File Download
  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Human chromosome 7: DNA sequence and biology

TitleHuman chromosome 7: DNA sequence and biology
Authors
Issue Date2003
PublisherAmerican Association for the Advancement of Science. The Journal's web site is located at http://sciencemag.org
Citation
Science, 2003, v. 300 n. 5620, p. 767-772 How to Cite?
Abstract
DNA sequence and annotation of the entire human chromosome 7, encompassing nearly 158 million nucleotides of DNA and 1917 gene structures, are presented. To generate a higher order description, additional structural features such as imprinted genes, fragile sites, and segmental duplications were integrated at the level of the DNA sequence with medical genetic data, including 440 chromosome rearrangement breakpoints associated with disease. This approach enabled the discovery of candidate genes for developmental diseases including autism.
Persistent Identifierhttp://hdl.handle.net/10722/44382
ISSN
2013 Impact Factor: 31.477
2013 SCImago Journal Rankings: 12.465
PubMed Central ID
ISI Accession Number ID
References

 

Author Affiliations
  1. Baylor College of Medicine
  2. Memorial University of Newfoundland, Faculty of Medicine
  3. Massachusetts General Hospital
  4. Karolinska University Hospital
  5. Alfred I. duPont Hospital for Children
  6. McMaster University
  7. The Children's Hospital of Philadelphia
  8. Celera Rockville
  9. The University of Hong Kong
  10. Università degli Studi di Roma Tor Vergata
  11. Centro de Regulacion Genomica
  12. University of Phoenix
  13. Harvard Medical School
  14. University Health Network University of Toronto
  15. University of Wisconsin Madison
  16. Section of Cancer Genetics
  17. Karl-Franzens-Universitat Graz
  18. Wayne State University School of Medicine
  19. Universität Marburg
  20. Fondazione IFOM Istituto Firc di Oncologia Molecolare
  21. Imperial College London
  22. University of Victoria
  23. Yale University School of Medicine
  24. The University of British Columbia
  25. Universitätsklinikum Ulm
  26. John Radcliffe Hospital
  27. Istituto Europeo di Oncologia
  28. Hebrew University of Jerusalem
  29. University of Toronto
  30. Royal Bournemouth Hospital
  31. Brigham and Women's Hospital
  32. North York General Hospital
  33. Hospital for Sick Children University of Toronto
  34. Children's Hospital Boston
DC FieldValueLanguage
dc.contributor.authorScherer, SWen_HK
dc.contributor.authorCheung, Jen_HK
dc.contributor.authorMacDonald, JRen_HK
dc.contributor.authorOsborne, LRen_HK
dc.contributor.authorNakabayashi, Ken_HK
dc.contributor.authorHerbrick, JAen_HK
dc.contributor.authorCarson, ARen_HK
dc.contributor.authorParkerKatiraee, Len_HK
dc.contributor.authorSkaug, Jen_HK
dc.contributor.authorKhaja, Ren_HK
dc.contributor.authorZhang, Jen_HK
dc.contributor.authorHudek, AKen_HK
dc.contributor.authorLi, Men_HK
dc.contributor.authorHaddad, Men_HK
dc.contributor.authorDuggan, GEen_HK
dc.contributor.authorFernandez, BAen_HK
dc.contributor.authorKanematsu, Een_HK
dc.contributor.authorGentles, Sen_HK
dc.contributor.authorChristopoulos, CCen_HK
dc.contributor.authorChoufani, Sen_HK
dc.contributor.authorKwasnicka, Den_HK
