File Download
There are no files associated with this item.
Links for fulltext
(May Require Subscription)
- Publisher Website: 10.1039/C9BM01417A
- Scopus: eid_2-s2.0-85075282021
- PMID: 31626246
- WOS: WOS:000504250100039
- Find via
Supplementary
- Citations:
- Appears in Collections:
Article: “Imitative” click chemistry to form a sticking xerogel for the portable therapy of bacteria-infected wounds
Title | “Imitative” click chemistry to form a sticking xerogel for the portable therapy of bacteria-infected wounds |
---|---|
Authors | |
Keywords | After-treatment Click chemistry Cross-linking structures Infected wounds Staphylococcus aureus |
Issue Date | 2019 |
Publisher | Royal Society of Chemistry. The Journal's web site is located at http://pubs.rsc.org/en/Journals/JournalIssues/bm#!recentarticles&all |
Citation | Biomaterials Science, 2019, v. 7 n. 12, p. 5383-5387 How to Cite? |
Abstract | Xerogels usually possess a stable structure and have a low swelling rate due to their inferior dynamics. Herein, a xerogel was synthesized by “imitative” click chemistry based on lipoic acid for picking up bacteria from wound sites, and thus accelerating tissue repair. The cross-linking structure of disulfide and thioether inside the xerogel not only exhibited good ductility and intrinsic self-healing performance, but also showed superior biocompatibility. The xerogel captured more than 60% of the bacteria Staphylococcus aureus via strong electrostatic adsorption in the colonies with a bacteria count of 106. In addition, this xerogel can stick to the skin in the form of patches in the wounds during therapy for wound healing and can be easily stripped from the skin after treatment, which makes it appropriate for the portable therapy of bacteria-infected wounds in emergency circumstances. |
Persistent Identifier | http://hdl.handle.net/10722/289809 |
ISSN | 2023 Impact Factor: 5.8 2023 SCImago Journal Rankings: 1.206 |
ISI Accession Number ID |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | HUANG, B | - |
dc.contributor.author | LIU, X | - |
dc.contributor.author | TAN, L | - |
dc.contributor.author | CUI, Z | - |
dc.contributor.author | YANG, X | - |
dc.contributor.author | JING, D | - |
dc.contributor.author | ZHENG, D | - |
dc.contributor.author | LI, Z | - |
dc.contributor.author | LIANG, Y | - |
dc.contributor.author | ZHU, S | - |
dc.contributor.author | Yeung, KWK | - |
dc.contributor.author | WANG, X | - |
dc.contributor.author | ZHENG, Y | - |
dc.contributor.author | WU, S | - |
dc.date.accessioned | 2020-10-22T08:17:47Z | - |
dc.date.available | 2020-10-22T08:17:47Z | - |
dc.date.issued | 2019 | - |
dc.identifier.citation | Biomaterials Science, 2019, v. 7 n. 12, p. 5383-5387 | - |
dc.identifier.issn | 2047-4830 | - |
dc.identifier.uri | http://hdl.handle.net/10722/289809 | - |
dc.description.abstract | Xerogels usually possess a stable structure and have a low swelling rate due to their inferior dynamics. Herein, a xerogel was synthesized by “imitative” click chemistry based on lipoic acid for picking up bacteria from wound sites, and thus accelerating tissue repair. The cross-linking structure of disulfide and thioether inside the xerogel not only exhibited good ductility and intrinsic self-healing performance, but also showed superior biocompatibility. The xerogel captured more than 60% of the bacteria Staphylococcus aureus via strong electrostatic adsorption in the colonies with a bacteria count of 106. In addition, this xerogel can stick to the skin in the form of patches in the wounds during therapy for wound healing and can be easily stripped from the skin after treatment, which makes it appropriate for the portable therapy of bacteria-infected wounds in emergency circumstances. | - |
dc.language | eng | - |
dc.publisher | Royal Society of Chemistry. The Journal's web site is located at http://pubs.rsc.org/en/Journals/JournalIssues/bm#!recentarticles&all | - |
dc.relation.ispartof | Biomaterials Science | - |
dc.subject | After-treatment | - |
dc.subject | Click chemistry | - |
dc.subject | Cross-linking structures | - |
dc.subject | Infected wounds | - |
dc.subject | Staphylococcus aureus | - |
dc.title | “Imitative” click chemistry to form a sticking xerogel for the portable therapy of bacteria-infected wounds | - |
dc.type | Article | - |
dc.identifier.email | Yeung, KWK: wkkyeung@hku.hk | - |
dc.identifier.authority | Yeung, KWK=rp00309 | - |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.1039/C9BM01417A | - |
dc.identifier.pmid | 31626246 | - |
dc.identifier.scopus | eid_2-s2.0-85075282021 | - |
dc.identifier.hkuros | 317564 | - |
dc.identifier.volume | 7 | - |
dc.identifier.issue | 12 | - |
dc.identifier.spage | 5383 | - |
dc.identifier.epage | 5387 | - |
dc.identifier.isi | WOS:000504250100039 | - |
dc.publisher.place | United Kingdom | - |
dc.identifier.issnl | 2047-4830 | - |