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- Publisher Website: 10.1128/AAC.41.2.468
- Scopus: eid_2-s2.0-0031046151
- PMID: 9021210
- WOS: WOS:A1997WG30300040
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Article: Transferable hyperproduction of TEM-1 β-lactamase in Shigella flexneri due to a point mutation in the pribnow box
Title | Transferable hyperproduction of TEM-1 β-lactamase in Shigella flexneri due to a point mutation in the pribnow box |
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Authors | |
Issue Date | 1997 |
Publisher | American Society for Microbiology. |
Citation | Antimicrobial Agents And Chemotherapy, 1997, v. 41 n. 2, p. 468-470 How to Cite? |
Abstract | TEM-1 hyperproduction in two ampicillin-sulbactam-resistant Shigella flexneri strains was studied. In both strains the bla(TEM) gene was encoded as a single copy on a large conjugatively transferable plasmid. A single G→T transversion at position 1 of the - 10 consensus sequence was identified to be the mechanism of TEM-1 hyperproduction. |
Persistent Identifier | http://hdl.handle.net/10722/49179 |
ISSN | 2023 Impact Factor: 4.1 2023 SCImago Journal Rankings: 1.357 |
PubMed Central ID | |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Siu, LK | en_HK |
dc.contributor.author | Ho, PL | en_HK |
dc.contributor.author | Yuen, KY | en_HK |
dc.contributor.author | Wong, SSY | en_HK |
dc.contributor.author | Chau, PY | en_HK |
dc.date.accessioned | 2008-06-12T06:36:10Z | - |
dc.date.available | 2008-06-12T06:36:10Z | - |
dc.date.issued | 1997 | en_HK |
dc.identifier.citation | Antimicrobial Agents And Chemotherapy, 1997, v. 41 n. 2, p. 468-470 | en_HK |
dc.identifier.issn | 0066-4804 | en_HK |
dc.identifier.uri | http://hdl.handle.net/10722/49179 | - |
dc.description.abstract | TEM-1 hyperproduction in two ampicillin-sulbactam-resistant Shigella flexneri strains was studied. In both strains the bla(TEM) gene was encoded as a single copy on a large conjugatively transferable plasmid. A single G→T transversion at position 1 of the - 10 consensus sequence was identified to be the mechanism of TEM-1 hyperproduction. | en_HK |
dc.format.extent | 418 bytes | - |
dc.format.mimetype | text/html | - |
dc.language | eng | en_HK |
dc.publisher | American Society for Microbiology. | en_HK |
dc.relation.ispartof | Antimicrobial Agents and Chemotherapy | en_HK |
dc.rights | Antimicrobial Agents and Chemotherapy. Copyright © American Society for Microbiology. | en_HK |
dc.rights | Copyright © American Society for Microbiology, Antimicrobial Agents and Chemotherapy, 1997, v. 41 n. 2, p. 468-470 | en_HK |
dc.subject.mesh | Genes, Bacterial - genetics | en_HK |
dc.subject.mesh | Shigella flexneri - drug effects - enzymology - isolation & purification | en_HK |
dc.subject.mesh | beta-Lactamases - genetics - metabolism | en_HK |
dc.subject.mesh | Anti-Bacterial Agents - pharmacology | en_HK |
dc.subject.mesh | Base Sequence | en_HK |
dc.title | Transferable hyperproduction of TEM-1 β-lactamase in Shigella flexneri due to a point mutation in the pribnow box | en_HK |
dc.type | Article | en_HK |
dc.identifier.openurl | http://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0066-4804&volume=41&issue=2&spage=468&epage=470&date=1997&atitle=Transferable+hyperproduction+of+TEM-1+β-lactamase+in+Shigella+flexneri+due+to+a+point+mutation+in+the+pribnow+box | en_HK |
dc.identifier.email | Ho, PL:plho@hkucc.hku.hk | en_HK |
dc.identifier.email | Yuen, KY:kyyuen@hkucc.hku.hk | en_HK |
dc.identifier.email | Wong, SSY:samsonsy@hkucc.hku.hk | en_HK |
dc.identifier.authority | Ho, PL=rp00406 | en_HK |
dc.identifier.authority | Yuen, KY=rp00366 | en_HK |
dc.identifier.authority | Wong, SSY=rp00395 | en_HK |
dc.description.nature | published_or_final_version | en_HK |
dc.identifier.doi | 10.1128/AAC.41.2.468 | - |
dc.identifier.pmid | 9021210 | - |
dc.identifier.pmcid | PMC163732 | - |
dc.identifier.scopus | eid_2-s2.0-0031046151 | en_HK |
dc.identifier.volume | 41 | en_HK |
dc.identifier.issue | 2 | en_HK |
dc.identifier.spage | 468 | en_HK |
dc.identifier.epage | 470 | en_HK |
dc.identifier.isi | WOS:A1997WG30300040 | - |
dc.publisher.place | United States | en_HK |
dc.identifier.scopusauthorid | Siu, LK=7006651154 | en_HK |
dc.identifier.scopusauthorid | Ho, PL=7402211363 | en_HK |
dc.identifier.scopusauthorid | Yuen, KY=36078079100 | en_HK |
dc.identifier.scopusauthorid | Wong, SSY=13310021400 | en_HK |
dc.identifier.scopusauthorid | Chau, PY=36509704300 | en_HK |
dc.identifier.issnl | 0066-4804 | - |