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Article: Influenza-associated mortality in Hong Kong
Title | Influenza-associated mortality in Hong Kong |
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Authors | |
Issue Date | 2004 |
Publisher | Oxford University Press. The Journal's web site is located at http://www.oxfordjournals.org/our_journals/cid/ |
Citation | Clinical Infectious Diseases, 2004, v. 39 n. 11, p. 1611-1617 How to Cite? |
Abstract | Background. The impact of influenza on mortality in countries in subtropical and tropical regions is poorly quantified. Estimation of influenza-related illness in warm-climate regions is more difficult, because the seasonality of virus circulation is less well-defined. Partly as a result of these factors, influenza vaccine is grossly underutilized in the tropics, even for individuals ≥65 years of age. Methods. Weekly numbers of deaths were modeled by Poisson regression, and excess deaths attributable to influenza in Hong Kong were estimated for 1996-1999. Comparison of weekly mortality during periods of influenza predominance and periods of low influenza activity was used to derive an alternative estimate of influenza-associated mortality. Results. Estimates derived from the Poisson model indicated that influenza resulted in 7.3 deaths per 100,000 population per year (95% confidence interval [CI], 3.1-11.4) from cardiorespiratory disease among individuals aged 40-65 years and 102.0 deaths per 100,000 per population per year (95% CI, 61.2-142.7) among individuals aged ≥65 years. Although respiratory diseases accounted for the majority of influenza-related deaths, influenza also contributed to 13.8% (95% CI, 4.8%- 22.7%) and 5.3% (95% CI, 1.2%-9.3%) of deaths related to ischemic heart disease. Conclusion. Influenza is associated with deaths due to ischemic heart disease as well from respiratory diseases. Overall influenza-associated mortality in a region with a warm climate, such as Hong Kong, is comparable with that documented in temperate regions. The need for influenza vaccination in tropical regions needs to be reassessed. |
Persistent Identifier | http://hdl.handle.net/10722/43588 |
ISSN | 2023 Impact Factor: 8.2 2023 SCImago Journal Rankings: 3.308 |
ISI Accession Number ID | |
References |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Wong, CM | en_HK |
dc.contributor.author | Chan, KP | en_HK |
dc.contributor.author | Hedley, AJ | en_HK |
dc.contributor.author | Peiris, JSM | en_HK |
dc.date.accessioned | 2007-03-23T04:49:40Z | - |
dc.date.available | 2007-03-23T04:49:40Z | - |
dc.date.issued | 2004 | en_HK |
dc.identifier.citation | Clinical Infectious Diseases, 2004, v. 39 n. 11, p. 1611-1617 | en_HK |
dc.identifier.issn | 1058-4838 | en_HK |
dc.identifier.uri | http://hdl.handle.net/10722/43588 | - |
dc.description.abstract | Background. The impact of influenza on mortality in countries in subtropical and tropical regions is poorly quantified. Estimation of influenza-related illness in warm-climate regions is more difficult, because the seasonality of virus circulation is less well-defined. Partly as a result of these factors, influenza vaccine is grossly underutilized in the tropics, even for individuals ≥65 years of age. Methods. Weekly numbers of deaths were modeled by Poisson regression, and excess deaths attributable to influenza in Hong Kong were estimated for 1996-1999. Comparison of weekly mortality during periods of influenza predominance and periods of low influenza activity was used to derive an alternative estimate of influenza-associated mortality. Results. Estimates derived from the Poisson model indicated that influenza resulted in 7.3 deaths per 100,000 population per year (95% confidence interval [CI], 3.1-11.4) from cardiorespiratory disease among individuals aged 40-65 years and 102.0 deaths per 100,000 per population per year (95% CI, 61.2-142.7) among individuals aged ≥65 years. Although respiratory diseases accounted for the majority of influenza-related deaths, influenza also contributed to 13.8% (95% CI, 4.8%- 22.7%) and 5.3% (95% CI, 1.2%-9.3%) of deaths related to ischemic heart disease. Conclusion. Influenza is associated with deaths due to ischemic heart disease as well from respiratory diseases. Overall influenza-associated mortality in a region with a warm climate, such as Hong Kong, is comparable with that documented in temperate regions. The need for influenza vaccination in tropical regions needs to be reassessed. | en_HK |
dc.format.extent | 214301 bytes | - |
dc.format.extent | 25600 bytes | - |
dc.format.extent | 2912 bytes | - |
dc.format.mimetype | application/pdf | - |
dc.format.mimetype | application/msword | - |
dc.format.mimetype | text/plain | - |
dc.language | eng | en_HK |
dc.publisher | Oxford University Press. The Journal's web site is located at http://www.oxfordjournals.org/our_journals/cid/ | en_HK |
dc.relation.ispartof | Clinical Infectious Diseases | en_HK |
dc.rights | Clinical Infectious Diseases. Copyright © University of Chicago Press. | en_HK |
dc.subject.mesh | Hong kong - epidemiology | en_HK |
dc.subject.mesh | Cause of death | en_HK |
dc.subject.mesh | Influenza, human | en_HK |
dc.subject.mesh | Adult | en_HK |
dc.subject.mesh | Mortality | en_HK |
dc.title | Influenza-associated mortality in Hong Kong | en_HK |
dc.type | Article | en_HK |
dc.identifier.openurl | http://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1058-4838&volume=39&issue=11&spage=1611&epage=1617&date=2004&atitle=Influenza-associated+mortality+in+Hong+Kong | en_HK |
dc.identifier.email | Wong, CM: hrmrwcm@hku.hk | en_HK |
dc.identifier.email | Hedley, AJ: hrmrajh@hkucc.hku.hk | en_HK |
dc.identifier.email | Peiris, JSM: malik@hkucc.hku.hk | en_HK |
dc.identifier.authority | Wong, CM=rp00338 | en_HK |
dc.identifier.authority | Hedley, AJ=rp00357 | en_HK |
dc.identifier.authority | Peiris, JSM=rp00410 | en_HK |
dc.description.nature | published_or_final_version | en_HK |
dc.identifier.doi | 10.1086/425315 | en_HK |
dc.identifier.pmid | 15578360 | - |
dc.identifier.scopus | eid_2-s2.0-9644276994 | en_HK |
dc.identifier.hkuros | 96818 | - |
dc.relation.references | http://www.scopus.com/mlt/select.url?eid=2-s2.0-9644276994&selection=ref&src=s&origin=recordpage | en_HK |
dc.identifier.volume | 39 | en_HK |
dc.identifier.issue | 11 | en_HK |
dc.identifier.spage | 1611 | en_HK |
dc.identifier.epage | 1617 | en_HK |
dc.identifier.isi | WOS:000227492100009 | - |
dc.publisher.place | United States | en_HK |
dc.identifier.scopusauthorid | Wong, CM=7404954904 | en_HK |
dc.identifier.scopusauthorid | Chan, KP=27171298000 | en_HK |
dc.identifier.scopusauthorid | Hedley, AJ=7102584095 | en_HK |
dc.identifier.scopusauthorid | Peiris, JSM=7005486823 | en_HK |
dc.identifier.issnl | 1058-4838 | - |