dc.contributor.authorZheng, XHen_HK
dc.contributor.authorLai, Zen_HK
dc.contributor.authorNusskern, Den_HK
dc.contributor.authorZhang, Qen_HK
dc.contributor.authorGu, Zen_HK
dc.contributor.authorLu, Fen_HK
dc.contributor.authorZeesman, Sen_HK
dc.contributor.authorNowaczyk, MJen_HK
dc.contributor.authorTeshima, Ien_HK
dc.contributor.authorChitayat, Den_HK
dc.contributor.authorShuman, Cen_HK
dc.contributor.authorWeksberg, Ren_HK
dc.contributor.authorZackai, EHen_HK
dc.contributor.authorGrebe, TAen_HK
dc.contributor.authorCox, SRen_HK
dc.contributor.authorKirkpatrick, SJen_HK
dc.contributor.authorRahman, Nen_HK
dc.contributor.authorFriedman, JMen_HK
dc.contributor.authorHeng, HHQen_HK
dc.contributor.authorPelicci, PGen_HK
dc.contributor.authorLoCoco, Fen_HK
dc.contributor.authorBelloni, Een_HK
dc.contributor.authorShaffer, LGen_HK
dc.contributor.authorPober, Ben_HK
dc.contributor.authorMorton, CCen_HK
dc.contributor.authorGusella, JFen_HK
dc.contributor.authorBruns, GAPen_HK
dc.contributor.authorKorf, BRen_HK
dc.contributor.authorQuade, BJen_HK
dc.contributor.authorLigon, AHen_HK
dc.contributor.authorFerguson, Hen_HK
dc.contributor.authorHiggins, AWen_HK
dc.contributor.authorLeach, NTen_HK
dc.contributor.authorHerrick, SRen_HK
dc.contributor.authorLemyre, Een_HK
dc.contributor.authorFarra, CGen_HK
dc.contributor.authorKim, HGen_HK
dc.contributor.authorSummers, AMen_HK
dc.contributor.authorGripp, KWen_HK
dc.contributor.authorRoberts, Wen_HK
dc.contributor.authorSzatmari, Pen_HK
dc.contributor.authorWinsor, EJTen_HK
dc.contributor.authorGrzeschik, KHen_HK
dc.contributor.authorTeebi, Aen_HK
dc.contributor.authorMinassian, BAen_HK
dc.contributor.authorKere, Jen_HK
dc.contributor.authorArmengol, Len_HK
dc.contributor.authorPujana, MAen_HK
dc.contributor.authorEstivill, Xen_HK
dc.contributor.authorWilson, MDen_HK
dc.contributor.authorKoop, BFen_HK
dc.contributor.authorTosi, Sen_HK
dc.contributor.authorMoore, GEen_HK
dc.contributor.authorBoright, APen_HK
dc.contributor.authorZlotorynski, Een_HK
dc.contributor.authorKerem, Ben_HK
dc.contributor.authorKroisel, PMen_HK
dc.contributor.authorPetek, Een_HK
dc.contributor.authorOscier, DGen_HK
dc.contributor.authorMould, SJen_HK
dc.contributor.authorDöhner, Hen_HK
dc.contributor.authorDöhner, Ken_HK
dc.contributor.authorRommens, JMen_HK
dc.contributor.authorVincent, JBen_HK
dc.contributor.authorVenter, JCen_HK
dc.contributor.authorLi, PWen_HK
dc.contributor.authorMural, RJen_HK
dc.contributor.authorAdams, MDen_HK
dc.contributor.authorTsui, LCen_HK
dc.date.accessioned2007-09-12T03:52:27Z-
dc.date.available2007-09-12T03:52:27Z-
dc.date.issued2003en_HK
dc.identifier.citationScience, 2003, v. 300 n. 5620, p. 767-772en_HK
dc.identifier.issn0036-8075en_HK
dc.identifier.urihttp://hdl.handle.net/10722/44382-
dc.description.abstractDNA sequence and annotation of the entire human chromosome 7, encompassing nearly 158 million nucleotides of DNA and 1917 gene structures, are presented. To generate a higher order description, additional structural features such as imprinted genes, fragile sites, and segmental duplications were integrated at the level of the DNA sequence with medical genetic data, including 440 chromosome rearrangement breakpoints associated with disease. This approach enabled the discovery of candidate genes for developmental diseases including autism.en_HK
