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Article: Early changes of auditory brain stem evoked response after radiotherapy for nasopharyngeal carcinoma - A prospective study

TitleEarly changes of auditory brain stem evoked response after radiotherapy for nasopharyngeal carcinoma - A prospective study
Authors
KeywordsAudiometry, evoked response
Nasopharyngeal neoplasms
Radiotherapy
Issue Date1992
PublisherCambridge University Press. The Journal's web site is located at http://journals.cambridge.org/action/displayJournal?jid=JLO
Citation
Journal Of Laryngology And Otology, 1992, v. 106 n. 10, p. 887-892 How to Cite?
AbstractA prospective study of the effect of radiotherapy for nasopharyngeal carcinoma on hearing was carried out on 49 patients who had pure tone, impedance audiometry and auditory brain stem evoked response (ABR) recordings before, immediately, three, six and 12 months after radiotherapy. Fourteen patients complained of intermittent tinnitus after radiotherapy. We found that 11 initially normal ears of nine patients developed a middle ear effusion, three to six months after radiotherapy. There was mixed sensorineural and conductive hearing impairment after radiotherapy. Persistent impairment of ABR was detected immediately after completion of radiotherapy. The waves I-III and I-V interpeak latency intervals were significantly prolonged one year after radiotherapy. The study shows that radiotherapy for nasopharyngeal carcinoma impairs hearing by acting on the middle ear, the cochlea and the brain stem auditory pathway.
Persistent Identifierhttp://hdl.handle.net/10722/44631
ISSN
2015 Impact Factor: 0.736
2015 SCImago Journal Rankings: 0.447
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorLau, SKen_HK
dc.contributor.authorWei, WLen_HK
dc.contributor.authorSham, JSTen_HK
dc.contributor.authorChoy, DTKen_HK
dc.contributor.authorHui, Yen_HK
dc.date.accessioned2007-10-30T06:06:20Z-
dc.date.available2007-10-30T06:06:20Z-
dc.date.issued1992en_HK
dc.identifier.citationJournal Of Laryngology And Otology, 1992, v. 106 n. 10, p. 887-892en_HK
dc.identifier.issn0022-2151en_HK
dc.identifier.urihttp://hdl.handle.net/10722/44631-
dc.description.abstractA prospective study of the effect of radiotherapy for nasopharyngeal carcinoma on hearing was carried out on 49 patients who had pure tone, impedance audiometry and auditory brain stem evoked response (ABR) recordings before, immediately, three, six and 12 months after radiotherapy. Fourteen patients complained of intermittent tinnitus after radiotherapy. We found that 11 initially normal ears of nine patients developed a middle ear effusion, three to six months after radiotherapy. There was mixed sensorineural and conductive hearing impairment after radiotherapy. Persistent impairment of ABR was detected immediately after completion of radiotherapy. The waves I-III and I-V interpeak latency intervals were significantly prolonged one year after radiotherapy. The study shows that radiotherapy for nasopharyngeal carcinoma impairs hearing by acting on the middle ear, the cochlea and the brain stem auditory pathway.en_HK
dc.format.extent904788 bytes-
dc.format.extent1831689 bytes-
dc.format.extent3031 bytes-
dc.format.extent1832 bytes-
dc.format.mimetypeapplication/pdf-
dc.format.mimetypeapplication/pdf-
dc.format.mimetypetext/plain-
dc.format.mimetypetext/plain-
dc.languageengen_HK
dc.publisherCambridge University Press. The Journal's web site is located at http://journals.cambridge.org/action/displayJournal?jid=JLOen_HK
dc.relation.ispartofJournal of Laryngology and Otologyen_HK
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.rightsJournal of Laryngology and Otology. Copyright © Cambridge University Press.en_HK
dc.subjectAudiometry, evoked responseen_HK
dc.subjectNasopharyngeal neoplasmsen_HK
dc.subjectRadiotherapyen_HK
dc.subject.meshBrain-Stem-radiation-effectsen_HK
dc.subject.meshEvoked-Potentials,-Auditory,-Brain-Stem-radiation-effectsen_HK
dc.subject.meshNasopharyngeal-Neoplasms-radiotherapyen_HK
dc.titleEarly changes of auditory brain stem evoked response after radiotherapy for nasopharyngeal carcinoma - A prospective studyen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0022-2151&volume=106&issue=10&spage=887&epage=892&date=1992&atitle=Early+changes+of+auditory+brain+stem+evoked+response+after+radiotherapy+for+nasopharyngeal+carcinoma:+a+prospective+studyen_HK
dc.identifier.emailWei, WL: hrmswwi@hku.hken_HK
dc.identifier.authorityWei, WL=rp00323en_HK
dc.description.naturepublished_or_final_versionen_HK
dc.identifier.pmid1474310-
dc.identifier.scopuseid_2-s2.0-0026483882en_HK
dc.identifier.volume106en_HK
dc.identifier.issue10en_HK
dc.identifier.spage887en_HK
dc.identifier.epage892en_HK
dc.identifier.isiWOS:A1992JZ20000005-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridLau, SK=25932968400en_HK
dc.identifier.scopusauthoridWei, WL=7403321552en_HK
dc.identifier.scopusauthoridSham, JST=24472255400en_HK
dc.identifier.scopusauthoridChoy, DTK=7102939127en_HK
dc.identifier.scopusauthoridHui, Y=7103107552en_HK

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