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Article: Chromosomal localization of the human gene encoding the 51-kDa subunit of mitochondrial complex I (NDUFV1) to 11q13

TitleChromosomal localization of the human gene encoding the 51-kDa subunit of mitochondrial complex I (NDUFV1) to 11q13
Authors
Issue Date1993
PublisherAcademic Press. The Journal's web site is located at http://www.elsevier.com/locate/ygeno
Citation
Genomics, 1993, v. 18 n. 2, p. 435-439 How to Cite?
AbstractThe 51-kDa flavoprotein subunit of mitochondrial NADH:ubiquinone oxidoreductase (Complex I) [NADH dehydrogenase (ubiquinone), flavoprotein 1 (51 kDa); EC 1.6.5.3] plays an important role in the formation of the NADH-binding site and is believed to be the principal site of entry for electrons donated by NADH into the respiratory chain. Human cDNA fragments of the 51-kDa protein were generated by polymerase chain reaction and used to localize the gene (NDUFV1) for this subunit to 11q13 by two separate techniques. This region of the human genome is strongly implicated in a number of different forms of cancer.
Persistent Identifierhttp://hdl.handle.net/10722/44268
ISSN
2015 Impact Factor: 2.386
2015 SCImago Journal Rankings: 1.281
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorAli, STen_HK
dc.contributor.authorDuncan, AMVen_HK
dc.contributor.authorSchappert, Ken_HK
dc.contributor.authorHeng, HHQen_HK
dc.contributor.authorTsui, L-Cen_HK
dc.contributor.authorChow, Wen_HK
dc.contributor.authorRobinson, BHen_HK
dc.date.accessioned2007-09-12T03:50:17Z-
dc.date.available2007-09-12T03:50:17Z-
dc.date.issued1993en_HK
dc.identifier.citationGenomics, 1993, v. 18 n. 2, p. 435-439en_HK
dc.identifier.issn0888-7543en_HK
dc.identifier.urihttp://hdl.handle.net/10722/44268-
dc.description.abstractThe 51-kDa flavoprotein subunit of mitochondrial NADH:ubiquinone oxidoreductase (Complex I) [NADH dehydrogenase (ubiquinone), flavoprotein 1 (51 kDa); EC 1.6.5.3] plays an important role in the formation of the NADH-binding site and is believed to be the principal site of entry for electrons donated by NADH into the respiratory chain. Human cDNA fragments of the 51-kDa protein were generated by polymerase chain reaction and used to localize the gene (NDUFV1) for this subunit to 11q13 by two separate techniques. This region of the human genome is strongly implicated in a number of different forms of cancer.en_HK
dc.languageengen_HK
dc.publisherAcademic Press. The Journal's web site is located at http://www.elsevier.com/locate/ygenoen_HK
dc.relation.ispartofGenomics-
dc.subject.meshChromosomes, human, pair 11en_HK
dc.subject.meshCloning, molecularen_HK
dc.subject.meshElectron transport complex ien_HK
dc.subject.meshIn situ hybridizationen_HK
dc.subject.meshMitochondria - enzymologyen_HK
dc.titleChromosomal localization of the human gene encoding the 51-kDa subunit of mitochondrial complex I (NDUFV1) to 11q13en_HK
dc.typeArticleen_HK
dc.description.naturelink_to_subscribed_fulltexten_HK
dc.identifier.doi10.1006/geno.1993.1493en_HK
dc.identifier.pmid8288251-
dc.identifier.scopuseid_2-s2.0-0027427262-
dc.identifier.isiWOS:A1993MG99300042-

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