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Article: Comparison between two districts of the effects of an air pollution intervention on bronchial responsiveness in primary school children in Hong Kong

TitleComparison between two districts of the effects of an air pollution intervention on bronchial responsiveness in primary school children in Hong Kong
Authors
Issue Date1998
PublisherB M J Publishing Group. The Journal's web site is located at http://jech.bmjjournals.com/
Citation
Journal Of Epidemiology And Community Health, 1998, v. 52 n. 9, p. 571-578 How to Cite?
AbstractStudy objective - This study examined the impact on children's respiratory health of a government air quality intervention that restricted the sulphur content of fuels to 0.5% from July 1990 onwards. Design/setting/participants - This study examined the changes, one and two years after the introduction of the intervention, in airway hyperreactivity of non-asthmatic and non-wheezing, primary 4, 5, and 6, school children aged 9-12 years living in a polluted district compared with those in a less polluted district. Bronchial hyperreactivity (BHR) (a 20% decrease in FEV, provoked by a cumulative dose of histamine less than 7.8 μmol) and bronchial reactivity slope (BR slope) (percentage change in logarithmic scale in FEV, per unit dose of histamine) were used to estimate responses to a histamine challenge. The between districts differences after the intervention were studied to assess the effectiveness of the intervention. Main results - In cohorts, comparing measurements made before the intervention and one year afterwards, both BHR and BR slope declined from 29% to 16% (p = 0.026) and from 48 to 39 (p = 0.075) respectively in the polluted district; and from 21% to 10% (p = 0.001) and 42 to 36 (p > 0.100) in the less polluted district. Comparing measurements made in 1991 (one year after intervention) with those in 1992 (two years after intervention), only the polluted district showed a significant decline from 28% to 12% (p = 0.016) and from 46 to 35 (p = 0.014), for BHR and BR slope respectively, with a greater decline in both responses (p = 0.018 and 0.073) than in the less polluted district. Conclusion - Bronchial hyperresponsiveness tests can be used to support the evaluation of an air quality intervention. The demonstrated reduction in bronchial hyperresponsiveness is an indication of the effectiveness of the intervention.
Persistent Identifierhttp://hdl.handle.net/10722/43567
ISSN
2015 Impact Factor: 3.865
2015 SCImago Journal Rankings: 1.890
PubMed Central ID
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorWong, CMen_HK
dc.contributor.authorLam, THen_HK
dc.contributor.authorPeters, Jen_HK
dc.contributor.authorHedley, AJen_HK
dc.contributor.authorOng, SGen_HK
dc.contributor.authorTam, AYCen_HK
dc.contributor.authorLiu, Jen_HK
dc.contributor.authorSpiegelhalter, DJen_HK
dc.date.accessioned2007-03-23T04:49:12Z-
dc.date.available2007-03-23T04:49:12Z-
dc.date.issued1998en_HK
dc.identifier.citationJournal Of Epidemiology And Community Health, 1998, v. 52 n. 9, p. 571-578en_HK
dc.identifier.issn0143-005Xen_HK
dc.identifier.urihttp://hdl.handle.net/10722/43567-
dc.description.abstractStudy objective - This study examined the impact on children's respiratory health of a government air quality intervention that restricted the sulphur content of fuels to 0.5% from July 1990 onwards. Design/setting/participants - This study examined the changes, one and two years after the introduction of the intervention, in airway hyperreactivity of non-asthmatic and non-wheezing, primary 4, 5, and 6, school children aged 9-12 years living in a polluted district compared with those in a less polluted district. Bronchial hyperreactivity (BHR) (a 20% decrease in FEV, provoked by a cumulative dose of histamine less than 7.8 μmol) and bronchial reactivity slope (BR slope) (percentage change in logarithmic scale in FEV, per unit dose of histamine) were used to estimate responses to a histamine challenge. The between districts differences after the intervention were studied to assess the effectiveness of the intervention. Main results - In cohorts, comparing measurements made before the intervention and one year afterwards, both BHR and BR slope declined from 29% to 16% (p = 0.026) and from 48 to 39 (p = 0.075) respectively in the polluted district; and from 21% to 10% (p = 0.001) and 42 to 36 (p > 0.100) in the less polluted district. Comparing measurements made in 1991 (one year after intervention) with those in 1992 (two years after intervention), only the polluted district showed a significant decline from 28% to 12% (p = 0.016) and from 46 to 35 (p = 0.014), for BHR and BR slope respectively, with a greater decline in both responses (p = 0.018 and 0.073) than in the less polluted district. Conclusion - Bronchial hyperresponsiveness tests can be used to support the evaluation of an air quality intervention. The demonstrated reduction in bronchial hyperresponsiveness is an indication of the effectiveness of the intervention.en_HK
dc.format.extent173850 bytes-
dc.format.extent25600 bytes-
dc.format.mimetypeapplication/pdf-
dc.format.mimetypeapplication/msword-
dc.languageengen_HK
dc.publisherB M J Publishing Group. The Journal's web site is located at http://jech.bmjjournals.com/en_HK
dc.relation.ispartofJournal of Epidemiology and Community Healthen_HK
dc.rightsJournal of Epidemiology & Community Health. Copyright © B M J Publishing Group.en_HK
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.subject.meshAir pollutants - adverse effectsen_HK
dc.subject.meshAir pollution - legislation & jurisprudence - prevention & controlen_HK
dc.subject.meshBronchial hyperreactivity - chemically induced - diagnosisen_HK
dc.subject.meshSulfur dioxide - adverse effectsen_HK
dc.subject.meshCohort studiesen_HK
dc.titleComparison between two districts of the effects of an air pollution intervention on bronchial responsiveness in primary school children in Hong Kongen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0143-005X&volume=52&issue=9&spage=571&epage=578&date=1998&atitle=Comparison+between+two+districts+of+the+effects+of+an+air+pollution+intervention+on+bronchial+responsiveness+in+primary+school+children+in+Hong+Kongen_HK
dc.identifier.emailWong, CM:hrmrwcm@hkucc.hku.hken_HK
dc.identifier.emailLam, TH:hrmrlth@hkucc.hku.hken_HK
dc.identifier.emailHedley, AJ:hrmrajh@hkucc.hku.hken_HK
dc.identifier.authorityWong, CM=rp00338en_HK
dc.identifier.authorityLam, TH=rp00326en_HK
dc.identifier.authorityHedley, AJ=rp00357en_HK
dc.description.naturepublished_or_final_versionen_HK
dc.identifier.pmid10320858-
dc.identifier.pmcidPMC1756761-
dc.identifier.scopuseid_2-s2.0-0031692065en_HK
dc.identifier.hkuros39097-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0031692065&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume52en_HK
dc.identifier.issue9en_HK
dc.identifier.spage571en_HK
dc.identifier.epage578en_HK
dc.identifier.isiWOS:000075566400006-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridWong, CM=7404954904en_HK
dc.identifier.scopusauthoridLam, TH=7202522876en_HK
dc.identifier.scopusauthoridPeters, J=24784601400en_HK
dc.identifier.scopusauthoridHedley, AJ=7102584095en_HK
dc.identifier.scopusauthoridOng, SG=7202336734en_HK
dc.identifier.scopusauthoridTam, AYC=7101744914en_HK
dc.identifier.scopusauthoridLiu, J=15319295700en_HK
dc.identifier.scopusauthoridSpiegelhalter, DJ=35491822900en_HK

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