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Conference Paper: The Mechanism of Spinal Cord Stimulation in Animal Model of Neuropathic Pain
| Title | The Mechanism of Spinal Cord Stimulation in Animal Model of Neuropathic Pain |
|---|---|
| Authors | |
| Issue Date | 2020 |
| Publisher | SAGE Publications. The Journal's web site is located at http://mpx.sagepub.com/home/ |
| Citation | The 8th Asian Pain Symposium (APS 2019), Songdo, Incheon, Republic of Korea, 5-7 December 2019. Abstracts in Molecular Pain, 2020, v. 16, p. 38 How to Cite? |
| Abstract | Spinal cord stimulation (SCS) has been shown to be effective in the management of certain neuropathic pain conditions; however, the underlying mechanisms are incompletely understood. Our study showed that the endocannabinoid system, and in particular the CB1 R, plays a pivotal role in the long-lasting and incremental reversal of hyperalgesia induced by repetitive SCS in a peripheral neuropathic pain model. Our another study demonstrated that spinal progenitor cells can be activated by SCS via descending pathways to relieve spinal cord injury-induced neuropathic pain. Further research direction in SCS using
neuropathic pain animal model will also be discussed. |
| Persistent Identifier | http://hdl.handle.net/10722/300758 |
| ISSN | 2021 Impact Factor: 3.370 2020 SCImago Journal Rankings: 1.081 |
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Cheung, CW | - |
| dc.date.accessioned | 2021-06-21T07:34:28Z | - |
| dc.date.available | 2021-06-21T07:34:28Z | - |
| dc.date.issued | 2020 | - |
| dc.identifier.citation | The 8th Asian Pain Symposium (APS 2019), Songdo, Incheon, Republic of Korea, 5-7 December 2019. Abstracts in Molecular Pain, 2020, v. 16, p. 38 | - |
| dc.identifier.issn | 1744-8069 | - |
| dc.identifier.uri | http://hdl.handle.net/10722/300758 | - |
| dc.description.abstract | Spinal cord stimulation (SCS) has been shown to be effective in the management of certain neuropathic pain conditions; however, the underlying mechanisms are incompletely understood. Our study showed that the endocannabinoid system, and in particular the CB1 R, plays a pivotal role in the long-lasting and incremental reversal of hyperalgesia induced by repetitive SCS in a peripheral neuropathic pain model. Our another study demonstrated that spinal progenitor cells can be activated by SCS via descending pathways to relieve spinal cord injury-induced neuropathic pain. Further research direction in SCS using neuropathic pain animal model will also be discussed. | - |
| dc.language | eng | - |
| dc.publisher | SAGE Publications. The Journal's web site is located at http://mpx.sagepub.com/home/ | - |
| dc.relation.ispartof | Molecular Pain | - |
| dc.relation.ispartof | The 8th Asian Pain Symposium (APS 2019) | - |
| dc.rights | This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. | - |
| dc.title | The Mechanism of Spinal Cord Stimulation in Animal Model of Neuropathic Pain | - |
| dc.type | Conference_Paper | - |
| dc.identifier.email | Cheung, CW: cheucw@hku.hk | - |
| dc.identifier.authority | Cheung, CW=rp00244 | - |
| dc.description.nature | published_or_final_version | - |
| dc.identifier.hkuros | 312899 | - |
| dc.identifier.volume | 16 | - |
| dc.identifier.spage | 38 | - |
| dc.identifier.epage | 38 | - |
| dc.publisher.place | United Kingdom | - |
| dc.identifier.partofdoi | 10.1177/1744806920907173 | - |