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Article: Pattern of symptomatic congenital heart disease amongst Oriental neonates: a decade's experience

TitlePattern of symptomatic congenital heart disease amongst Oriental neonates: a decade's experience
Authors
KeywordsNeonate
Congenital heart disease
Issue Date1996
PublisherCambridge University Press. The Journal's web site is located at http://journals.cambridge.org/action/displayJournal?jid=CTY
Citation
Cardiology in the Young, 1996, v. 6, p. 291-297 How to Cite?
AbstractBetween 1981 and 1990, 765 symptomatic neonates with major congenital heart malformations were admitted into the Grantham Hospital. This represented an incidence of 10 per 10,000 live births for Hong Kong. The figure was comparable to those reported for Caucasians. Among the 744 Oriental neonates, obstruction of the pulmonary outflow tract occurred most frequently (281, 37.8%), followed by left ventricular outflow tract obstruction (169, 22.7%), left-to-right shunting (115, 15.5%), complete transposition (92, 12.4%), common mixing situations (62, 8.3%), and miscellaneous causes (25,3.3%). When compared with the available reports from the West, Chinese neonates had a high preference for pulmonary outflow tract obstruction (p<0.005), especially the anomaly of pulmonary atresia and intact ventricular septum. This correlated well with cyanosis as the commonest neonatal presentation (64%). Contrary to previous reports that aortic coarctation was rare among Orientals, this abnormality was observed frequently in our study. The rare occurrence of critical aortic valvar stenosis among Chinese, however, was supported by our present analysis. Other lesions, such as left-to-right shunting and complete transposition, showed no significant racial difference in the frequency of occurrence. Such knowledge concerning the pattern of congenital heart disease amongst Oriental neonates can facilitate early diagnosis and timely referral of babies to the appropriate center for management.
Persistent Identifierhttp://hdl.handle.net/10722/45223
ISSN
2015 Impact Factor: 0.825
2015 SCImago Journal Rankings: 0.312

 

DC FieldValueLanguage
dc.contributor.authorLeung, MPen_HK
dc.contributor.authorYung, TCen_HK
dc.contributor.authorNg, YKen_HK
dc.contributor.authorWong, KYen_HK
dc.contributor.authorLee, SLen_HK
dc.contributor.authorMok, CKen_HK
dc.contributor.authorLee, Jen_HK
dc.contributor.authorChiu, Cen_HK
dc.date.accessioned2007-10-30T06:20:14Z-
dc.date.available2007-10-30T06:20:14Z-
dc.date.issued1996en_HK
dc.identifier.citationCardiology in the Young, 1996, v. 6, p. 291-297en_HK
dc.identifier.issn1047-9511en_HK
dc.identifier.urihttp://hdl.handle.net/10722/45223-
dc.description.abstractBetween 1981 and 1990, 765 symptomatic neonates with major congenital heart malformations were admitted into the Grantham Hospital. This represented an incidence of 10 per 10,000 live births for Hong Kong. The figure was comparable to those reported for Caucasians. Among the 744 Oriental neonates, obstruction of the pulmonary outflow tract occurred most frequently (281, 37.8%), followed by left ventricular outflow tract obstruction (169, 22.7%), left-to-right shunting (115, 15.5%), complete transposition (92, 12.4%), common mixing situations (62, 8.3%), and miscellaneous causes (25,3.3%). When compared with the available reports from the West, Chinese neonates had a high preference for pulmonary outflow tract obstruction (p<0.005), especially the anomaly of pulmonary atresia and intact ventricular septum. This correlated well with cyanosis as the commonest neonatal presentation (64%). Contrary to previous reports that aortic coarctation was rare among Orientals, this abnormality was observed frequently in our study. The rare occurrence of critical aortic valvar stenosis among Chinese, however, was supported by our present analysis. Other lesions, such as left-to-right shunting and complete transposition, showed no significant racial difference in the frequency of occurrence. Such knowledge concerning the pattern of congenital heart disease amongst Oriental neonates can facilitate early diagnosis and timely referral of babies to the appropriate center for management.en_HK
dc.format.extent1219998 bytes-
dc.format.extent2435 bytes-
dc.format.extent2006 bytes-
dc.format.mimetypeapplication/pdf-
dc.format.mimetypetext/plain-
dc.format.mimetypetext/plain-
dc.languageengen_HK
dc.publisherCambridge University Press. The Journal's web site is located at http://journals.cambridge.org/action/displayJournal?jid=CTYen_HK
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.rightsCardiology in the Young. Copyright © Cambridge University Press.en_HK
dc.subjectNeonateen_HK
dc.subjectCongenital heart diseaseen_HK
dc.titlePattern of symptomatic congenital heart disease amongst Oriental neonates: a decade's experienceen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1047-9511&volume=6&spage=291&epage=297&date=1996&atitle=Pattern+of+symptomatic+congenital+heart+disease+amongst+Oriental+neonates:+a+decade%27s+experienceen_HK
dc.description.naturepublished_or_final_versionen_HK
dc.identifier.scopuseid_2-s2.0-0013100189-
dc.identifier.hkuros24786-

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