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Article: Elevated serum alpha-fetoprotein in a patient with undifferentiated carcinoma of the gall bladder

TitleElevated serum alpha-fetoprotein in a patient with undifferentiated carcinoma of the gall bladder
Authors
Issue Date1995
PublisherB M J Publishing Group. The Journal's web site is located at http://jcp.bmjjournals.com/
Citation
Journal of Clinical Pathology, 1995, v. 48 n. 11, p. 1061-1063 How to Cite?
AbstractAn uncommon case of undifferentiated carcinoma of the gall bladder in a 65 year old Chinese man, who presented with an increased serum alpha-fetoprotein concentration, is reported. Histologically, the tumour had a primitive appearance and was composed of a pavement-like array of poorly differentiated columnar/polygonal cells. Alpha-fetoprotein was demonstrated in some of the tumour cells using an immunoperoxidase technique. Alpha-fetoprotein secretion in this instance may have occurred because the gall bladder and the liver are of similar embryological origin. Alpha-fetoprotein may also be related to the resurgent expression of oncofetal antigens. This tumour may represent another rare cause of increased serum alpha-fetoprotein concentrations.
Persistent Identifierhttp://hdl.handle.net/10722/46955
ISSN
2015 Impact Factor: 2.912
2015 SCImago Journal Rankings: 1.260
PubMed Central ID
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorNg, WKen_HK
dc.contributor.authorNg, WFen_HK
dc.date.accessioned2007-10-30T07:02:21Z-
dc.date.available2007-10-30T07:02:21Z-
dc.date.issued1995en_HK
dc.identifier.citationJournal of Clinical Pathology, 1995, v. 48 n. 11, p. 1061-1063en_HK
dc.identifier.issn0021-9746en_HK
dc.identifier.urihttp://hdl.handle.net/10722/46955-
dc.description.abstractAn uncommon case of undifferentiated carcinoma of the gall bladder in a 65 year old Chinese man, who presented with an increased serum alpha-fetoprotein concentration, is reported. Histologically, the tumour had a primitive appearance and was composed of a pavement-like array of poorly differentiated columnar/polygonal cells. Alpha-fetoprotein was demonstrated in some of the tumour cells using an immunoperoxidase technique. Alpha-fetoprotein secretion in this instance may have occurred because the gall bladder and the liver are of similar embryological origin. Alpha-fetoprotein may also be related to the resurgent expression of oncofetal antigens. This tumour may represent another rare cause of increased serum alpha-fetoprotein concentrations.en_HK
dc.format.extent1147526 bytes-
dc.format.extent1795 bytes-
dc.format.mimetypeapplication/pdf-
dc.format.mimetypetext/plain-
dc.languageengen_HK
dc.publisherB M J Publishing Group. The Journal's web site is located at http://jcp.bmjjournals.com/en_HK
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.rightsJournal of Clinical Pathology. Copyright © B M J Publishing Group.en_HK
dc.subject.meshCarcinoma-blooden_HK
dc.subject.meshGallbladder-Neoplasms-blooden_HK
dc.subject.meshTumor-Markers,-Biological-analysisen_HK
dc.subject.meshalpha-Fetoproteins-analysisen_HK
dc.titleElevated serum alpha-fetoprotein in a patient with undifferentiated carcinoma of the gall bladderen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0021-9746&volume=48&issue=11&spage=1061&epage=1063&date=1995&atitle=Elevated+serum+alpha-fetoprotein+in+a+patient+with+undifferentiated+carcinoma+of+the+gall+bladderen_HK
dc.description.naturepublished_or_final_versionen_HK
dc.identifier.pmid8543634-
dc.identifier.pmcidPMC503017-
dc.identifier.scopuseid_2-s2.0-0028971031-
dc.identifier.isiWOS:A1995TF18200021-

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