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- Publisher Website: 10.1006/geno.1993.1493
- Scopus: eid_2-s2.0-0027427262
- PMID: 8288251
- WOS: WOS:A1993MG99300042
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Article: Chromosomal localization of the human gene encoding the 51-kDa subunit of mitochondrial complex I (NDUFV1) to 11q13
Title | Chromosomal localization of the human gene encoding the 51-kDa subunit of mitochondrial complex I (NDUFV1) to 11q13 |
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Authors | |
Issue Date | 1993 |
Publisher | Academic Press. The Journal's web site is located at http://www.elsevier.com/locate/ygeno |
Citation | Genomics, 1993, v. 18 n. 2, p. 435-439 How to Cite? |
Abstract | The 51-kDa flavoprotein subunit of mitochondrial NADH:ubiquinone oxidoreductase (Complex I) [NADH dehydrogenase (ubiquinone), flavoprotein 1 (51 kDa); EC 1.6.5.3] plays an important role in the formation of the NADH-binding site and is believed to be the principal site of entry for electrons donated by NADH into the respiratory chain. Human cDNA fragments of the 51-kDa protein were generated by polymerase chain reaction and used to localize the gene (NDUFV1) for this subunit to 11q13 by two separate techniques. This region of the human genome is strongly implicated in a number of different forms of cancer. |
Persistent Identifier | http://hdl.handle.net/10722/44268 |
ISSN | 2023 Impact Factor: 3.4 2023 SCImago Journal Rankings: 0.850 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Ali, ST | en_HK |
dc.contributor.author | Duncan, AMV | en_HK |
dc.contributor.author | Schappert, K | en_HK |
dc.contributor.author | Heng, HHQ | en_HK |
dc.contributor.author | Tsui, L-C | en_HK |
dc.contributor.author | Chow, W | en_HK |
dc.contributor.author | Robinson, BH | en_HK |
dc.date.accessioned | 2007-09-12T03:50:17Z | - |
dc.date.available | 2007-09-12T03:50:17Z | - |
dc.date.issued | 1993 | en_HK |
dc.identifier.citation | Genomics, 1993, v. 18 n. 2, p. 435-439 | en_HK |
dc.identifier.issn | 0888-7543 | en_HK |
dc.identifier.uri | http://hdl.handle.net/10722/44268 | - |
dc.description.abstract | The 51-kDa flavoprotein subunit of mitochondrial NADH:ubiquinone oxidoreductase (Complex I) [NADH dehydrogenase (ubiquinone), flavoprotein 1 (51 kDa); EC 1.6.5.3] plays an important role in the formation of the NADH-binding site and is believed to be the principal site of entry for electrons donated by NADH into the respiratory chain. Human cDNA fragments of the 51-kDa protein were generated by polymerase chain reaction and used to localize the gene (NDUFV1) for this subunit to 11q13 by two separate techniques. This region of the human genome is strongly implicated in a number of different forms of cancer. | en_HK |
dc.language | eng | en_HK |
dc.publisher | Academic Press. The Journal's web site is located at http://www.elsevier.com/locate/ygeno | en_HK |
dc.relation.ispartof | Genomics | - |
dc.subject.mesh | Chromosomes, human, pair 11 | en_HK |
dc.subject.mesh | Cloning, molecular | en_HK |
dc.subject.mesh | Electron transport complex i | en_HK |
dc.subject.mesh | In situ hybridization | en_HK |
dc.subject.mesh | Mitochondria - enzymology | en_HK |
dc.title | Chromosomal localization of the human gene encoding the 51-kDa subunit of mitochondrial complex I (NDUFV1) to 11q13 | en_HK |
dc.type | Article | en_HK |
dc.description.nature | link_to_subscribed_fulltext | en_HK |
dc.identifier.doi | 10.1006/geno.1993.1493 | en_HK |
dc.identifier.pmid | 8288251 | - |
dc.identifier.scopus | eid_2-s2.0-0027427262 | - |
dc.identifier.isi | WOS:A1993MG99300042 | - |
dc.identifier.issnl | 0888-7543 | - |