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Article: Proteomics in biomarker discovery and drug development

TitleProteomics in biomarker discovery and drug development
Authors
KeywordsProteomics
Biomarker
Drug discovery
Proteomic application
Issue Date2003
PublisherJohn Wiley & Sons, Inc. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/35503
Citation
Journal of Cellular Biochemistry, 2003, v. 89 n. 5, p. 868-886 How to Cite?
AbstractProteomics is a research field aiming to characterize molecular and cellular dynamics in protein expression and function on a global level. The introduction of proteomics has been greatly broadening our view and accelerating our path in various medical researches. The most significant advantage of proteomics is its ability to examine a whole proteome or sub-proteome in a single experiment so that the protein alterations corresponding to a pathological or biochemical condition at a given time can be considered in an integrated way. Proteomic technology has been extensively used to tackle a wide variety of medical subjects including biomarker discovery and drug development. By complement with other new technique advances in genomics and bioinformatics, proteomics has a great potential to make considerable contribution to biomarker identification and to revolutionize drug development process. This article provides a brief overview of the proteomic technologies and their application in biomarker discovery and drug development.
Persistent Identifierhttp://hdl.handle.net/10722/48516
ISSN
2015 Impact Factor: 3.446
2015 SCImago Journal Rankings: 1.520
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorHe, Qen_HK
dc.contributor.authorChiu, Jen_HK
dc.date.accessioned2008-05-22T04:15:59Z-
dc.date.available2008-05-22T04:15:59Z-
dc.date.issued2003en_HK
dc.identifier.citationJournal of Cellular Biochemistry, 2003, v. 89 n. 5, p. 868-886en_HK
dc.identifier.issn0730-2312en_HK
dc.identifier.urihttp://hdl.handle.net/10722/48516-
dc.description.abstractProteomics is a research field aiming to characterize molecular and cellular dynamics in protein expression and function on a global level. The introduction of proteomics has been greatly broadening our view and accelerating our path in various medical researches. The most significant advantage of proteomics is its ability to examine a whole proteome or sub-proteome in a single experiment so that the protein alterations corresponding to a pathological or biochemical condition at a given time can be considered in an integrated way. Proteomic technology has been extensively used to tackle a wide variety of medical subjects including biomarker discovery and drug development. By complement with other new technique advances in genomics and bioinformatics, proteomics has a great potential to make considerable contribution to biomarker identification and to revolutionize drug development process. This article provides a brief overview of the proteomic technologies and their application in biomarker discovery and drug development.en_HK
dc.format.extent161142 bytes-
dc.format.extent254114 bytes-
dc.format.mimetypeapplication/pdf-
dc.format.mimetypeapplication/pdf-
dc.languageengen_HK
dc.publisherJohn Wiley & Sons, Inc. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/35503en_HK
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.rightsJournal of Cellular Biochemistry. Copyright © John Wiley & Sons, Inc.en_HK
dc.subjectProteomicsen_HK
dc.subjectBiomarkeren_HK
dc.subjectDrug discoveryen_HK
dc.subjectProteomic applicationen_HK
dc.titleProteomics in biomarker discovery and drug developmenten_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0730-2312&volume=89&issue=5&spage=868&epage=886&date=2003&atitle=Proteomics+in+biomarker+discovery+and+drug+developmenten_HK
dc.identifier.emailHe, Q: qyhe@hkucc.hku.hken_HK
dc.identifier.emailChiu, J: jfchiu@hkucc.hku.hken_HK
dc.description.naturepostprinten_HK
dc.identifier.doi10.1002/jcb.10576en_HK
dc.identifier.pmid12874822-
dc.identifier.scopuseid_2-s2.0-0042268086-
dc.identifier.hkuros79294-
dc.identifier.isiWOS:000184554100002-
dc.identifier.citeulike6821367-

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