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- Publisher Website: 10.1155/2020/8840082
- Scopus: eid_2-s2.0-85096742461
- PMID: 33224538
- WOS: WOS:000593505400001
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Article: Headache in a Child with Pseudohypoparathyroidism: An Alarming Symptom Not to Miss
Title | Headache in a Child with Pseudohypoparathyroidism: An Alarming Symptom Not to Miss |
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Authors | |
Keywords | Pseudohypoparathyroidism Albright Syndrome Brachydactyly |
Issue Date | 2020 |
Publisher | Hindawi Publishing Corporation. The Journal's web site is located at https://www.hindawi.com/journals/crie/ |
Citation | Case Reports in Endocrinology, 2020, v. 2020, p. article no. 8840082 How to Cite? |
Abstract | Background. While the endocrine manifestations of pseudohypoparathyroidism are well known, less is known about the associated brain and spine abnormalities. These abnormalities may present with nonspecific symptoms in the paediatric population, and lack of awareness to these uncommon manifestations of the disease may result in a delay in necessary intervention. Case Presentation. We herein present a case of known pseudohypoparathyroidism type 1a who presented initially with minor head injury. She later developed progressive worsening headache, increased irritability, and vomiting. Repeated imaging showed hydrocephalus and Chiari malformation type 1 necessitating emergency craniectomy. Conclusion. Growth hormone deficiency, a common manifestation of pseudohypoparathyroidism type 1a, results in underdevelopment of the posterior cranial fossa and may account for the higher incidence of Chiari malformation in this group of patients. Other associated neurological features reported in pseudohypoparathyroidism type 1a include spinal stenosis, syringomyelia, and craniosynostosis. While less commonly seen, awareness to these associations is important in order to optimize the multidisciplinary care to this group of patients. |
Persistent Identifier | http://hdl.handle.net/10722/293407 |
ISSN | 2023 Impact Factor: 0.9 2023 SCImago Journal Rankings: 0.237 |
PubMed Central ID | |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Poon, SWY | - |
dc.contributor.author | Chung, BHY | - |
dc.contributor.author | Tsang, AMC | - |
dc.contributor.author | Poon, WK | - |
dc.contributor.author | Kita, T | - |
dc.date.accessioned | 2020-11-23T08:16:18Z | - |
dc.date.available | 2020-11-23T08:16:18Z | - |
dc.date.issued | 2020 | - |
dc.identifier.citation | Case Reports in Endocrinology, 2020, v. 2020, p. article no. 8840082 | - |
dc.identifier.issn | 2090-6501 | - |
dc.identifier.uri | http://hdl.handle.net/10722/293407 | - |
dc.description.abstract | Background. While the endocrine manifestations of pseudohypoparathyroidism are well known, less is known about the associated brain and spine abnormalities. These abnormalities may present with nonspecific symptoms in the paediatric population, and lack of awareness to these uncommon manifestations of the disease may result in a delay in necessary intervention. Case Presentation. We herein present a case of known pseudohypoparathyroidism type 1a who presented initially with minor head injury. She later developed progressive worsening headache, increased irritability, and vomiting. Repeated imaging showed hydrocephalus and Chiari malformation type 1 necessitating emergency craniectomy. Conclusion. Growth hormone deficiency, a common manifestation of pseudohypoparathyroidism type 1a, results in underdevelopment of the posterior cranial fossa and may account for the higher incidence of Chiari malformation in this group of patients. Other associated neurological features reported in pseudohypoparathyroidism type 1a include spinal stenosis, syringomyelia, and craniosynostosis. While less commonly seen, awareness to these associations is important in order to optimize the multidisciplinary care to this group of patients. | - |
dc.language | eng | - |
dc.publisher | Hindawi Publishing Corporation. The Journal's web site is located at https://www.hindawi.com/journals/crie/ | - |
dc.relation.ispartof | Case Reports in Endocrinology | - |
dc.rights | This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. | - |
dc.subject | Pseudohypoparathyroidism | - |
dc.subject | Albright Syndrome | - |
dc.subject | Brachydactyly | - |
dc.title | Headache in a Child with Pseudohypoparathyroidism: An Alarming Symptom Not to Miss | - |
dc.type | Article | - |
dc.identifier.email | Poon, SWY: pwy994@hku.hk | - |
dc.identifier.email | Chung, BHY: bhychung@hku.hk | - |
dc.identifier.email | Tsang, AMC: amctsang@hkucc.hku.hk | - |
dc.identifier.email | Poon, WK: pwkg@hkucc.hku.hk | - |
dc.identifier.authority | Chung, BHY=rp00473 | - |
dc.description.nature | published_or_final_version | - |
dc.identifier.doi | 10.1155/2020/8840082 | - |
dc.identifier.pmid | 33224538 | - |
dc.identifier.pmcid | PMC7673925 | - |
dc.identifier.scopus | eid_2-s2.0-85096742461 | - |
dc.identifier.hkuros | 319220 | - |
dc.identifier.volume | 2020 | - |
dc.identifier.spage | article no. 8840082 | - |
dc.identifier.epage | article no. 8840082 | - |
dc.identifier.isi | WOS:000593505400001 | - |
dc.publisher.place | United States | - |
dc.identifier.issnl | 2090-651X | - |