dc.languageengen_HK
dc.publisherAmerican Association for the Advancement of Science. The Journal's web site is located at http://sciencemag.orgen_HK
dc.relation.ispartofScienceen_HK
dc.rightsScience. Copyright © American Association for the Advancement of Science.en_HK
dc.subject.meshChromosomes, human, pair 7 - geneticsen_HK
dc.subject.meshSequence analysis, dnaen_HK
dc.subject.meshGenetic diseases, inborn - geneticsen_HK
dc.subject.meshDna, complementaryen_HK
dc.subject.meshExpressed sequence tagsen_HK
dc.titleHuman chromosome 7: DNA sequence and biologyen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0036-8075&volume=300&issue=5620&spage=767&epage=772&date=2003&atitle=Human+Chromosome+7:+DNA+sequence+and+biologyen_HK
dc.identifier.emailTsui, LC: tsuilc@hkucc.hku.hken_HK
dc.identifier.authorityTsui, LC=rp00058en_HK
dc.description.naturelink_to_OA_fulltexten_HK
dc.identifier.doi10.1126/science.1083423en_HK
dc.identifier.pmid12690205en_HK
dc.identifier.pmcidPMC2882961-
dc.identifier.scopuseid_2-s2.0-0038756128en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0038756128&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume300en_HK
dc.identifier.issue5620en_HK
dc.identifier.spage767en_HK
dc.identifier.epage772en_HK
dc.identifier.isiWOS:000182579800041-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridScherer, SW=35374654500en_HK
dc.identifier.scopusauthoridCheung, J=7202072292en_HK
dc.identifier.scopusauthoridMacDonald, JR=7401439417en_HK
dc.identifier.scopusauthoridOsborne, LR=35369973100en_HK
dc.identifier.scopusauthoridNakabayashi, K=7101927819en_HK
dc.identifier.scopusauthoridHerbrick, JA=6602297751en_HK
dc.identifier.scopusauthoridCarson, AR=7004283094en_HK
dc.identifier.scopusauthoridParkerKatiraee, L=6505916235en_HK
dc.identifier.scopusauthoridSkaug, J=6603258009en_HK
dc.identifier.scopusauthoridKhaja, R=7801610375en_HK
dc.identifier.scopusauthoridZhang, J=8590381800en_HK
dc.identifier.scopusauthoridHudek, AK=6507434827en_HK
dc.identifier.scopusauthoridLi, M=7405264026en_HK
dc.identifier.scopusauthoridHaddad, M=36729003200en_HK
dc.identifier.scopusauthoridDuggan, GE=55209364400en_HK
dc.identifier.scopusauthoridFernandez, BA=7201505098en_HK
dc.identifier.scopusauthoridKanematsu, E=6603868463en_HK
dc.identifier.scopusauthoridGentles, S=6602913308en_HK
dc.identifier.scopusauthoridChristopoulos, CC=7101816982en_HK
dc.identifier.scopusauthoridChoufani, S=6602384937en_HK
dc.identifier.scopusauthoridKwasnicka, D=6506812634en_HK
dc.identifier.scopusauthoridZheng, XH=7404090698en_HK
dc.identifier.scopusauthoridLai, Z=7102721701en_HK
dc.identifier.scopusauthoridNusskern, D=6602890230en_HK
dc.identifier.scopusauthoridZhang, Q=7407966512en_HK
dc.identifier.scopusauthoridGu, Z=7401760227en_HK
dc.identifier.scopusauthoridLu, F=36892768100en_HK
dc.identifier.scopusauthoridZeesman, S=6602585451en_HK
dc.identifier.scopusauthoridNowaczyk, MJ=7006802352en_HK
dc.identifier.scopusauthoridTeshima, I=7003305081en_HK
dc.identifier.scopusauthoridChitayat, D=7005750871en_HK
dc.identifier.scopusauthoridShuman, C=7006406663en_HK
