File Download
  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Serological protein profiling of neuroblastoma by ProteinChip SELDI-TOF technology

TitleSerological protein profiling of neuroblastoma by ProteinChip SELDI-TOF technology
Authors
KeywordsNeuroblastoma
Tumor biomarkers
Serum markers
Protein profiling
SELDI
Issue Date2005
PublisherJohn Wiley & Sons, Inc. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/35503
Citation
Journal of Cellular Biochemistry, 2005, v. 95 n. 1, p. 165-172 How to Cite?
AbstractSerological proteins of neuroblastoma were profiled and analyzed by ProteinChip-SELDI-TOF MS technology with five types of protein chips. By comparing with normal control, a number of protein or polypeptide signals were found significantly and consistently different in their intensities (expression levels) in tumor sera. Interestingly, nine polypeptide peaks in these proteomic features can be simultaneously detected with consistent variations by more than one type of protein chips. None of the expression differences of these nine polypeptides was found in similar comparisons between healthy controls and hepatomas. Preliminary protein identification showed hints for that some of these proteomic alterations may be closely related to the tumorigenesis of neuroblastoma. These results demonstrated the potential of serological biomarker identification for neuroblastoma by ProteinChip-SELDI technology.
Persistent Identifierhttp://hdl.handle.net/10722/48522
ISSN
2015 Impact Factor: 3.446
2015 SCImago Journal Rankings: 1.520
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorHe, Qen_HK
dc.contributor.authorZhu, Ren_HK
dc.contributor.authorRen, Yen_HK
dc.contributor.authorTam, PKHen_HK
dc.contributor.authorChiu, Jen_HK
dc.date.accessioned2008-05-22T04:16:07Z-
dc.date.available2008-05-22T04:16:07Z-
dc.date.issued2005en_HK
dc.identifier.citationJournal of Cellular Biochemistry, 2005, v. 95 n. 1, p. 165-172en_HK
dc.identifier.issn0730-2312en_HK
dc.identifier.urihttp://hdl.handle.net/10722/48522-
dc.description.abstractSerological proteins of neuroblastoma were profiled and analyzed by ProteinChip-SELDI-TOF MS technology with five types of protein chips. By comparing with normal control, a number of protein or polypeptide signals were found significantly and consistently different in their intensities (expression levels) in tumor sera. Interestingly, nine polypeptide peaks in these proteomic features can be simultaneously detected with consistent variations by more than one type of protein chips. None of the expression differences of these nine polypeptides was found in similar comparisons between healthy controls and hepatomas. Preliminary protein identification showed hints for that some of these proteomic alterations may be closely related to the tumorigenesis of neuroblastoma. These results demonstrated the potential of serological biomarker identification for neuroblastoma by ProteinChip-SELDI technology.en_HK
dc.format.extent275767 bytes-
dc.format.extent254114 bytes-
dc.format.mimetypeapplication/pdf-
dc.format.mimetypeapplication/pdf-
dc.languageengen_HK
dc.publisherJohn Wiley & Sons, Inc. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/35503en_HK
dc.relation.ispartofJournal Of Cellular Biochemistryen_US
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.rightsJournal of Cellular Biochemistry. Copyright © John Wiley & Sons, Inc.en_HK
dc.subjectNeuroblastomaen_HK
dc.subjectTumor biomarkersen_HK
dc.subjectSerum markersen_HK
dc.subjectProtein profilingen_HK
dc.subjectSELDIen_HK
dc.titleSerological protein profiling of neuroblastoma by ProteinChip SELDI-TOF technologyen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0730-2312&volume=95&issue=1&spage=165&epage=172&date=2005&atitle=Serological+protein+profiling+of+neuroblastoma+by+ProteinChip+SELDI-TOF+technologyen_HK
dc.identifier.emailHe, Q: qyhe@hkucc.hku.hken_HK
dc.identifier.emailZhu, R: laurence126@sina.comen_HK
dc.identifier.emailRen, Y: yren@hkucc.hku.hken_HK
dc.identifier.emailTam, PKH: paultam@hkucc.hku.hken_HK
dc.identifier.emailChiu, J: jfchiu@hkucc.hku.hken_HK
dc.identifier.authorityTam, PKH=rp00060en_US
dc.description.naturepostprinten_HK
dc.identifier.doi10.1002/jcb.20417en_HK
dc.identifier.pmid15759280en_HK
dc.identifier.scopuseid_2-s2.0-23844433345en_US
dc.identifier.hkuros97771-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-23844433345&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume95en_US
dc.identifier.issue1en_US
dc.identifier.spage165en_US
dc.identifier.epage172en_US
dc.identifier.isiWOS:000228744000017-

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats