File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Article: The murine Xe169 gene escapes X-inactivation like its human homologue

TitleThe murine Xe169 gene escapes X-inactivation like its human homologue
Authors
Issue Date1994
PublisherNature Publishing Group. The Journal's web site is located at http://www.genetics.nature.com
Citation
Nature Genetics, 1994, v. 7 n. 4, p. 491-496 How to Cite?
AbstractAmong a number of genes that escape X-chromosome inactivation in humans, three have been evaluated in mice and unexpectedly all three are subject to X-inactivation. We report here the cloning and expression studies of a novel mouse gene, Xe169, and show that it escapes X-inactivation like its human homologue. Xe169 was assigned to band F2/F3 on the mouse X chromosome by fluorescent in situ hybridization and Southern analysis indicates that the gene is located outside the pseudoautosomal region. Homologous, but divergent, sequences exist on the Y chromosome. In vitro and in vivo studies show that Xe169 is expressed from both the active and the inactive X chromosomes. Xe169 is the first cloned non-pseudoautosomal gene that escapes X-inactivation in mice.
Persistent Identifierhttp://hdl.handle.net/10722/44276
ISSN
2015 Impact Factor: 31.616
2015 SCImago Journal Rankings: 23.762
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorWu, Jen_HK
dc.contributor.authorSalido, ECen_HK
dc.contributor.authorYen, PHen_HK
dc.contributor.authorMohandas, TKen_HK
dc.contributor.authorHeng, HHQen_HK
dc.contributor.authorTsui, LCen_HK
dc.contributor.authorPark, Jen_HK
dc.contributor.authorChapman, VMen_HK
dc.contributor.authorShapiro, LJen_HK
dc.date.accessioned2007-09-12T03:50:27Z-
dc.date.available2007-09-12T03:50:27Z-
dc.date.issued1994en_HK
dc.identifier.citationNature Genetics, 1994, v. 7 n. 4, p. 491-496en_HK
dc.identifier.issn1061-4036en_HK
dc.identifier.urihttp://hdl.handle.net/10722/44276-
dc.description.abstractAmong a number of genes that escape X-chromosome inactivation in humans, three have been evaluated in mice and unexpectedly all three are subject to X-inactivation. We report here the cloning and expression studies of a novel mouse gene, Xe169, and show that it escapes X-inactivation like its human homologue. Xe169 was assigned to band F2/F3 on the mouse X chromosome by fluorescent in situ hybridization and Southern analysis indicates that the gene is located outside the pseudoautosomal region. Homologous, but divergent, sequences exist on the Y chromosome. In vitro and in vivo studies show that Xe169 is expressed from both the active and the inactive X chromosomes. Xe169 is the first cloned non-pseudoautosomal gene that escapes X-inactivation in mice.en_HK
dc.languageengen_HK
dc.publisherNature Publishing Group. The Journal's web site is located at http://www.genetics.nature.comen_HK
dc.relation.ispartofNature Geneticsen_HK
dc.subject.meshDna, complementary - geneticsen_HK
dc.subject.meshDosage compensation, geneticen_HK
dc.subject.meshIn situ hybridization, fluorescenceen_HK
dc.subject.meshX chromosomeen_HK
dc.subject.meshMuridaeen_HK
dc.titleThe murine Xe169 gene escapes X-inactivation like its human homologueen_HK
dc.typeArticleen_HK
dc.identifier.emailTsui, LC: tsuilc@hkucc.hku.hken_HK
dc.identifier.authorityTsui, LC=rp00058en_HK
dc.description.naturelink_to_subscribed_fulltexten_HK
dc.identifier.doi10.1038/ng0894-491en_HK
dc.identifier.pmid7951318-
dc.identifier.scopuseid_2-s2.0-0028145743en_HK
dc.identifier.volume7en_HK
dc.identifier.issue4en_HK
dc.identifier.spage491en_HK
dc.identifier.epage496en_HK
dc.identifier.isiWOS:A1994PA83200015-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridWu, J=16074540400en_HK
dc.identifier.scopusauthoridSalido, EC=14023538500en_HK
dc.identifier.scopusauthoridYen, PH=7201991091en_HK
dc.identifier.scopusauthoridMohandas, TK=16454487200en_HK
dc.identifier.scopusauthoridHeng, HHQ=7005338076en_HK
dc.identifier.scopusauthoridTsui, LC=7102754167en_HK
dc.identifier.scopusauthoridPark, J=15036449300en_HK
dc.identifier.scopusauthoridChapman, VM=7101726745en_HK
dc.identifier.scopusauthoridShapiro, LJ=7402091340en_HK

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats