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Article: Molecular characterization of isoniazid resistance in Mycobacterium tuberculosis: Identification of a novel mutation in inhA

TitleMolecular characterization of isoniazid resistance in Mycobacterium tuberculosis: Identification of a novel mutation in inhA
Authors
Issue Date2006
PublisherAmerican Society for Microbiology.
Citation
Antimicrobial Agents And Chemotherapy, 2006, v. 50 n. 3, p. 1075-1078 How to Cite?
AbstractMultiplex allele-specific PCRs detecting katG codon 315 and mabA (bp -15) mutations could specifically identify 77.5% of isoniazid-resistant Mycobacterium tuberculosis strains in the South China region. One clinical isolate harboring InhA Ile194Thr was characterized to show strong association with isoniazid resistance in Mycobacterium tuberculosis. Copyright © 2006, American Society for Microbiology. All Rights Reserved.
Persistent Identifierhttp://hdl.handle.net/10722/49176
ISSN
2015 Impact Factor: 4.415
2015 SCImago Journal Rankings: 2.322
PubMed Central ID
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorLeung, ETYen_HK
dc.contributor.authorHo, PLen_HK
dc.contributor.authorYuen, KYen_HK
dc.contributor.authorWoo, WLen_HK
dc.contributor.authorLam, THen_HK
dc.contributor.authorKao, RYen_HK
dc.contributor.authorSeto, WHen_HK
dc.contributor.authorYam, WCen_HK
dc.date.accessioned2008-06-12T06:36:06Z-
dc.date.available2008-06-12T06:36:06Z-
dc.date.issued2006en_HK
dc.identifier.citationAntimicrobial Agents And Chemotherapy, 2006, v. 50 n. 3, p. 1075-1078en_HK
dc.identifier.issn0066-4804en_HK
dc.identifier.urihttp://hdl.handle.net/10722/49176-
dc.description.abstractMultiplex allele-specific PCRs detecting katG codon 315 and mabA (bp -15) mutations could specifically identify 77.5% of isoniazid-resistant Mycobacterium tuberculosis strains in the South China region. One clinical isolate harboring InhA Ile194Thr was characterized to show strong association with isoniazid resistance in Mycobacterium tuberculosis. Copyright © 2006, American Society for Microbiology. All Rights Reserved.en_HK
dc.format.extent388 bytes-
dc.format.mimetypetext/html-
dc.languageengen_HK
dc.publisherAmerican Society for Microbiology.en_HK
dc.relation.ispartofAntimicrobial Agents and Chemotherapyen_HK
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.rightsAntimicrobial Agents and Chemotherapy. Copyright © American Society for Microbiology.en_HK
dc.rightsCopyright © American Society for Microbiology, Antimicrobial Agents and Chemotherapy, 2006, v. 50 n. 3, p. 1075-1078en_HK
dc.subject.meshAntitubercular Agents - pharmacologyen_HK
dc.subject.meshBacterial Proteins - geneticsen_HK
dc.subject.meshGenes, Bacterialen_HK
dc.subject.meshIsoniazid - pharmacologyen_HK
dc.subject.meshMycobacterium tuberculosis - drug effects - genetics - isolation & purificationen_HK
dc.titleMolecular characterization of isoniazid resistance in Mycobacterium tuberculosis: Identification of a novel mutation in inhAen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0066-4804&volume=50&issue=3&spage=1075&epage=1078&date=2006&atitle=Molecular+characterization+of+isoniazid+resistance+in+Mycobacterium+tuberculosis:+identification+of+a+novel+mutation+in+inhAen_HK
dc.identifier.emailHo, PL:plho@hkucc.hku.hken_HK
dc.identifier.emailYuen, KY:kyyuen@hkucc.hku.hken_HK
dc.identifier.emailLam, TH:hrmrlth@hkucc.hku.hken_HK
dc.identifier.emailKao, RY:rytkao@hkucc.hku.hken_HK
dc.identifier.emailYam, WC:wcyam@hkucc.hku.hken_HK
dc.identifier.authorityHo, PL=rp00406en_HK
dc.identifier.authorityYuen, KY=rp00366en_HK
dc.identifier.authorityLam, TH=rp00326en_HK
dc.identifier.authorityKao, RY=rp00481en_HK
dc.identifier.authorityYam, WC=rp00313en_HK
dc.description.naturepublished_or_final_versionen_HK
dc.identifier.doi10.1128/AAC.50.3.1075-1078.2006en_HK
dc.identifier.pmid16495272-
dc.identifier.pmcidPMC1426451en_HK
dc.identifier.scopuseid_2-s2.0-33644680148en_HK
dc.identifier.hkuros118626-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-33644680148&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume50en_HK
dc.identifier.issue3en_HK
dc.identifier.spage1075en_HK
dc.identifier.epage1078en_HK
dc.identifier.isiWOS:000235786300034-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridLeung, ETY=26661142200en_HK
dc.identifier.scopusauthoridHo, PL=7402211363en_HK
dc.identifier.scopusauthoridYuen, KY=36078079100en_HK
dc.identifier.scopusauthoridWoo, WL=12765205700en_HK
dc.identifier.scopusauthoridLam, TH=7202522876en_HK
dc.identifier.scopusauthoridKao, RY=7101675499en_HK
dc.identifier.scopusauthoridSeto, WH=7005799377en_HK
dc.identifier.scopusauthoridYam, WC=7004281720en_HK

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