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Article: Operative outcomes of adult-to-adult right lobe live donor liver transplantation: A comparative study with cadaveric whole-graft liver transplantation in a single center

TitleOperative outcomes of adult-to-adult right lobe live donor liver transplantation: A comparative study with cadaveric whole-graft liver transplantation in a single center
Authors
Issue Date2006
PublisherLippincott Williams & Wilkins. The Journal's web site is located at http://www.annalsofsurgery.com
Citation
Annals Of Surgery, 2006, v. 243 n. 3, p. 404-410 How to Cite?
AbstractObjective: To evaluate and compare the operative and survival outcomes of patients who underwent right lobe live donor liver transplantation (RLDLT) and cadaveric whole-graft liver transplant (CWLT) recipients in a single institution. Summary Background Data: Current data suggest that RLDLT has an inferior graft survival outcome when compared with CWLT. Patients and Methods: A prospective study was performed on 180 consecutive adult patients who underwent primary liver transplantation from January 2000 to February 2004. The operative and survival outcomes of RLDLT (n = 124) were compared with those of CWLT (n = 56). Results: Fifty-five (44%) and 16 (29%) patients were on high-urgency list in the RLDLT group and the CWLT group, respectively (P = 0.045). The preoperative Model for End-Stage Liver Disease scores were comparable in both groups. The waiting time for liver transplantation was significantly shorter in the RLDLT group. The graft weight to estimated standard liver weight ratio was significantly lower in the RLDLT group. The postoperative hospital stay and hospital mortality were comparable in the RLDLT group (1.6%) and the CWLT group (5.4%). Thirty-one (25%) patients in the RLDLT group and 3 (5%) patients in the CWLT group developed biliary stricture on follow-up (P = 0.002). At a median follow-up of 27 months, the actuarial graft and patient survival rates were 88% and 90%, respectively, in the RLDLT group, and both were 84% in the CWLT group. Conclusion: RLDLT results in favorable operative outcomes comparable with those of CWLT. However, there is a significantly higher incidence of biliary stricture associated with RLDLT. Copyright © 2006 by Lippincott Williams & Wilkins.
Persistent Identifierhttp://hdl.handle.net/10722/48938
ISSN
2015 Impact Factor: 8.569
2015 SCImago Journal Rankings: 4.503
PubMed Central ID
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorLiu, CLen_HK
dc.contributor.authorFan, STen_HK
dc.contributor.authorLo, CMen_HK
dc.contributor.authorWei, WIen_HK
dc.contributor.authorChan, SCen_HK
dc.contributor.authorYong, BHen_HK
dc.contributor.authorWong, Jen_HK
dc.date.accessioned2008-06-12T06:30:11Z-
dc.date.available2008-06-12T06:30:11Z-
dc.date.issued2006en_HK
dc.identifier.citationAnnals Of Surgery, 2006, v. 243 n. 3, p. 404-410en_HK
dc.identifier.issn0003-4932en_HK
dc.identifier.urihttp://hdl.handle.net/10722/48938-
dc.description.abstractObjective: To evaluate and compare the operative and survival outcomes of patients who underwent right lobe live donor liver transplantation (RLDLT) and cadaveric whole-graft liver transplant (CWLT) recipients in a single institution. Summary Background Data: Current data suggest that RLDLT has an inferior graft survival outcome when compared with CWLT. Patients and Methods: A prospective study was performed on 180 consecutive adult patients who underwent primary liver transplantation from January 2000 to February 2004. The operative and survival outcomes of RLDLT (n = 124) were compared with those of CWLT (n = 56). Results: Fifty-five (44%) and 16 (29%) patients were on high-urgency list in the RLDLT group and the CWLT group, respectively (P = 0.045). The preoperative Model for End-Stage Liver Disease scores were comparable in both groups. The waiting time for liver transplantation was significantly shorter in the RLDLT group. The graft weight to estimated standard liver weight ratio was significantly lower in the RLDLT group. The postoperative hospital stay and hospital mortality were comparable in the RLDLT group (1.6%) and the CWLT group (5.4%). Thirty-one (25%) patients in the RLDLT group and 3 (5%) patients in the CWLT group developed biliary stricture on follow-up (P = 0.002). At a median follow-up of 27 months, the actuarial graft and patient survival rates were 88% and 90%, respectively, in the RLDLT group, and both were 84% in the CWLT group. Conclusion: RLDLT results in favorable operative outcomes comparable with those of CWLT. However, there is a significantly higher incidence of biliary stricture associated with RLDLT. Copyright © 2006 by Lippincott Williams & Wilkins.en_HK
dc.format.extent388 bytes-
dc.format.mimetypetext/html-
dc.languageengen_HK
dc.publisherLippincott Williams & Wilkins. The Journal's web site is located at http://www.annalsofsurgery.comen_HK
dc.relation.ispartofAnnals of Surgeryen_HK
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.subject.meshLiver Failure - surgeryen_HK
dc.subject.meshLiver Transplantation - methods - mortalityen_HK
dc.subject.meshLiving Donorsen_HK
dc.subject.meshCadaveren_HK
dc.subject.meshFollow-Up Studiesen_HK
dc.titleOperative outcomes of adult-to-adult right lobe live donor liver transplantation: A comparative study with cadaveric whole-graft liver transplantation in a single centeren_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0003-4932&volume=243&issue=3&spage=404&epage=410&date=2006&atitle=Operative+outcomes+of+adult-to-adult+right+lobe+live+donor+liver+transplantation:+a+comparative+study+with+cadaveric+whole-graft+liver+transplantation+in+a+single+centeren_HK
dc.identifier.emailFan, ST: stfan@hku.hken_HK
dc.identifier.emailLo, CM: chungmlo@hkucc.hku.hken_HK
dc.identifier.emailWei, WI: hrmswwi@hku.hken_HK
dc.identifier.emailChan, SC: chanlsc@hkucc.hku.hken_HK
dc.identifier.emailWong, J: jwong@hkucc.hku.hken_HK
dc.identifier.authorityFan, ST=rp00355en_HK
dc.identifier.authorityLo, CM=rp00412en_HK
dc.identifier.authorityWei, WI=rp00323en_HK
dc.identifier.authorityChan, SC=rp01568en_HK
dc.identifier.authorityWong, J=rp00322en_HK
dc.description.naturepublished_or_final_versionen_HK
dc.identifier.doi10.1097/01.sla.0000201544.36473.a2en_HK
dc.identifier.pmid16495707-
dc.identifier.pmcidPMC1448929en_HK
dc.identifier.scopuseid_2-s2.0-33644643747en_HK
dc.identifier.hkuros116496-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-33644643747&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume243en_HK
dc.identifier.issue3en_HK
dc.identifier.spage404en_HK
dc.identifier.epage410en_HK
dc.identifier.isiWOS:000235720600018-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridLiu, CL=7409789712en_HK
dc.identifier.scopusauthoridFan, ST=7402678224en_HK
dc.identifier.scopusauthoridLo, CM=7401771672en_HK
dc.identifier.scopusauthoridWei, WI=7403321552en_HK
dc.identifier.scopusauthoridChan, SC=7404255575en_HK
dc.identifier.scopusauthoridYong, BH=7003644314en_HK
dc.identifier.scopusauthoridWong, J=8049324500en_HK
dc.identifier.citeulike697939-

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