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Article: Twenty-five loci form a continuous linkage map of markers for human chromosome 7

TitleTwenty-five loci form a continuous linkage map of markers for human chromosome 7
Authors
Issue Date1989
PublisherAcademic Press. The Journal's web site is located at http://www.elsevier.com/locate/ygeno
Citation
Genomics, 1989, v. 5 n. 4, p. 866-873 How to Cite?
AbstractWe have constructed a primary genetic linkage map from DNA markers that define 25 loci on chromosome 7. The markers form a continuous linkage group of 141 cM in males and 340 cM in females; female genetic distances were on average more than twofold higher than those in males throughout the chromosome. The average heterozygosity of the loci was 45%. A subset of the markers can be used for efficient application of this map to studies of human genetic disease. © 1989.
Persistent Identifierhttp://hdl.handle.net/10722/44233
ISSN
2015 Impact Factor: 2.386
2015 SCImago Journal Rankings: 1.281
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorLathrop, GMen_HK
dc.contributor.authorO'Connell, Pen_HK
dc.contributor.authorLeppert, Men_HK
dc.contributor.authorNakamura, Yen_HK
dc.contributor.authorFarrall, Men_HK
dc.contributor.authorTsui, LCen_HK
dc.contributor.authorLalouel, JMen_HK
dc.contributor.authorWhite, Ren_HK
dc.date.accessioned2007-09-12T03:49:32Z-
dc.date.available2007-09-12T03:49:32Z-
dc.date.issued1989en_HK
dc.identifier.citationGenomics, 1989, v. 5 n. 4, p. 866-873en_HK
dc.identifier.issn0888-7543en_HK
dc.identifier.urihttp://hdl.handle.net/10722/44233-
dc.description.abstractWe have constructed a primary genetic linkage map from DNA markers that define 25 loci on chromosome 7. The markers form a continuous linkage group of 141 cM in males and 340 cM in females; female genetic distances were on average more than twofold higher than those in males throughout the chromosome. The average heterozygosity of the loci was 45%. A subset of the markers can be used for efficient application of this map to studies of human genetic disease. © 1989.en_HK
dc.languageengen_HK
dc.publisherAcademic Press. The Journal's web site is located at http://www.elsevier.com/locate/ygenoen_HK
dc.relation.ispartofGenomicsen_HK
dc.subject.meshAllelesen_HK
dc.subject.meshChromosome mappingen_HK
dc.subject.meshChromosomes, human, pair 7en_HK
dc.subject.meshCrossing over, geneticen_HK
dc.subject.meshGenetic markersen_HK
dc.titleTwenty-five loci form a continuous linkage map of markers for human chromosome 7en_HK
dc.typeArticleen_HK
dc.identifier.emailTsui, LC: tsuilc@hkucc.hku.hken_HK
dc.identifier.authorityTsui, LC=rp00058en_HK
dc.description.naturelink_to_subscribed_fulltexten_HK
dc.identifier.doi10.1016/0888-7543(89)90128-6en_HK
dc.identifier.pmid2591968-
dc.identifier.scopuseid_2-s2.0-0024763772en_HK
dc.identifier.volume5en_HK
dc.identifier.issue4en_HK
dc.identifier.spage866en_HK
dc.identifier.epage873en_HK
dc.identifier.isiWOS:A1989AZ32800023-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridLathrop, GM=7102890692en_HK
dc.identifier.scopusauthoridO'Connell, P=7202733781en_HK
dc.identifier.scopusauthoridLeppert, M=35351313000en_HK
dc.identifier.scopusauthoridNakamura, Y=36013862000en_HK
dc.identifier.scopusauthoridFarrall, M=7006468255en_HK
dc.identifier.scopusauthoridTsui, LC=7102754167en_HK
dc.identifier.scopusauthoridLalouel, JM=7102287621en_HK
dc.identifier.scopusauthoridWhite, R=7501421957en_HK

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