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Article: Refined localization of the asparagine synthetase gene (ASNS) to chromosome 7, region q21.3, and characterization of the somatic cell hybrid line 4AF/106/K015

TitleRefined localization of the asparagine synthetase gene (ASNS) to chromosome 7, region q21.3, and characterization of the somatic cell hybrid line 4AF/106/K015
Authors
KeywordsBiology
Genetics biology
Cytology and histology
Issue Date1994
PublisherS Karger AG. The Journal's web site is located at http://www.karger.com/CGR
Citation
Cytogenetics And Cell Genetics, 1994, v. 66 n. 2, p. 135-138 How to Cite?
AbstractWe have mapped the asparagine synthetase gene (ASNS) to 7q21.3 by fluorescence in situ hybridization. While this study refined the localization of the gene, it also revealed a rearrangement in a somatic cell hybrid line which was used in previous ASNS mapping. Using additional probes from other regions of human chromosome 7, we showed that this cell line (4AF/106/KO15) contained a rearranged chromosome 7 in which a segment of the long arm was apparently duplicated and inserted into the short arm. Caution should be used therefore when interpreting data obtained from this cell line for gene mapping studies.
Persistent Identifierhttp://hdl.handle.net/10722/42532
ISSN
2003 Impact Factor: 1.162
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorHeng, HHQen_HK
dc.contributor.authorShi, XMen_HK
dc.contributor.authorScherer, SWen_HK
dc.contributor.authorAndrulis, ILen_HK
dc.contributor.authorTsui, LCen_HK
dc.date.accessioned2007-01-29T08:52:20Z-
dc.date.available2007-01-29T08:52:20Z-
dc.date.issued1994en_HK
dc.identifier.citationCytogenetics And Cell Genetics, 1994, v. 66 n. 2, p. 135-138en_HK
dc.identifier.issn0301-0171en_HK
dc.identifier.urihttp://hdl.handle.net/10722/42532-
dc.description.abstractWe have mapped the asparagine synthetase gene (ASNS) to 7q21.3 by fluorescence in situ hybridization. While this study refined the localization of the gene, it also revealed a rearrangement in a somatic cell hybrid line which was used in previous ASNS mapping. Using additional probes from other regions of human chromosome 7, we showed that this cell line (4AF/106/KO15) contained a rearranged chromosome 7 in which a segment of the long arm was apparently duplicated and inserted into the short arm. Caution should be used therefore when interpreting data obtained from this cell line for gene mapping studies.en_HK
dc.format.extent932489 bytes-
dc.format.extent25088 bytes-
dc.format.mimetypeapplication/pdf-
dc.format.mimetypeapplication/msword-
dc.languageengen_HK
dc.publisherS Karger AG. The Journal's web site is located at http://www.karger.com/CGRen_HK
dc.relation.ispartofCytogenetics and Cell Geneticsen_HK
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.subjectBiologyen_HK
dc.subjectGenetics biologyen_HK
dc.subjectCytology and histologyen_HK
dc.titleRefined localization of the asparagine synthetase gene (ASNS) to chromosome 7, region q21.3, and characterization of the somatic cell hybrid line 4AF/106/K015en_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0301-0171&volume=66&spage=135&epage=138&date=1994&atitle=Refined+localization+of+the+asparagine+synthetase+gene+(ASNS)+to+chromosome+7,+region+q21.3,+and+characterization+of+the+somatic+cell+hybrid+line+4AF/106/KO15en_HK
dc.identifier.emailTsui, LC: tsuilc@hkucc.hku.hken_HK
dc.identifier.authorityTsui, LC=rp00058en_HK
dc.description.naturepublished_or_final_versionen_HK
dc.identifier.doi10.1159/000133685-
dc.identifier.pmid7904551-
dc.identifier.scopuseid_2-s2.0-0027952909en_HK
dc.identifier.volume66en_HK
dc.identifier.issue2en_HK
dc.identifier.spage135en_HK
dc.identifier.epage138en_HK
dc.identifier.isiWOS:A1994MV18600015-
dc.publisher.placeSwitzerlanden_HK
dc.identifier.scopusauthoridHeng, HHQ=7005338076en_HK
dc.identifier.scopusauthoridShi, XM=7402953863en_HK
dc.identifier.scopusauthoridScherer, SW=35374654500en_HK
dc.identifier.scopusauthoridAndrulis, IL=7005655442en_HK
dc.identifier.scopusauthoridTsui, LC=7102754167en_HK

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