File Download
  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Ectoplasmic specialization: A friend or a foe of spermatogenesis?

TitleEctoplasmic specialization: A friend or a foe of spermatogenesis?
Authors
KeywordsBiology
Issue Date2007
PublisherJohn Wiley & Sons Ltd. The Journal's web site is located at http://www.interscience.wiley.com/jpages/0265-9247/
Citation
Bioessays, 2007, v. 29 n. 1, p. 36-48 How to Cite?
AbstractThe ectoplasmic specialization (ES) is a testis-specific, actin-based hybrid anchoring and tight junction. It is confined to the interface between Sertoli cells at the blood-testis barrier, known as the basal ES, as well as between Sertoli cells and developing spermatids designated the apical ES. The ES shares features of adherens junctions, tight junctions and focal contacts. By adopting the best features of each junction type, this hybrid nature of ES facilitates the extensive junction-restructuring events in the seminiferous epithelium during spermatogenesis. For instance, the α6β1-integrin- laminin 333 complex, which is usually limited to the cell-matrix interface in other epithelia to facilitate cell movement, is a putative apical ES constituent. Furthermore, JAM-C and CAR, two tight junction integral membrane proteins, are also components of apical ES involving in spermatid orientation. We discuss herein the mechanisms that maintain the cross-talk between ES and blood-testis barrier to facilitate cell movement and orientation in the seminiferous epithelium. © 2006 Wiley Periodicals, Inc.
Persistent Identifierhttp://hdl.handle.net/10722/48722
ISSN
2015 Impact Factor: 4.725
2015 SCImago Journal Rankings: 3.104
PubMed Central ID
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorYan, HHNen_HK
dc.contributor.authorMruk, DDen_HK
dc.contributor.authorLee, WMen_HK
dc.contributor.authorCheng, CYen_HK
dc.date.accessioned2008-05-22T04:22:24Z-
dc.date.available2008-05-22T04:22:24Z-
dc.date.issued2007en_HK
dc.identifier.citationBioessays, 2007, v. 29 n. 1, p. 36-48en_HK
dc.identifier.issn0265-9247en_HK
dc.identifier.urihttp://hdl.handle.net/10722/48722-
dc.description.abstractThe ectoplasmic specialization (ES) is a testis-specific, actin-based hybrid anchoring and tight junction. It is confined to the interface between Sertoli cells at the blood-testis barrier, known as the basal ES, as well as between Sertoli cells and developing spermatids designated the apical ES. The ES shares features of adherens junctions, tight junctions and focal contacts. By adopting the best features of each junction type, this hybrid nature of ES facilitates the extensive junction-restructuring events in the seminiferous epithelium during spermatogenesis. For instance, the α6β1-integrin- laminin 333 complex, which is usually limited to the cell-matrix interface in other epithelia to facilitate cell movement, is a putative apical ES constituent. Furthermore, JAM-C and CAR, two tight junction integral membrane proteins, are also components of apical ES involving in spermatid orientation. We discuss herein the mechanisms that maintain the cross-talk between ES and blood-testis barrier to facilitate cell movement and orientation in the seminiferous epithelium. © 2006 Wiley Periodicals, Inc.en_HK
dc.format.extent446782 bytes-
dc.format.extent2457 bytes-
dc.format.mimetypeapplication/pdf-
dc.format.mimetypetext/plain-
dc.languageengen_HK
dc.publisherJohn Wiley & Sons Ltd. The Journal's web site is located at http://www.interscience.wiley.com/jpages/0265-9247/en_HK
dc.relation.ispartofBioEssaysen_HK
dc.rightsBioEssays. Copyright © John Wiley & Sons Ltd.en_HK
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.rightsThis is a preprint of an article published in BioEssays, 2007, v. 29 n. 1, p. 36-48en_HK
dc.subjectBiologyen_HK
dc.titleEctoplasmic specialization: A friend or a foe of spermatogenesis?en_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0265-9247&volume=29&issue=1&spage=36&epage=48&date=2007&atitle=Ectoplasmic+specialization:+a+friend+or+a+foe+of+spermatogenesis?en_HK
dc.identifier.emailLee, WM: hrszlwm@hku.hken_HK
dc.identifier.authorityLee, WM=rp00728en_HK
dc.description.naturepostprinten_HK
dc.identifier.doi10.1002/bies.20513en_HK
dc.identifier.pmid17187371-
dc.identifier.pmcidPMC2804921-
dc.identifier.scopuseid_2-s2.0-33846586935en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-33846586935&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume29en_HK
dc.identifier.issue1en_HK
dc.identifier.spage36en_HK
dc.identifier.epage48en_HK
dc.identifier.isiWOS:000243336700006-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridYan, HHN=14018807300en_HK
dc.identifier.scopusauthoridMruk, DD=6701823934en_HK
dc.identifier.scopusauthoridLee, WM=24799156600en_HK
dc.identifier.scopusauthoridCheng, CY=7404797787en_HK

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats