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Article: Refined localization and yeast artificial chromosome (YAC) contig-mapping of genes and DNA segments in the 7q21-q32 region

TitleRefined localization and yeast artificial chromosome (YAC) contig-mapping of genes and DNA segments in the 7q21-q32 region
Authors
Scherer, SWRommens, JMSoder, SWong, EPlavsic, NTompkins, BJFBeattie, AKim, JTsui, LC
Issue Date1993
PublisherOxford University Press. The Journal's web site is located at http://hmg.oxfordjournals.org/
Citation
Human Molecular Genetics, 1993, v. 2 n. 6, p. 751-760 How to Cite?
DOI: http://dx.doi.org/10.1093/hmg/2.6.751
AbstractThe chromosome localizations for 159 gene and DNA segments have been refined to one of five intervals in the 7q21-q32 region through hybridization analysis with a panel of somatic cell hybrid lines. Seventy-two of these chromosome 7 markers are also mapped on common or overlapping yeast artificial chromosome (YAC) clones. In addition, the breakpoints of chromosome rearrangment contained in five of the somatic cell hybrid lines have been defined by flanking probes within YAC contigs. To provide a framework for further mapping of the 7q21-q32 region, we have established the physical order of a set of reference markers: cen-(COL1A2-D7S15-CYP3A4-PON)-D7S456-(breakpoint contained in cell hybrid 1EF2/3/K017)-GUSB-D7S186-ASL-(PGY1-PGY3-GNB2-EPO-ACHE)-D7S238- (proximal breakpoint in GM1059-Rag5)-D7S240-(CUTL1-PLANHI)-(breakpoints in 1CF2/5/K016 and 2068Rag22-2)-(PRKAR2B-D7S13)-LAMB1-(breakpoint in JSR-17S)-DLD-D7S16-MET-WNT2-CFTR-D7S8-tel.
Persistent Identifierhttp://hdl.handle.net/10722/44264
ISSN
0964-6906
2023 Impact Factor: 3.1
2023 SCImago Journal Rankings: 1.602
ISI Accession Number ID
WOS:A1993LH89200022

 

DC FieldValueLanguage
dc.contributor.authorScherer, SWen_HK
dc.contributor.authorRommens, JMen_HK
dc.contributor.authorSoder, Sen_HK
dc.contributor.authorWong, Een_HK
dc.contributor.authorPlavsic, Nen_HK
dc.contributor.authorTompkins, BJFen_HK
dc.contributor.authorBeattie, Aen_HK
dc.contributor.authorKim, Jen_HK
dc.contributor.authorTsui, LCen_HK
dc.date.accessioned2007-09-12T03:50:12Z-
dc.date.available2007-09-12T03:50:12Z-
dc.date.issued1993en_HK
dc.identifier.citationHuman Molecular Genetics, 1993, v. 2 n. 6, p. 751-760en_HK
dc.identifier.issn0964-6906en_HK
dc.identifier.urihttp://hdl.handle.net/10722/44264-
dc.description.abstractThe chromosome localizations for 159 gene and DNA segments have been refined to one of five intervals in the 7q21-q32 region through hybridization analysis with a panel of somatic cell hybrid lines. Seventy-two of these chromosome 7 markers are also mapped on common or overlapping yeast artificial chromosome (YAC) clones. In addition, the breakpoints of chromosome rearrangment contained in five of the somatic cell hybrid lines have been defined by flanking probes within YAC contigs. To provide a framework for further mapping of the 7q21-q32 region, we have established the physical order of a set of reference markers: cen-(COL1A2-D7S15-CYP3A4-PON)-D7S456-(breakpoint contained in cell hybrid 1EF2/3/K017)-GUSB-D7S186-ASL-(PGY1-PGY3-GNB2-EPO-ACHE)-D7S238- (proximal breakpoint in GM1059-Rag5)-D7S240-(CUTL1-PLANHI)-(breakpoints in 1CF2/5/K016 and 2068Rag22-2)-(PRKAR2B-D7S13)-LAMB1-(breakpoint in JSR-17S)-DLD-D7S16-MET-WNT2-CFTR-D7S8-tel.en_HK
dc.languageengen_HK
dc.publisherOxford University Press. The Journal's web site is located at http://hmg.oxfordjournals.org/en_HK
dc.relation.ispartofHuman Molecular Geneticsen_HK
dc.subject.meshChromosome walkingen_HK
dc.subject.meshChromosomes, fungalen_HK
dc.subject.meshChromosomes, human, pair 7en_HK
dc.subject.meshGene libraryen_HK
dc.subject.meshGenome, humanen_HK
dc.titleRefined localization and yeast artificial chromosome (YAC) contig-mapping of genes and DNA segments in the 7q21-q32 regionen_HK
dc.typeArticleen_HK
dc.identifier.emailTsui, LC: tsuilc@hkucc.hku.hken_HK
dc.identifier.authorityTsui, LC=rp00058en_HK
dc.description.naturelink_to_subscribed_fulltexten_HK
dc.identifier.doi10.1093/hmg/2.6.751-
dc.identifier.pmid8353494-
dc.identifier.scopuseid_2-s2.0-0027299880en_HK
dc.identifier.volume2en_HK
dc.identifier.issue6en_HK
dc.identifier.spage751en_HK
dc.identifier.epage760en_HK
dc.identifier.isiWOS:A1993LH89200022-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridScherer, SW=35374654500en_HK
dc.identifier.scopusauthoridRommens, JM=7006884140en_HK
dc.identifier.scopusauthoridSoder, S=6602121375en_HK
dc.identifier.scopusauthoridWong, E=7403161523en_HK
dc.identifier.scopusauthoridPlavsic, N=8314412600en_HK
dc.identifier.scopusauthoridTompkins, BJF=6701516907en_HK
dc.identifier.scopusauthoridBeattie, A=7006087909en_HK
dc.identifier.scopusauthoridKim, J=7601364811en_HK
dc.identifier.scopusauthoridTsui, LC=7102754167en_HK
dc.identifier.issnl0964-6906-

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