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Conference Paper: The role of central vestibular system in circadian rhythms?
| Title | The role of central vestibular system in circadian rhythms? |
|---|---|
| Authors | |
| Issue Date | 2021 |
| Publisher | International Society of Magnetic Resonance Imaging (ISMRM) . |
| Citation | Proceedings of the 29th Annual Meeting & Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM), Virtual Conference, Vancouver, BC, Canada, 15-20 May 2021, paper no. 2943 How to Cite? |
| Abstract | The vestibular system is critical for bodily functions, yet it remains an underappreciated sense. Recently, seminal studies of the prolonged exposure to microgravity in space showed significant alteration in vestibular activity and circadian rhythms. However, little is known regarding the role of the central vestibular system in regulating the circadian clock. Here, we deploy fMRI and optogenetic stimulation of vestibular excitatory neurons to visualize the neural targets of the vestibular system in circadian circuits. We reveal that the central vestibular system provides inputs to the suprachiasmatic nucleus, optic nerve and locus coeruleus, notable regions that drive and regulate circadian rhythms. |
| Description | Digital Posters - Session D-168: fMRI of Animal Models - fMRI Using Animal Models: Applications - no. 2943 |
| Persistent Identifier | http://hdl.handle.net/10722/304063 |
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Leong, TL | - |
| dc.contributor.author | Man, C | - |
| dc.contributor.author | Gu, Y | - |
| dc.contributor.author | Wu, EX | - |
| dc.date.accessioned | 2021-09-23T08:54:44Z | - |
| dc.date.available | 2021-09-23T08:54:44Z | - |
| dc.date.issued | 2021 | - |
| dc.identifier.citation | Proceedings of the 29th Annual Meeting & Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM), Virtual Conference, Vancouver, BC, Canada, 15-20 May 2021, paper no. 2943 | - |
| dc.identifier.uri | http://hdl.handle.net/10722/304063 | - |
| dc.description | Digital Posters - Session D-168: fMRI of Animal Models - fMRI Using Animal Models: Applications - no. 2943 | - |
| dc.description.abstract | The vestibular system is critical for bodily functions, yet it remains an underappreciated sense. Recently, seminal studies of the prolonged exposure to microgravity in space showed significant alteration in vestibular activity and circadian rhythms. However, little is known regarding the role of the central vestibular system in regulating the circadian clock. Here, we deploy fMRI and optogenetic stimulation of vestibular excitatory neurons to visualize the neural targets of the vestibular system in circadian circuits. We reveal that the central vestibular system provides inputs to the suprachiasmatic nucleus, optic nerve and locus coeruleus, notable regions that drive and regulate circadian rhythms. | - |
| dc.language | eng | - |
| dc.publisher | International Society of Magnetic Resonance Imaging (ISMRM) . | - |
| dc.relation.ispartof | ISMRM (International Society of Magnetic Resonance Imaging) Virtual Conference & Exhibition, 2021 | - |
| dc.title | The role of central vestibular system in circadian rhythms? | - |
| dc.type | Conference_Paper | - |
| dc.identifier.email | Leong, TL: tlleong@hku.hk | - |
| dc.identifier.email | Wu, EX: ewu@eee.hku.hk | - |
| dc.identifier.authority | Leong, TL=rp02483 | - |
| dc.identifier.authority | Wu, EX=rp00193 | - |
| dc.identifier.hkuros | 325454 | - |
| dc.identifier.spage | 2943 | - |
| dc.identifier.epage | 2943 | - |