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Article: GRP per capita and Hospital Characteristics Associated with Intravenous Tissue Plasminogen Activator Adherence Rate: Evidence from the Chinese Stroke Center Alliance
Title | GRP per capita and Hospital Characteristics Associated with Intravenous Tissue Plasminogen Activator Adherence Rate: Evidence from the Chinese Stroke Center Alliance |
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Authors | |
Keywords | statistics stroke thrombolysis |
Issue Date | 2021 |
Publisher | BMJ Publishing Group: Open Access Journals. The Journal's web site is located at https://svn.bmj.com/ |
Citation | Stroke and Vascular Neurology, 2021, Epub 2021-01-11 How to Cite? |
Abstract | Background: Timely delivery of intravenous tissue plasminogen activator (IV-rt PA) is pivotal to eligible patients who had a stroke while achieving higher rates of IV-rt PA has been problematic. This paper focuses on investigating influential factors associated with the administration of IV-rt PA, primarily per capita gross regional product (GRP) and healthcare system factors. Methods: The study included 980 hospitals in the Chinese Stroke Center Alliance where 158 003 patients who had an acute ischaemic stroke received IV-rt PA between August 2015 and August 2019. The adherence rate to IV-rt PA within 4.5 hours time window in each hospital was the primary outcome. Influential factors were grouped into two categories: macroeconomic status and hospital characteristics. The outcome was analysed using multivariable linear regression. Results: GRP per capita (β=2.37, p<0.001), hospital stroke centre certification (β=3.77, p<0.001), number of neurologists (β=0.12, p<0.001), existence of emergency services for neurological treatment (β=7.43, p=0.014), presence of emergency department (β=10.03, p=0.019) and cooperating with emergency centre (β=4.65, p=0.029) were significantly positively associated with the adherence rate to IV-rt PA. Conclusions: Higher GRP per capita, affluent neurological personnel, well-equipped emergency services for neurological treatment and routine cooperation with the emergency centre were important for enhancing the adherence rate to IV-rt PA among patients who had an acute ischaemic stroke in China. |
Persistent Identifier | http://hdl.handle.net/10722/295755 |
ISSN | 2023 Impact Factor: 4.4 2023 SCImago Journal Rankings: 1.857 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | ZHENG, S | - |
dc.contributor.author | Lyu, TJ | - |
dc.contributor.author | Li, Z | - |
dc.contributor.author | Gu, H | - |
dc.contributor.author | Yang, X | - |
dc.contributor.author | Wang, C | - |
dc.contributor.author | Li, H | - |
dc.contributor.author | Jiang, Y | - |
dc.contributor.author | Shen, H | - |
dc.contributor.author | Wang, Y | - |
dc.date.accessioned | 2021-02-08T08:13:33Z | - |
dc.date.available | 2021-02-08T08:13:33Z | - |
dc.date.issued | 2021 | - |
dc.identifier.citation | Stroke and Vascular Neurology, 2021, Epub 2021-01-11 | - |
dc.identifier.issn | 2059-8688 | - |
dc.identifier.uri | http://hdl.handle.net/10722/295755 | - |
dc.description.abstract | Background: Timely delivery of intravenous tissue plasminogen activator (IV-rt PA) is pivotal to eligible patients who had a stroke while achieving higher rates of IV-rt PA has been problematic. This paper focuses on investigating influential factors associated with the administration of IV-rt PA, primarily per capita gross regional product (GRP) and healthcare system factors. Methods: The study included 980 hospitals in the Chinese Stroke Center Alliance where 158 003 patients who had an acute ischaemic stroke received IV-rt PA between August 2015 and August 2019. The adherence rate to IV-rt PA within 4.5 hours time window in each hospital was the primary outcome. Influential factors were grouped into two categories: macroeconomic status and hospital characteristics. The outcome was analysed using multivariable linear regression. Results: GRP per capita (β=2.37, p<0.001), hospital stroke centre certification (β=3.77, p<0.001), number of neurologists (β=0.12, p<0.001), existence of emergency services for neurological treatment (β=7.43, p=0.014), presence of emergency department (β=10.03, p=0.019) and cooperating with emergency centre (β=4.65, p=0.029) were significantly positively associated with the adherence rate to IV-rt PA. Conclusions: Higher GRP per capita, affluent neurological personnel, well-equipped emergency services for neurological treatment and routine cooperation with the emergency centre were important for enhancing the adherence rate to IV-rt PA among patients who had an acute ischaemic stroke in China. | - |
dc.language | eng | - |
dc.publisher | BMJ Publishing Group: Open Access Journals. The Journal's web site is located at https://svn.bmj.com/ | - |
dc.relation.ispartof | Stroke and Vascular Neurology | - |
dc.rights | This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. | - |
dc.subject | statistics | - |
dc.subject | stroke | - |
dc.subject | thrombolysis | - |
dc.title | GRP per capita and Hospital Characteristics Associated with Intravenous Tissue Plasminogen Activator Adherence Rate: Evidence from the Chinese Stroke Center Alliance | - |
dc.type | Article | - |
dc.identifier.email | Shen, H: haipeng@hku.hk | - |
dc.identifier.authority | Shen, H=rp02082 | - |
dc.description.nature | published_or_final_version | - |
dc.identifier.doi | 10.1136/svn-2020-000633 | - |
dc.identifier.scopus | eid_2-s2.0-85099391339 | - |
dc.identifier.hkuros | 321104 | - |
dc.identifier.volume | Epub 2021-01-11 | - |
dc.identifier.isi | WOS:000702449600004 | - |
dc.publisher.place | United Kingdom | - |