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Article: Cloning and chromosomal mapping of three novel genes, GPR9, GPR10, and GPR14, encoding receptors related to interleukin 8, neuropeptide Y, and somatostatin receptors

TitleCloning and chromosomal mapping of three novel genes, GPR9, GPR10, and GPR14, encoding receptors related to interleukin 8, neuropeptide Y, and somatostatin receptors
Authors
Issue Date1995
PublisherAcademic Press. The Journal's web site is located at http://www.elsevier.com/locate/ygeno
Citation
Genomics, 1995, v. 29 n. 2, p. 335-344 How to Cite?
AbstractWe employed the polymerase chain reaction and genomic DNA library screening to clone novel human genes, GPR9 and GPR10, and a rat gene, GPR14. GPR9, GPR10, and GPR14 each encode G protein-coupled receptors. GPR10 and GPR14 are intronless within their coding regions, while GPR9 contains at least one intron. The receptor encoded by GPR9 shares the highest identity with human IL-8 receptor type B (38% overall and 53% in the transmembrane regions), followed by IL-8 receptor type A (36% overall and 51% in the transmembrane domains). GPR10 encodes a receptor that shares highest identity with the neuropeptide Y receptor (31% overall and 46% in the transmembrane domains). The receptor encoded by GPR14 shares highest identity with the somatostatin receptor SSTR 4 (27% overall and 41% in the transmembrane domains). Fluorescence in situ hybridization analysis localized GPR9 to chromosome 8p11.2-p12 and GPR10 to chromosome 10q25.3-q26.
Persistent Identifierhttp://hdl.handle.net/10722/44289
ISSN
2015 Impact Factor: 2.386
2015 SCImago Journal Rankings: 1.281
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorMarchese, Aen_HK
dc.contributor.authorHeiber, Men_HK
dc.contributor.authorNguyen, Ten_HK
dc.contributor.authorHeng, HHQen_HK
dc.contributor.authorSaldivia, VRen_HK
dc.contributor.authorCheng, Ren_HK
dc.contributor.authorMurphy, PMen_HK
dc.contributor.authorTsui, LCen_HK
dc.contributor.authorShi, Xen_HK
dc.contributor.authorGregor, Pen_HK
dc.contributor.authorGeorge, SRen_HK
dc.contributor.authorO'Dowd, BFen_HK
dc.contributor.authorDocherty, JMen_HK
dc.date.accessioned2007-09-12T03:50:43Z-
dc.date.available2007-09-12T03:50:43Z-
dc.date.issued1995en_HK
dc.identifier.citationGenomics, 1995, v. 29 n. 2, p. 335-344en_HK
dc.identifier.issn0888-7543en_HK
dc.identifier.urihttp://hdl.handle.net/10722/44289-
dc.description.abstractWe employed the polymerase chain reaction and genomic DNA library screening to clone novel human genes, GPR9 and GPR10, and a rat gene, GPR14. GPR9, GPR10, and GPR14 each encode G protein-coupled receptors. GPR10 and GPR14 are intronless within their coding regions, while GPR9 contains at least one intron. The receptor encoded by GPR9 shares the highest identity with human IL-8 receptor type B (38% overall and 53% in the transmembrane regions), followed by IL-8 receptor type A (36% overall and 51% in the transmembrane domains). GPR10 encodes a receptor that shares highest identity with the neuropeptide Y receptor (31% overall and 46% in the transmembrane domains). The receptor encoded by GPR14 shares highest identity with the somatostatin receptor SSTR 4 (27% overall and 41% in the transmembrane domains). Fluorescence in situ hybridization analysis localized GPR9 to chromosome 8p11.2-p12 and GPR10 to chromosome 10q25.3-q26.en_HK
dc.languageengen_HK
dc.publisherAcademic Press. The Journal's web site is located at http://www.elsevier.com/locate/ygenoen_HK
dc.relation.ispartofGenomicsen_HK
dc.subject.meshAntigens, cd - biosynthesis - chemistry - geneticsen_HK
dc.subject.meshInterleukin-8 - metabolismen_HK
dc.subject.meshLymphocytes - cytology - immunology - metabolismen_HK
dc.subject.meshRna, messenger - isolation & purification - metabolismen_HK
dc.subject.meshReceptors, interleukin - biosynthesis - chemistry - geneticsen_HK
dc.titleCloning and chromosomal mapping of three novel genes, GPR9, GPR10, and GPR14, encoding receptors related to interleukin 8, neuropeptide Y, and somatostatin receptorsen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0888-7543&volume=29&issue=2&spage=335&epage=344&date=1995&atitle=Cloning+and+chromosomal+mapping+of+three+novel+genes,+GPR9,+GPR10,+and+GPR14,+encoding+receptors+related+to+interleukin+8,+neuropeptide+Y,+and+somatostatin+receptorsen_HK
dc.identifier.emailTsui, LC: tsuilc@hkucc.hku.hken_HK
dc.identifier.authorityTsui, LC=rp00058en_HK
dc.description.naturelink_to_subscribed_fulltexten_HK
dc.identifier.doi10.1006/geno.1995.9996en_HK
dc.identifier.pmid8666380-
dc.identifier.scopuseid_2-s2.0-0029102720en_HK
dc.identifier.volume29en_HK
dc.identifier.issue2en_HK
dc.identifier.spage335en_HK
dc.identifier.epage344en_HK
dc.identifier.isiWOS:A1995RY05500004-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridMarchese, A=7005075855en_HK
dc.identifier.scopusauthoridHeiber, M=6507950665en_HK
dc.identifier.scopusauthoridNguyen, T=26667936100en_HK
dc.identifier.scopusauthoridHeng, HHQ=7005338076en_HK
dc.identifier.scopusauthoridSaldivia, VR=6602144935en_HK
dc.identifier.scopusauthoridCheng, R=7201955297en_HK
dc.identifier.scopusauthoridMurphy, PM=7401685174en_HK
dc.identifier.scopusauthoridTsui, LC=7102754167en_HK
dc.identifier.scopusauthoridShi, X=7402953863en_HK
dc.identifier.scopusauthoridGregor, P=7005077731en_HK
dc.identifier.scopusauthoridGeorge, SR=35429392100en_HK
dc.identifier.scopusauthoridO'Dowd, BF=7102778005en_HK
dc.identifier.scopusauthoridDocherty, JM=7102949746en_HK

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