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Article: Antigenic cross-reactivity between severe acute respiratory syndrome-associated coronavirus and human coronaviruses 229E and OC43

TitleAntigenic cross-reactivity between severe acute respiratory syndrome-associated coronavirus and human coronaviruses 229E and OC43
Authors
Che, XYQiu, LWLiao, ZYWang, YDWen, KPan, YXHao, WMei, YBCheng, VCCYuen, KY
Issue Date2005
PublisherOxford University Press. The Journal's web site is located at http://jid.oxfordjournals.org
Citation
Journal Of Infectious Diseases, 2005, v. 191 n. 12, p. 2033-2037 How to Cite?
DOI: http://dx.doi.org/10.1086/430355
AbstractCross-reactivity between antibodies to different human coronaviruses (HCoVs) has not been systematically studied. By use of Western blot analysis, indirect immunofluorescence assay (IFA), and enzyme-linked immunosorbent assay (ELISA), antigenic cross-reactivity between severe acute respiratory syndrome (SARS)-associated coronavirus (SARS-CoV) and 2 HCoVs (229E and OC43) was demonstrated in immunized animals and human serum. In 5 of 11 and 10 of 11 patients with SARS, paired serum samples showed a ≥4-fold increase in antibody titers against HCoV-229E and HCoV-OC43, respectively, by IFA. Overall, serum samples from convalescent patients who had SARS had a 1-way cross-reactivity with the 2 known HCoVs. Antigens of SARS-CoV and HCoV-OC43 were more cross-reactive than were those of SARS-CoV and HCoV-229E. © 2005 by the Infectious Diseases Society of America. All rights reserved.
Persistent Identifierhttp://hdl.handle.net/10722/43117
ISSN
0022-1899
2023 Impact Factor: 5.0
2023 SCImago Journal Rankings: 2.387
ISI Accession Number ID
WOS:000229203900006
References
References in Scopus

 

DC FieldValueLanguage
dc.contributor.authorChe, XYen_HK
dc.contributor.authorQiu, LWen_HK
dc.contributor.authorLiao, ZYen_HK
dc.contributor.authorWang, YDen_HK
dc.contributor.authorWen, Ken_HK
dc.contributor.authorPan, YXen_HK
dc.contributor.authorHao, Wen_HK
dc.contributor.authorMei, YBen_HK
dc.contributor.authorCheng, VCCen_HK
dc.contributor.authorYuen, KYen_HK
dc.date.accessioned2007-03-23T04:39:16Z-
dc.date.available2007-03-23T04:39:16Z-
dc.date.issued2005en_HK
dc.identifier.citationJournal Of Infectious Diseases, 2005, v. 191 n. 12, p. 2033-2037en_HK
dc.identifier.issn0022-1899en_HK
dc.identifier.urihttp://hdl.handle.net/10722/43117-
dc.description.abstractCross-reactivity between antibodies to different human coronaviruses (HCoVs) has not been systematically studied. By use of Western blot analysis, indirect immunofluorescence assay (IFA), and enzyme-linked immunosorbent assay (ELISA), antigenic cross-reactivity between severe acute respiratory syndrome (SARS)-associated coronavirus (SARS-CoV) and 2 HCoVs (229E and OC43) was demonstrated in immunized animals and human serum. In 5 of 11 and 10 of 11 patients with SARS, paired serum samples showed a ≥4-fold increase in antibody titers against HCoV-229E and HCoV-OC43, respectively, by IFA. Overall, serum samples from convalescent patients who had SARS had a 1-way cross-reactivity with the 2 known HCoVs. Antigens of SARS-CoV and HCoV-OC43 were more cross-reactive than were those of SARS-CoV and HCoV-229E. © 2005 by the Infectious Diseases Society of America. All rights reserved.en_HK
dc.format.extent474921 bytes-
dc.format.extent30720 bytes-
dc.format.mimetypeapplication/pdf-
dc.format.mimetypeapplication/msword-
dc.languageengen_HK
dc.publisherOxford University Press. The Journal's web site is located at http://jid.oxfordjournals.org en_HK
dc.relation.ispartofJournal of Infectious Diseasesen_HK
dc.rightsJournal of Infectious Diseases. Copyright © University of Chicago Press.en_HK
dc.subject.meshAntigens, viral - blooden_HK
dc.subject.meshCoronavirus 229e, human - immunologyen_HK
dc.subject.meshCoronavirus oc43, human - immunologyen_HK
dc.subject.meshSars virus - immunologyen_HK
dc.subject.meshAntibodies, viral - blooden_HK
dc.titleAntigenic cross-reactivity between severe acute respiratory syndrome-associated coronavirus and human coronaviruses 229E and OC43en_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0022-1899&volume=191&issue=12&spage=2033&epage=2037&date=2005&atitle=Antigenic+cross-reactivity+between+severe+acute+respiratory+syndrome-associated+coronavirus+and+human+coronaviruses+229E+and+OC43en_HK
dc.identifier.emailYuen, KY:kyyuen@hkucc.hku.hken_HK
dc.identifier.authorityYuen, KY=rp00366en_HK
dc.description.naturepublished_or_final_versionen_HK
dc.identifier.doi10.1086/430355en_HK
dc.identifier.pmid15897988en_HK
dc.identifier.scopuseid_2-s2.0-20444399476en_HK
dc.identifier.hkuros100344-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-20444399476&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume191en_HK
dc.identifier.issue12en_HK
dc.identifier.spage2033en_HK
dc.identifier.epage2037en_HK
dc.identifier.isiWOS:000229203900006-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridChe, XY=7005743182en_HK
dc.identifier.scopusauthoridQiu, LW=8719102700en_HK
dc.identifier.scopusauthoridLiao, ZY=7203032864en_HK
dc.identifier.scopusauthoridWang, YD=9638471800en_HK
dc.identifier.scopusauthoridWen, K=8231190100en_HK
dc.identifier.scopusauthoridPan, YX=35765899800en_HK
dc.identifier.scopusauthoridHao, W=7101686587en_HK
dc.identifier.scopusauthoridMei, YB=8231190400en_HK
dc.identifier.scopusauthoridCheng, VCC=23670479400en_HK
dc.identifier.scopusauthoridYuen, KY=36078079100en_HK
dc.identifier.issnl0022-1899-

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