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Article: Autologous bone marrow transplantation for primary nasal T/NK cell lymphoma

TitleAutologous bone marrow transplantation for primary nasal T/NK cell lymphoma
Authors
KeywordsAutologous bone marrow transplantation
Nasal lymphoma
Issue Date1997
PublisherNature Publishing Group. The Journal's web site is located at http://www.nature.com/bmt
Citation
Bone Marrow Transplantation, 1997, v. 19 n. 1, p. 91-93 How to Cite?
AbstractPrimary nasal T or NK cell lymphoma is rarely seen in the Western population but is more common in the Orientals. Although it often presents with localized disease, the prognosis is generally poor. Long-term remission is seen in only 50% of patients with stage I disease despite aggressive treatment with chemotherapy and radiotherapy, and is invariably fatal if disseminated. Conventional chemotherapy for relapsed disease is usually not successful. Since 1992, three patients with relapsed primary nasal T/NK cell lymphoma have received high-dose chemotherapy with autologous bone marrow rescue at Queen Mary Hospital, Hong Kong. High-dose cyclophosphamide, BCNU and etoposide were used for conditioning. Two of them had a favourable response and remained in complete remission at 12 and 44 months post-transplant. The third patient unfortunately had a systemic relapse 6 months after the transplant. It appears from this experience that, like other aggressive non-Hodgkin's lymphomas, high-dose chemotherapy and autologous bone marrow rescue is an effective treatment for relapsed primary nasal lymphoma following failure of conventional chemotherapy and radiotherapy.
Persistent Identifierhttp://hdl.handle.net/10722/49057
ISSN
2015 Impact Factor: 3.636
2015 SCImago Journal Rankings: 1.585
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorLiang, Ren_HK
dc.contributor.authorChen, Fen_HK
dc.contributor.authorLee, CKen_HK
dc.contributor.authorKwong, YLen_HK
dc.contributor.authorChim, CSen_HK
dc.contributor.authorYau, CCen_HK
dc.contributor.authorChiu, Een_HK
dc.date.accessioned2008-06-12T06:33:29Z-
dc.date.available2008-06-12T06:33:29Z-
dc.date.issued1997en_HK
dc.identifier.citationBone Marrow Transplantation, 1997, v. 19 n. 1, p. 91-93en_HK
dc.identifier.issn0268-3369en_HK
dc.identifier.urihttp://hdl.handle.net/10722/49057-
dc.description.abstractPrimary nasal T or NK cell lymphoma is rarely seen in the Western population but is more common in the Orientals. Although it often presents with localized disease, the prognosis is generally poor. Long-term remission is seen in only 50% of patients with stage I disease despite aggressive treatment with chemotherapy and radiotherapy, and is invariably fatal if disseminated. Conventional chemotherapy for relapsed disease is usually not successful. Since 1992, three patients with relapsed primary nasal T/NK cell lymphoma have received high-dose chemotherapy with autologous bone marrow rescue at Queen Mary Hospital, Hong Kong. High-dose cyclophosphamide, BCNU and etoposide were used for conditioning. Two of them had a favourable response and remained in complete remission at 12 and 44 months post-transplant. The third patient unfortunately had a systemic relapse 6 months after the transplant. It appears from this experience that, like other aggressive non-Hodgkin's lymphomas, high-dose chemotherapy and autologous bone marrow rescue is an effective treatment for relapsed primary nasal lymphoma following failure of conventional chemotherapy and radiotherapy.en_HK
dc.format.extent418 bytes-
dc.format.mimetypetext/html-
dc.languageengen_HK
dc.publisherNature Publishing Group. The Journal's web site is located at http://www.nature.com/bmten_HK
dc.relation.ispartofBone Marrow Transplantationen_HK
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.subjectAutologous bone marrow transplantationen_HK
dc.subjectNasal lymphomaen_HK
dc.titleAutologous bone marrow transplantation for primary nasal T/NK cell lymphomaen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0268-3369&volume=19&issue=1&spage=91&epage=93&date=1997&atitle=Autologous+bone+marrow+transplantation+for+primary+nasal+T/NK+cell+lymphomaen_HK
dc.identifier.emailLiang, R:rliang@hku.hken_HK
dc.identifier.emailKwong, YL:ylkwong@hku.hken_HK
dc.identifier.emailChim, CS:jcschim@hku.hken_HK
dc.identifier.authorityLiang, R=rp00345en_HK
dc.identifier.authorityKwong, YL=rp00358en_HK
dc.identifier.authorityChim, CS=rp00408en_HK
dc.description.naturepublished_or_final_versionen_HK
dc.identifier.doi10.1038/sj.bmt.1700606en_HK
dc.identifier.pmid9012939-
dc.identifier.scopuseid_2-s2.0-0031029609en_HK
dc.identifier.hkuros22806-
dc.identifier.hkuros29866-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0031029609&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume19en_HK
dc.identifier.issue1en_HK
dc.identifier.spage91en_HK
dc.identifier.epage93en_HK
dc.identifier.isiWOS:A1997WC70200017-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridLiang, R=26643224900en_HK
dc.identifier.scopusauthoridChen, F=25928259900en_HK
dc.identifier.scopusauthoridLee, CK=36882474000en_HK
dc.identifier.scopusauthoridKwong, YL=7102818954en_HK
dc.identifier.scopusauthoridChim, CS=7004597253en_HK
dc.identifier.scopusauthoridYau, CC=7007038422en_HK
dc.identifier.scopusauthoridChiu, E=24827833600en_HK

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