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Article: Human papillomavirus 16/18 and nasopharyngeal carcinoma

TitleHuman papillomavirus 16/18 and nasopharyngeal carcinoma
Authors
Issue Date1992
PublisherB M J Publishing Group. The Journal's web site is located at http://jcp.bmjjournals.com/
Citation
Journal Of Clinical Pathology, 1992, v. 45 n. 1, p. 81-82 How to Cite?
AbstractSixteen cases of nasopharyngeal carcinoma (eight anaplastic and eight well differentiated squamous types) were examined for the presence of human papillomavirus types 16 and 18 genomes using the polymerase chain reaction on paraffin wax embedded biopsy specimens. Although nasopharyngeal carcinoma, particularly the anaplastic type, is strongly associated with Epstein-Barr virus, other factors may be involved in its pathogenesis. No DNA of either human papillomavirus subtype was detected. It is concluded, therefore, that these two 'high risk' types of human papillomavirus are not implicated in the pathogenesis of nasopharyngeal carcinoma. The number of cases in this series was small, however, and further studies are warranted using fresh biopsy material and including other viral subtypes.
Persistent Identifierhttp://hdl.handle.net/10722/46959
ISSN
2015 Impact Factor: 2.912
2015 SCImago Journal Rankings: 1.260
PubMed Central ID
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorDickens, Pen_HK
dc.contributor.authorSrivastava, Gen_HK
dc.contributor.authorLiu, YTen_HK
dc.date.accessioned2007-10-30T07:02:26Z-
dc.date.available2007-10-30T07:02:26Z-
dc.date.issued1992en_HK
dc.identifier.citationJournal Of Clinical Pathology, 1992, v. 45 n. 1, p. 81-82en_HK
dc.identifier.issn0021-9746en_HK
dc.identifier.urihttp://hdl.handle.net/10722/46959-
dc.description.abstractSixteen cases of nasopharyngeal carcinoma (eight anaplastic and eight well differentiated squamous types) were examined for the presence of human papillomavirus types 16 and 18 genomes using the polymerase chain reaction on paraffin wax embedded biopsy specimens. Although nasopharyngeal carcinoma, particularly the anaplastic type, is strongly associated with Epstein-Barr virus, other factors may be involved in its pathogenesis. No DNA of either human papillomavirus subtype was detected. It is concluded, therefore, that these two 'high risk' types of human papillomavirus are not implicated in the pathogenesis of nasopharyngeal carcinoma. The number of cases in this series was small, however, and further studies are warranted using fresh biopsy material and including other viral subtypes.en_HK
dc.format.extent527965 bytes-
dc.format.extent2697 bytes-
dc.format.mimetypeapplication/pdf-
dc.format.mimetypetext/plain-
dc.languageengen_HK
dc.publisherB M J Publishing Group. The Journal's web site is located at http://jcp.bmjjournals.com/en_HK
dc.relation.ispartofJournal of Clinical Pathologyen_HK
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.rightsJournal of Clinical Pathology. Copyright © B M J Publishing Group.en_HK
dc.subject.meshCarcinoma-microbiologyen_HK
dc.subject.meshCarcinoma,-Squamous-Cell-microbiologyen_HK
dc.subject.meshNasopharyngeal-Neoplasms-microbiologyen_HK
dc.subject.meshPapillomaviridae-isolation-and-purificationen_HK
dc.titleHuman papillomavirus 16/18 and nasopharyngeal carcinomaen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0021-9746&volume=45&issue=1&spage=81&epage=82&date=1992&atitle=Human+papillomavirus+16/18+and+nasopharyngeal+carcinomaen_HK
dc.identifier.emailSrivastava, G:gopesh@pathology.hku.hken_HK
dc.identifier.authoritySrivastava, G=rp00365en_HK
dc.description.naturepublished_or_final_versionen_HK
dc.identifier.pmid1311002-
dc.identifier.pmcidPMC495829-
dc.identifier.scopuseid_2-s2.0-0026555049en_HK
dc.identifier.volume45en_HK
dc.identifier.issue1en_HK
dc.identifier.spage81en_HK
dc.identifier.epage82en_HK
dc.identifier.isiWOS:A1992HA97700022-
dc.publisher.placeUnited Kingdomen_HK

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