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Article: Effects of two different growth media on the postantifungal effect induced by polyenes on Candida species

TitleEffects of two different growth media on the postantifungal effect induced by polyenes on Candida species
Authors
Issue Date2001
PublisherAmerican Society for Microbiology.
Citation
Journal Of Clinical Microbiology, 2001, v. 39 n. 7, p. 2732-2735 How to Cite?
AbstractThere are no data on the effects of different growth media on polyene-induced postantifungal effect (PAFE) in Candida species. Hence, the nystatin- and amphotericin B-induced PAFEs in six Candida species (26 isolates) grown in Sabouraud's dextrose broth (SAB) and RPMI broth were evaluated, following limited exposure to the MICs of the two polyenes, using an automated turbidometric method. For nystatin, PAFE varied between 1.88 and 4.87 h in SAB and 0.66 and 6.89 h in RPMI, and for amphotericin B, the equivalent values were 3.13 to 10.98 h in SAB and 0.97 to 7.01 h in RPMI. These highly significant (P < 0.001) variations in the PAFE with both drugs, noted with most Candida strains grown in different media, call for standardization of intralaboratory methodology in measuring this parameter in order to obtain universally comparable data.
Persistent Identifierhttp://hdl.handle.net/10722/48932
ISSN
2015 Impact Factor: 3.631
2015 SCImago Journal Rankings: 2.151
PubMed Central ID
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorShu, Men_HK
dc.contributor.authorEllepola, ANBen_HK
dc.contributor.authorSamaranayake, LPen_HK
dc.date.accessioned2008-06-12T06:30:00Z-
dc.date.available2008-06-12T06:30:00Z-
dc.date.issued2001en_HK
dc.identifier.citationJournal Of Clinical Microbiology, 2001, v. 39 n. 7, p. 2732-2735en_HK
dc.identifier.issn0095-1137en_HK
dc.identifier.urihttp://hdl.handle.net/10722/48932-
dc.description.abstractThere are no data on the effects of different growth media on polyene-induced postantifungal effect (PAFE) in Candida species. Hence, the nystatin- and amphotericin B-induced PAFEs in six Candida species (26 isolates) grown in Sabouraud's dextrose broth (SAB) and RPMI broth were evaluated, following limited exposure to the MICs of the two polyenes, using an automated turbidometric method. For nystatin, PAFE varied between 1.88 and 4.87 h in SAB and 0.66 and 6.89 h in RPMI, and for amphotericin B, the equivalent values were 3.13 to 10.98 h in SAB and 0.97 to 7.01 h in RPMI. These highly significant (P < 0.001) variations in the PAFE with both drugs, noted with most Candida strains grown in different media, call for standardization of intralaboratory methodology in measuring this parameter in order to obtain universally comparable data.en_HK
dc.format.extent384 bytes-
dc.format.mimetypetext/html-
dc.languageengen_HK
dc.publisherAmerican Society for Microbiology.en_HK
dc.relation.ispartofJournal of Clinical Microbiologyen_HK
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.rightsJournal of Clinical Microbiology. Copyright © American Society for Microbiology.en_HK
dc.rightsCopyright © American Society for Microbiology, Journal of Clinical Microbiology, 2001, v. 39 n. 7, p. 2732-2735en_HK
dc.subject.meshAmphotericin B - pharmacologyen_HK
dc.subject.meshAntifungal Agents - pharmacologyen_HK
dc.subject.meshCandida - classification - drug effects - growth & developmenten_HK
dc.subject.meshNystatin - pharmacologyen_HK
dc.subject.meshPolyenes - pharmacologyen_HK
dc.titleEffects of two different growth media on the postantifungal effect induced by polyenes on Candida speciesen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0095-1137&volume=39&issue=7&spage=2732&epage=2735&date=2001&atitle=Effects+of+two+different+growth+media+on+the+postantifungal+effect+induced+by+polyenes+on+Candida+speciesen_HK
dc.identifier.emailSamaranayake, LP:lakshman@hku.hken_HK
dc.identifier.authoritySamaranayake, LP=rp00023en_HK
dc.description.naturepublished_or_final_versionen_HK
dc.identifier.doi10.1128/JCM.39.7.2732-2735.2001en_HK
dc.identifier.pmid11427609-
dc.identifier.pmcidPMC88225en_HK
dc.identifier.scopuseid_2-s2.0-0034964040en_HK
dc.identifier.hkuros62531-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0034964040&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume39en_HK
dc.identifier.issue7en_HK
dc.identifier.spage2732en_HK
dc.identifier.epage2735en_HK
dc.identifier.isiWOS:000169586400068-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridShu, M=7005890194en_HK
dc.identifier.scopusauthoridEllepola, ANB=6604060863en_HK
dc.identifier.scopusauthoridSamaranayake, LP=7102761002en_HK

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