dc.identifier.scopusauthoridWeksberg, R=7006112330en_HK
dc.identifier.scopusauthoridZackai, EH=35379162500en_HK
dc.identifier.scopusauthoridGrebe, TA=7004670178en_HK
dc.identifier.scopusauthoridCox, SR=7401455988en_HK
dc.identifier.scopusauthoridKirkpatrick, SJ=7102717405en_HK
dc.identifier.scopusauthoridRahman, N=7101749310en_HK
dc.identifier.scopusauthoridFriedman, JM=7401865845en_HK
dc.identifier.scopusauthoridHeng, HHQ=7005338076en_HK
dc.identifier.scopusauthoridPelicci, PG=35379722300en_HK
dc.identifier.scopusauthoridLoCoco, F=22135403000en_HK
dc.identifier.scopusauthoridBelloni, E=7003332359en_HK
dc.identifier.scopusauthoridShaffer, LG=7103378971en_HK
dc.identifier.scopusauthoridPober, B=7003518920en_HK
dc.identifier.scopusauthoridMorton, CC=7201605341en_HK
dc.identifier.scopusauthoridGusella, JF=36065462700en_HK
dc.identifier.scopusauthoridBruns, GAP=7006562251en_HK
dc.identifier.scopusauthoridKorf, BR=7006449779en_HK
dc.identifier.scopusauthoridQuade, BJ=7003445915en_HK
dc.identifier.scopusauthoridLigon, AH=6603938198en_HK
dc.identifier.scopusauthoridFerguson, H=23984662800en_HK
dc.identifier.scopusauthoridHiggins, AW=7102775648en_HK
dc.identifier.scopusauthoridLeach, NT=6701636722en_HK
dc.identifier.scopusauthoridHerrick, SR=7003721947en_HK
dc.identifier.scopusauthoridLemyre, E=26642879200en_HK
dc.identifier.scopusauthoridFarra, CG=6602363423en_HK
dc.identifier.scopusauthoridKim, HG=7410138468en_HK
dc.identifier.scopusauthoridSummers, AM=7103024535en_HK
dc.identifier.scopusauthoridGripp, KW=7003437387en_HK
dc.identifier.scopusauthoridRoberts, W=7403316556en_HK
dc.identifier.scopusauthoridSzatmari, P=7006673362en_HK
dc.identifier.scopusauthoridWinsor, EJT=7004223177en_HK
dc.identifier.scopusauthoridGrzeschik, KH=7004321252en_HK
dc.identifier.scopusauthoridTeebi, A=7004661664en_HK
dc.identifier.scopusauthoridMinassian, BA=7004098060en_HK
dc.identifier.scopusauthoridKere, J=7005922099en_HK
dc.identifier.scopusauthoridArmengol, L=6602900598en_HK
dc.identifier.scopusauthoridPujana, MA=6602567669en_HK
dc.identifier.scopusauthoridEstivill, X=36047834200en_HK
dc.identifier.scopusauthoridWilson, MD=7408666439en_HK
dc.identifier.scopusauthoridKoop, BF=7006161280en_HK
dc.identifier.scopusauthoridTosi, S=24286990900en_HK
dc.identifier.scopusauthoridMoore, GE=7403283500en_HK
dc.identifier.scopusauthoridBoright, AP=6603298498en_HK
dc.identifier.scopusauthoridZlotorynski, E=9239027300en_HK
dc.identifier.scopusauthoridKerem, B=35376353800en_HK
dc.identifier.scopusauthoridKroisel, PM=7004226032en_HK
dc.identifier.scopusauthoridPetek, E=7004484674en_HK
dc.identifier.scopusauthoridOscier, DG=7005408586en_HK
dc.identifier.scopusauthoridMould, SJ=6603176921en_HK
dc.identifier.scopusauthoridDöhner, H=35374055900en_HK
dc.identifier.scopusauthoridDöhner, K=6701684371en_HK
dc.identifier.scopusauthoridRommens, JM=7006884140en_HK
dc.identifier.scopusauthoridVincent, JB=55421640400en_HK
dc.identifier.scopusauthoridVenter, JC=35352327000en_HK
dc.identifier.scopusauthoridLi, PW=7404773444en_HK
dc.identifier.scopusauthoridMural, RJ=7003349003en_HK
dc.identifier.scopusauthoridAdams, MD=7403905579en_HK
dc.identifier.scopusauthoridTsui, LC=7102754167en_HK

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats