSiu, LKen_HK
dc.contributor.authorHo, PLen_HK
dc.contributor.authorYuen, KYen_HK
dc.contributor.authorWong, SSYen_HK
dc.contributor.authorChau, PYen_HK
dc.date.accessioned2008-06-12T06:36:10Z-
dc.date.available2008-06-12T06:36:10Z-
dc.date.issued1997en_HK
dc.identifier.citationAntimicrobial Agents And Chemotherapy, 1997, v. 41 n. 2, p. 468-470en_HK
dc.identifier.issn0066-4804en_HK
dc.identifier.urihttp://hdl.handle.net/10722/49179-
dc.description.abstractTEM-1 hyperproduction in two ampicillin-sulbactam-resistant Shigella flexneri strains was studied. In both strains the bla(TEM) gene was encoded as a single copy on a large conjugatively transferable plasmid. A single G→T transversion at position 1 of the - 10 consensus sequence was identified to be the mechanism of TEM-1 hyperproduction.en_HK
dc.format.extent418 bytes-
dc.format.mimetypetext/html-
dc.languageengen_HK
dc.publisherAmerican Society for Microbiology.en_HK
dc.relation.ispartofAntimicrobial Agents and Chemotherapyen_HK
dc.rightsAntimicrobial Agents and Chemotherapy. Copyright © American Society for Microbiology.en_HK
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.rightsCopyright © American Society for Microbiology, Antimicrobial Agents and Chemotherapy, 1997, v. 41 n. 2, p. 468-470en_HK
dc.subject.meshGenes, Bacterial - geneticsen_HK
dc.subject.meshShigella flexneri - drug effects - enzymology - isolation & purificationen_HK
dc.subject.meshbeta-Lactamases - genetics - metabolismen_HK
dc.subject.meshAnti-Bacterial Agents - pharmacologyen_HK
dc.subject.meshBase Sequenceen_HK
dc.titleTransferable hyperproduction of TEM-1 β-lactamase in Shigella flexneri due to a point mutation in the pribnow boxen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0066-4804&volume=41&issue=2&spage=468&epage=470&date=1997&atitle=Transferable+hyperproduction+of+TEM-1+β-lactamase+in+Shigella+flexneri+due+to+a+point+mutation+in+the+pribnow+boxen_HK
dc.identifier.emailHo, PL:plho@hkucc.hku.hken_HK
dc.identifier.emailYuen, KY:kyyuen@hkucc.hku.hken_HK
dc.identifier.emailWong, SSY:samsonsy@hkucc.hku.hken_HK
dc.identifier.authorityHo, PL=rp00406en_HK
dc.identifier.authorityYuen, KY=rp00366en_HK
dc.identifier.authorityWong, SSY=rp00395en_HK
dc.description.naturepublished_or_final_versionen_HK
dc.identifier.pmid9021210-
dc.identifier.pmcidPMC163732-
dc.identifier.scopuseid_2-s2.0-0031046151en_HK
dc.identifier.volume41en_HK
dc.identifier.issue2en_HK
dc.identifier.spage468en_HK
dc.identifier.epage470en_HK
dc.identifier.isiWOS:A1997WG30300040-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridSiu, LK=7006651154en_HK
dc.identifier.scopusauthoridHo, PL=7402211363en_HK
dc.identifier.scopusauthoridYuen, KY=36078079100en_HK
dc.identifier.scopusauthoridWong, SSY=13310021400en_HK
dc.identifier.scopusauthoridChau, PY=36509704300en_HK

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