File Download
  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Nasopharyngeal carcinoma in situ in nasopharyngeal carcinoma

TitleNasopharyngeal carcinoma in situ in nasopharyngeal carcinoma
Authors
Issue Date1992
PublisherB M J Publishing Group. The Journal's web site is located at http://jcp.bmjjournals.com/
Citation
Journal Of Clinical Pathology, 1992, v. 45 n. 10, p. 898-901 How to Cite?
AbstractAims: To assess the presence of carcinoma in situ (CIS) in patients with nasopharyngeal carcinoma (NPC) and to see if the number of biopsy sites facilitates detection of CIS. Methods: Formalin fixed, parafin wax embedded biopsy specimens (n = 285) from 187 patients with NPC in 1987 were studied for the presence of CIS as well as for the histological assessment of the subtype of CIS. Results: Fifteen (8.0%) patients had CIS, representing 8.3% of all new patients with NPC and 11.6% of patients with persistent disease or relapse. CIS was undifferentiated or poorly differentiated, no cases of well differentiated squamous cell CIS were identified. There was no significant difference in the incidence of CIS when multiple endoscopic biopsy specimens were taken rather than single forceps biopsy specimens. Conclusions: CIS can only be identified in a few patients with NPC largely because of late presentation with advanced disease at the time of diagnosis and the focal nature of the dysplastic process. The presence of dysplasia in relapses of NPC suggests that these tumours may be second growths rather than regrowths of a primary tumour.
Persistent Identifierhttp://hdl.handle.net/10722/44630
ISSN
2015 Impact Factor: 2.912
2015 SCImago Journal Rankings: 1.260
PubMed Central ID
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorChan, CWen_HK
dc.contributor.authorNicholls, JMen_HK
dc.contributor.authorSham, JSTen_HK
dc.contributor.authorDickens, Pen_HK
dc.contributor.authorChoy, Den_HK
dc.date.accessioned2007-10-30T06:06:17Z-
dc.date.available2007-10-30T06:06:17Z-
dc.date.issued1992en_HK
dc.identifier.citationJournal Of Clinical Pathology, 1992, v. 45 n. 10, p. 898-901en_HK
dc.identifier.issn0021-9746en_HK
dc.identifier.urihttp://hdl.handle.net/10722/44630-
dc.description.abstractAims: To assess the presence of carcinoma in situ (CIS) in patients with nasopharyngeal carcinoma (NPC) and to see if the number of biopsy sites facilitates detection of CIS. Methods: Formalin fixed, parafin wax embedded biopsy specimens (n = 285) from 187 patients with NPC in 1987 were studied for the presence of CIS as well as for the histological assessment of the subtype of CIS. Results: Fifteen (8.0%) patients had CIS, representing 8.3% of all new patients with NPC and 11.6% of patients with persistent disease or relapse. CIS was undifferentiated or poorly differentiated, no cases of well differentiated squamous cell CIS were identified. There was no significant difference in the incidence of CIS when multiple endoscopic biopsy specimens were taken rather than single forceps biopsy specimens. Conclusions: CIS can only be identified in a few patients with NPC largely because of late presentation with advanced disease at the time of diagnosis and the focal nature of the dysplastic process. The presence of dysplasia in relapses of NPC suggests that these tumours may be second growths rather than regrowths of a primary tumour.en_HK
dc.format.extent1953739 bytes-
dc.format.extent1761 bytes-
dc.format.mimetypeapplication/pdf-
dc.format.mimetypetext/plain-
dc.languageengen_HK
dc.publisherB M J Publishing Group. The Journal's web site is located at http://jcp.bmjjournals.com/en_HK
dc.relation.ispartofJournal of Clinical Pathologyen_HK
dc.rightsJournal of Clinical Pathology. Copyright © B M J Publishing Group.en_HK
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.subject.meshCarcinoma-in-Situ-pathologyen_HK
dc.subject.meshNasopharyngeal-Neoplasms-pathologyen_HK
dc.titleNasopharyngeal carcinoma in situ in nasopharyngeal carcinomaen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0021-9746&volume=45&issue=10&spage=898&epage=901&date=1992&atitle=Nasopharyngeal+carcinoma+in+situ+in+nasopharyngeal+carcinomaen_HK
dc.identifier.emailNicholls, JM:nicholls@pathology.hku.hken_HK
dc.identifier.authorityNicholls, JM=rp00364en_HK
dc.description.naturepublished_or_final_versionen_HK
dc.identifier.pmid1430260-
dc.identifier.pmcidPMC495062-
dc.identifier.scopuseid_2-s2.0-0026440534en_HK
dc.identifier.volume45en_HK
dc.identifier.issue10en_HK
dc.identifier.spage898en_HK
dc.identifier.epage901en_HK
dc.identifier.isiWOS:A1992JT47300012-
dc.publisher.placeUnited Kingdomen_HK

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats