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Article: siRNA delivery into human T cells and primary cells with carbon-nanotube transporters

TitlesiRNA delivery into human T cells and primary cells with carbon-nanotube transporters
Authors
Liu, ZhuangWinters, MarkHolodniy, MarkDai, Hongjie
KeywordsCarbon nanotubes
Drug delivery
Nanobiotechnology
RNA interference
T cells
Issue Date2007
Citation
Angewandte Chemie - International Edition, 2007, v. 46, n. 12, p. 2023-2027 How to Cite?
DOI: http://dx.doi.org/10.1002/anie.200604295
AbstractSpecial delivery: Functionalized single-walled nanotubes (SWNT) can be used as molecular transporters to shuttle short interfering RNA (siRNA) into human T cells and primary cells and silence the expression of HIV-specific cell-surface receptors and coreceptors (see picture; scale bars 40 μm). This silencing effect, known to block HIV viral entry and reduce infection, is superior to that observed with conventional liposome-based nonviral delivery agents. (Figure Presented). © 2007 Wiley-VCH Verlag GmbH & Co. KGaA.
Persistent Identifierhttp://hdl.handle.net/10722/334143
ISSN
1433-7851
2021 Impact Factor: 16.823
2020 SCImago Journal Rankings: 5.831

 

DC FieldValueLanguage
dc.contributor.authorLiu, Zhuang-
dc.contributor.authorWinters, Mark-
dc.contributor.authorHolodniy, Mark-
dc.contributor.authorDai, Hongjie-
dc.date.accessioned2023-10-20T06:46:02Z-
dc.date.available2023-10-20T06:46:02Z-
dc.date.issued2007-
dc.identifier.citationAngewandte Chemie - International Edition, 2007, v. 46, n. 12, p. 2023-2027-
dc.identifier.issn1433-7851-
dc.identifier.urihttp://hdl.handle.net/10722/334143-
dc.description.abstractSpecial delivery: Functionalized single-walled nanotubes (SWNT) can be used as molecular transporters to shuttle short interfering RNA (siRNA) into human T cells and primary cells and silence the expression of HIV-specific cell-surface receptors and coreceptors (see picture; scale bars 40 μm). This silencing effect, known to block HIV viral entry and reduce infection, is superior to that observed with conventional liposome-based nonviral delivery agents. (Figure Presented). © 2007 Wiley-VCH Verlag GmbH & Co. KGaA.-
dc.languageeng-
dc.relation.ispartofAngewandte Chemie - International Edition-
dc.subjectCarbon nanotubes-
dc.subjectDrug delivery-
dc.subjectNanobiotechnology-
dc.subjectRNA interference-
dc.subjectT cells-
dc.titlesiRNA delivery into human T cells and primary cells with carbon-nanotube transporters-
dc.typeArticle-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1002/anie.200604295-
dc.identifier.pmid17290476-
dc.identifier.scopuseid_2-s2.0-34247582332-
dc.identifier.volume46-
dc.identifier.issue12-
dc.identifier.spage2023-
dc.identifier.epage2027-

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