File Download
  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Serum lipid and apolipoprotein distributions in Hong Kong Chinese

TitleSerum lipid and apolipoprotein distributions in Hong Kong Chinese
Authors
Issue Date1994
PublisherB M J Publishing Group. The Journal's web site is located at http://jech.bmjjournals.com/
Citation
Journal of Epidemiology & Community Health, 1994, v. 48 n. 4, p. 355-359 How to Cite?
AbstractSTUDY OBJECTIVE--The aim was to describe the distribution of lipids and apolipoproteins in the Chinese population in Hong Kong. DESIGN--This was a prospective, cross sectional, population based survey. SETTINGS--The study was conducted in a single, self referred, out patient screening centre. PARTICIPANTS--Altogether 825 Chinese adults aged > or = 20 years were screened. One hundred subjects who had previously had lipid measurement and 29 who were taking lipid modifying drugs were excluded but 289 men and 407 women remained for further analysis. MAIN RESULTS--Age standardised mean (SEM) lipids concentrations for Hong Kong Chinese were total cholesterol: men, 5.48 (0.05) mmol/l and women, 5.46 (0.06) mmol/l; triglycerides: men, 1.22 (1.03) mmol/l and women, 1.00 (1.03) mmol/l; high density lipoprotein (HDL) cholesterol: men, 1.25 (0.02) mmol/l and women, 1.42 (0.02) mmol/l; low density lipoprotein (LDL) cholesterol: men, 3.56 (0.05) mmol/l and women, 3.50 (0.06) mmol/l; apolipoprotein A-I (apo A-I): men, 1.34 (0.01) g/l and women, 1.46 (0.01) g/l; and apolipoprotein B (apo B): men, 1.15 (0.02) g/l and women, 1.06 (0.02) g/l. The total to HDL cholesterol ratios were men, 4.62 (0.07) and women, 4.10 (0.08); and apo B to apo A-I ratios (apo B/A) were men, 0.88 (0.02) and women, 0.75 (0.02). While levels of total cholesterol, LDL cholesterol, apo B, triglycerides, total/HDL cholesterol, and apo B/A were positively associated with age in both sexes and were higher in men before the age 50-59 years, they rose steeply thereafter in women to cross over the levels in men. In contrast, HDL cholesterol decreased with age while apo A-I remained constant, and both were consistently higher in women than in men in all age groups. CONCLUSIONS--Hong Kong Chinese have attained lipid profiles similar to those in other developed western populations. Environmental factors seem influential in this regard. Faced with the increasing coronary mortality of recent years, there should be a major effort to reduce the cholesterol concentrations in this population.
Persistent Identifierhttp://hdl.handle.net/10722/44975
ISSN
2015 Impact Factor: 3.865
2015 SCImago Journal Rankings: 1.890
PubMed Central ID
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorFong, PCen_HK
dc.contributor.authorTam, SCen_HK
dc.contributor.authorTai, YTen_HK
dc.contributor.authorLau, CPen_HK
dc.contributor.authorLee, Jen_HK
dc.contributor.authorSha, YYen_HK
dc.date.accessioned2007-10-30T06:14:47Z-
dc.date.available2007-10-30T06:14:47Z-
dc.date.issued1994en_HK
dc.identifier.citationJournal of Epidemiology & Community Health, 1994, v. 48 n. 4, p. 355-359en_HK
dc.identifier.issn0143-005Xen_HK
dc.identifier.urihttp://hdl.handle.net/10722/44975-
dc.description.abstractSTUDY OBJECTIVE--The aim was to describe the distribution of lipids and apolipoproteins in the Chinese population in Hong Kong. DESIGN--This was a prospective, cross sectional, population based survey. SETTINGS--The study was conducted in a single, self referred, out patient screening centre. PARTICIPANTS--Altogether 825 Chinese adults aged > or = 20 years were screened. One hundred subjects who had previously had lipid measurement and 29 who were taking lipid modifying drugs were excluded but 289 men and 407 women remained for further analysis. MAIN RESULTS--Age standardised mean (SEM) lipids concentrations for Hong Kong Chinese were total cholesterol: men, 5.48 (0.05) mmol/l and women, 5.46 (0.06) mmol/l; triglycerides: men, 1.22 (1.03) mmol/l and women, 1.00 (1.03) mmol/l; high density lipoprotein (HDL) cholesterol: men, 1.25 (0.02) mmol/l and women, 1.42 (0.02) mmol/l; low density lipoprotein (LDL) cholesterol: men, 3.56 (0.05) mmol/l and women, 3.50 (0.06) mmol/l; apolipoprotein A-I (apo A-I): men, 1.34 (0.01) g/l and women, 1.46 (0.01) g/l; and apolipoprotein B (apo B): men, 1.15 (0.02) g/l and women, 1.06 (0.02) g/l. The total to HDL cholesterol ratios were men, 4.62 (0.07) and women, 4.10 (0.08); and apo B to apo A-I ratios (apo B/A) were men, 0.88 (0.02) and women, 0.75 (0.02). While levels of total cholesterol, LDL cholesterol, apo B, triglycerides, total/HDL cholesterol, and apo B/A were positively associated with age in both sexes and were higher in men before the age 50-59 years, they rose steeply thereafter in women to cross over the levels in men. In contrast, HDL cholesterol decreased with age while apo A-I remained constant, and both were consistently higher in women than in men in all age groups. CONCLUSIONS--Hong Kong Chinese have attained lipid profiles similar to those in other developed western populations. Environmental factors seem influential in this regard. Faced with the increasing coronary mortality of recent years, there should be a major effort to reduce the cholesterol concentrations in this population.en_HK
dc.format.extent1050593 bytes-
dc.format.extent19303 bytes-
dc.format.mimetypeapplication/pdf-
dc.format.mimetypetext/plain-
dc.languageengen_HK
dc.publisherB M J Publishing Group. The Journal's web site is located at http://jech.bmjjournals.com/en_HK
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.rightsJournal of Epidemiology & Community Health. Copyright © B M J Publishing Group.en_HK
dc.subject.meshApolipoproteins-blooden_HK
dc.subject.meshEthnic-Groupsen_HK
dc.subject.meshLipids-blooden_HK
dc.titleSerum lipid and apolipoprotein distributions in Hong Kong Chineseen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0143-005X&volume=48&issue=4&spage=355&epage=359&date=1994&atitle=Serum+lipid+and+apolipoprotein+distributions+in+Hong+Kong+Chineseen_HK
dc.description.naturepublished_or_final_versionen_HK
dc.identifier.pmid7964333-
dc.identifier.pmcidPMC1059983-
dc.identifier.scopuseid_2-s2.0-0027930993-
dc.identifier.isiWOS:A1994PD62900007-

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats